GR1001172B - Μικροσωματιδια της μεμβρανης αιμοπεταλιων. - Google Patents

Μικροσωματιδια της μεμβρανης αιμοπεταλιων.

Info

Publication number
GR1001172B
GR1001172B GR900100286A GR900100286A GR1001172B GR 1001172 B GR1001172 B GR 1001172B GR 900100286 A GR900100286 A GR 900100286A GR 900100286 A GR900100286 A GR 900100286A GR 1001172 B GR1001172 B GR 1001172B
Authority
GR
Greece
Prior art keywords
platelet membrane
microparticles
membrane microparticles
fraction
gpiib
Prior art date
Application number
GR900100286A
Other languages
English (en)
Other versions
GR900100286A (en
Inventor
C Francis Dr Chao
Original Assignee
Prp Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prp Inc filed Critical Prp Inc
Publication of GR900100286A publication Critical patent/GR900100286A/el
Publication of GR1001172B publication Critical patent/GR1001172B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Παρέχεται θερμικώς κατεργασθέν, ιϊκώς αδρανοποιηθέν κλάσμα μικροσωματιδίων μεμβράνης αιμοπεταλίων. Τα μικροσωματίδια δύνανται να παρασκευασθούν εξ αιμοπεταλίων ληξάσης ημερομηνίας. Το κλάσμα μικροσωματιδίων είναι ουσιαστικώς ελεύθερον αλλο-αντιγόνων και συμπλόκων GPIIb/IIIa και δύναται να χρησιμοποιηθεί ως φαρμακευτικόν παρασκεύασμα εις μεταγγίσεις. ω
GR900100286A 1989-04-14 1990-04-17 Μικροσωματιδια της μεμβρανης αιμοπεταλιων. GR1001172B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/337,916 US5185160A (en) 1984-06-21 1989-04-14 Platelet membrane microvesicles

Publications (2)

Publication Number Publication Date
GR900100286A GR900100286A (en) 1991-09-27
GR1001172B true GR1001172B (el) 1993-06-07

Family

ID=23322568

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100286A GR1001172B (el) 1989-04-14 1990-04-17 Μικροσωματιδια της μεμβρανης αιμοπεταλιων.

Country Status (16)

Country Link
US (1) US5185160A (el)
EP (2) EP0467991B1 (el)
JP (1) JP2972329B2 (el)
KR (1) KR0162094B1 (el)
AT (1) ATE169501T1 (el)
AU (2) AU649398B2 (el)
CA (1) CA2051659C (el)
DE (1) DE69032559T2 (el)
DK (1) DK0467991T3 (el)
ES (1) ES2118721T3 (el)
FI (1) FI107702B (el)
GR (1) GR1001172B (el)
HU (1) HU214884B (el)
IE (1) IE990035A1 (el)
NO (1) NO306761B1 (el)
WO (1) WO1990012581A1 (el)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332578A (en) * 1989-04-14 1994-07-26 Prp, Inc. Platelet membrane microparticles
US5428008A (en) * 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
US5358844A (en) * 1993-02-18 1994-10-25 Brigham And Women's Hospital, Inc. Preservation of blood platelets
US5462752A (en) * 1994-07-28 1995-10-31 Prp, Inc. Inhibition of platelet binding
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
DK1351697T3 (da) * 2001-01-18 2014-01-20 Georg Watzek Lægemiddel til fremme af regenerationen af væv
US20050191286A1 (en) * 2004-02-09 2005-09-01 Gandy James B. Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair
US20060004189A1 (en) * 2004-07-02 2006-01-05 James Gandy Compositions for treating wounds and processes for their preparation
US20060142198A1 (en) * 2004-07-02 2006-06-29 Wound Care Partners Llc Compositions for treating wounds and processes for their preparation
US20060165667A1 (en) * 2004-12-03 2006-07-27 Case Western Reserve University Novel methods, compositions and devices for inducing neovascularization
DE102006045550A1 (de) * 2006-09-25 2008-04-03 Dade Behring Marburg Gmbh Verfahren zur Herstellung von agglutionationsfähigen Thrombozytenfragmenten und deren Verwendung
EP3584310B1 (en) 2008-09-16 2024-04-17 Mayo Foundation for Medical Education and Research Compositions containing platelet contents
CA2949225A1 (en) 2014-05-16 2015-11-19 Mayo Foundation For Medical Education And Research Cell culture media compositions for primary cells
EP3265116B1 (en) * 2015-03-04 2021-06-02 University of Rochester Systemic and topical application of platelet microparticles to treat bleeding in trauma patients
US10596123B2 (en) * 2015-03-11 2020-03-24 Mayo Foundation For Medical Education And Research Exosome delivery technology
WO2016205144A1 (en) * 2015-06-14 2016-12-22 Bluecircle Therapeutics, Inc. Compositions of platelet-derived theranostics and uses thereof
CA3121200A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
US11767511B2 (en) 2018-11-30 2023-09-26 Cellphire, Inc. Platelets as delivery agents
SG11202112054WA (en) 2019-05-03 2021-11-29 Cellphire Inc Materials and methods for producing blood products
CA3150936A1 (en) 2019-08-16 2021-02-25 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
CA3170198A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets
WO2021232015A1 (en) * 2020-05-15 2021-11-18 Cellphire, Inc. Platelet derived extracellular vesicles
WO2024192173A1 (en) * 2023-03-14 2024-09-19 Cellphire, Inc. Hla-characterized platelet derivative compositions, and methods of making, selecting and using such compositions
CN117643621B (zh) * 2023-10-27 2024-07-02 江苏省人民医院（南京医科大学第一附属医院） 一种溶栓药PLT-r-SAK及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994438A (en) * 1981-11-02 1991-02-19 Cedars Sinai Medical Center Heat treatment of lyophilized plasma fractions
US4456590B2 (en) * 1981-11-02 1989-05-30 Heat treatment of lyphilized blood clotting factor viii concentrate
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4760131A (en) * 1986-04-23 1988-07-26 Collagen Corporation Wound-healing composition
US4764463A (en) * 1986-10-30 1988-08-16 The University Of Tennessee Research Corporation Platelet cyropreservation
US4753797A (en) * 1987-06-24 1988-06-28 Miles Laboratories, Inc. Enhancing platelet morphology prior to patient use

Also Published As

Publication number Publication date
EP0467991B1 (en) 1998-08-12
CA2051659C (en) 2001-08-07
AU652317B2 (en) 1994-08-18
ATE169501T1 (de) 1998-08-15
WO1990012581A1 (en) 1990-11-01
GR900100286A (en) 1991-09-27
FI914819A0 (fi) 1991-10-11
FI107702B (fi) 2001-09-28
JPH04506451A (ja) 1992-11-12
HU214884B (hu) 2000-03-28
NO914024D0 (no) 1991-10-14
EP0815866A3 (en) 1998-08-12
EP0815866A2 (en) 1998-01-07
HU903374D0 (en) 1991-12-30
EP0467991A1 (en) 1992-01-29
DE69032559D1 (de) 1998-09-17
US5185160A (en) 1993-02-09
DE69032559T2 (de) 1999-01-07
NO306761B1 (no) 1999-12-20
EP0467991A4 (en) 1993-01-07
NO914024L (no) 1991-10-14
AU4195093A (en) 1993-10-07
KR920700661A (ko) 1992-08-10
AU649398B2 (en) 1994-05-26
IE990035A1 (en) 2000-11-01
ES2118721T3 (es) 1998-10-01
HUT61200A (en) 1992-12-28
AU5538890A (en) 1990-11-16
JP2972329B2 (ja) 1999-11-08
DK0467991T3 (da) 1999-02-01
KR0162094B1 (ko) 1998-12-01
CA2051659A1 (en) 1990-10-15

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