GR3016981T3 - Signal peptide and DNA sequences coding thereof. - Google Patents
Signal peptide and DNA sequences coding thereof.Info
- Publication number
- GR3016981T3 GR3016981T3 GR950402097T GR950402097T GR3016981T3 GR 3016981 T3 GR3016981 T3 GR 3016981T3 GR 950402097 T GR950402097 T GR 950402097T GR 950402097 T GR950402097 T GR 950402097T GR 3016981 T3 GR3016981 T3 GR 3016981T3
- Authority
- GR
- Greece
- Prior art keywords
- amino acids
- signal peptide
- dna sequences
- sequences coding
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8811188A FR2636643B1 (fr) | 1988-08-24 | 1988-08-24 | Peptide-signal, sequences d'adn codant pour celui-ci, vecteurs d'expression portant l'une de ces sequences et procede de production periplasmique d'un polypeptide |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3016981T3 true GR3016981T3 (en) | 1995-11-30 |
Family
ID=9369498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR950402097T GR3016981T3 (en) | 1988-08-24 | 1995-08-02 | Signal peptide and DNA sequences coding thereof. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0356335B1 (el) |
JP (1) | JP2535076B2 (el) |
AT (1) | ATE122398T1 (el) |
CA (1) | CA1334944C (el) |
DE (1) | DE68922549T2 (el) |
ES (1) | ES2074087T3 (el) |
FR (1) | FR2636643B1 (el) |
GR (1) | GR3016981T3 (el) |
PT (1) | PT91511B (el) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4009268A1 (de) * | 1990-03-22 | 1991-09-26 | Consortium Elektrochem Ind | Sekretion von hirudinderivaten |
US6514730B1 (en) | 1991-03-21 | 2003-02-04 | Consortium für elektrochemische Industrie GmbH | Secretion of hirudin derivatives |
ES2263626T3 (es) * | 2000-06-05 | 2006-12-16 | Corixa Corporation | Peptidos lider para potenciar la secrecion de proteina recombinante a partir de una celula hospedante. |
FR2957598B1 (fr) | 2010-03-17 | 2015-12-04 | Lfb Biotechnologies | Nouveau peptide signal, et son utilisation pour la production de proteines recombinantes |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3587205T2 (de) * | 1984-07-30 | 1993-08-26 | Wakunaga Seiyaku Kk | Verfahren zur herstellung eines proteins und dafuer zu verwendender vektor, rekombinante dns und transformierte zelle. |
DE3586386T2 (de) * | 1984-10-05 | 1993-01-14 | Genentech Inc | Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung. |
-
1988
- 1988-08-24 FR FR8811188A patent/FR2636643B1/fr not_active Expired - Lifetime
-
1989
- 1989-08-22 PT PT91511A patent/PT91511B/pt not_active IP Right Cessation
- 1989-08-23 AT AT89402328T patent/ATE122398T1/de not_active IP Right Cessation
- 1989-08-23 ES ES89402328T patent/ES2074087T3/es not_active Expired - Lifetime
- 1989-08-23 DE DE68922549T patent/DE68922549T2/de not_active Expired - Lifetime
- 1989-08-23 EP EP89402328A patent/EP0356335B1/fr not_active Expired - Lifetime
- 1989-08-23 CA CA000609139A patent/CA1334944C/en not_active Expired - Lifetime
- 1989-08-24 JP JP1220106A patent/JP2535076B2/ja not_active Expired - Lifetime
-
1995
- 1995-08-02 GR GR950402097T patent/GR3016981T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2074087T3 (es) | 1995-09-01 |
ATE122398T1 (de) | 1995-05-15 |
PT91511B (pt) | 1995-07-18 |
FR2636643B1 (fr) | 1990-12-28 |
EP0356335A1 (fr) | 1990-02-28 |
DE68922549D1 (de) | 1995-06-14 |
EP0356335B1 (fr) | 1995-05-10 |
DE68922549T2 (de) | 1996-01-18 |
CA1334944C (en) | 1995-03-28 |
PT91511A (pt) | 1990-03-08 |
JP2535076B2 (ja) | 1996-09-18 |
JPH02257883A (ja) | 1990-10-18 |
FR2636643A1 (fr) | 1990-03-23 |
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