GR1000251B - Πολυπεπτιδικες σειρες προικισμενες με ανοσολογικη δραση. - Google Patents

Πολυπεπτιδικες σειρες προικισμενες με ανοσολογικη δραση.

Info

Publication number
GR1000251B
GR1000251B GR880100576A GR880100576A GR1000251B GR 1000251 B GR1000251 B GR 1000251B GR 880100576 A GR880100576 A GR 880100576A GR 880100576 A GR880100576 A GR 880100576A GR 1000251 B GR1000251 B GR 1000251B
Authority
GR
Greece
Prior art keywords
polypeptidic
series
asn
immunologically active
polypeptides
Prior art date
Application number
GR880100576A
Other languages
English (en)
Other versions
GR880100576A (en
Inventor
Fabio Bonelli
Antonello Pessi
Silvio Antonio Verdini
Original Assignee
Eniricerche Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa filed Critical Eniricerche Spa
Publication of GR880100576A publication Critical patent/GR880100576A/el
Publication of GR1000251B publication Critical patent/GR1000251B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Συνθετικά πολυπεπτίδια αποτελούμενα εκ δύο τουλάχιστον διαδοχικών επαναληπτικών μονάδων (Asn-Asn-Pro) αποτελούν ισχυρά μέσα ανοσοποιήσεως επί ζώων δοκιμασίας. Τα σχηματιζόμενα αντισώματα αναγνωρίζουν τόσον τα συνθετικά πολυπεπτίδια όσον και τον κύριον ανοσολογικόν παράγοντα της περιφερειακής πρωτείνηςτων σποροζωιδίων του PLASMODIUM FALCIPARUM. Τα εν λόγω πολυπεπτίδια τα οποία δύνανται να ληφθούν υπό καθαράν μορφήν, είναι ιδιαιτέρως χρήσιμα προς παρασκευήν ανθελονοσιακών εμβολίων και διαγνωστικών ΚΙΤ προς προσδιορισμόν μολύνσεων εξ ελονοσίας. ω
GR880100576A 1987-09-11 1988-09-02 Πολυπεπτιδικες σειρες προικισμενες με ανοσολογικη δραση. GR1000251B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21892/87A IT1223301B (it) 1987-09-11 1987-09-11 Polipeptidi sequenziali immunologicamente attivi

Publications (2)

Publication Number Publication Date
GR880100576A GR880100576A (en) 1989-06-22
GR1000251B true GR1000251B (el) 1992-05-12

Family

ID=11188316

Family Applications (1)

Application Number Title Priority Date Filing Date
GR880100576A GR1000251B (el) 1987-09-11 1988-09-02 Πολυπεπτιδικες σειρες προικισμενες με ανοσολογικη δραση.

Country Status (15)

Country Link
US (1) US5219987A (el)
AT (1) AT398427B (el)
BE (1) BE1003232A3 (el)
CA (1) CA1335320C (el)
CH (1) CH676989A5 (el)
DE (1) DE3830565A1 (el)
ES (1) ES2011679A6 (el)
FR (1) FR2621919B1 (el)
GB (1) GB2209755B (el)
GR (1) GR1000251B (el)
IT (1) IT1223301B (el)
NL (1) NL8802201A (el)
OA (1) OA08951A (el)
SE (1) SE8803062L (el)
ZA (1) ZA885744B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ233255A (en) * 1989-04-11 1993-02-25 Chiron Corp Plasmodium cs protein analogues lacking one or more of the repeat epitopes, and containing at least one nonrepeat flanking epitope
AU2003263212A1 (en) * 2002-08-14 2004-03-03 Avidis Sa Heteropolymeric compound comprising a scaffold, an adjuvant and an antigen, and its use
JP2007528210A (ja) * 2003-08-12 2007-10-11 アヴィディス エスアー Ｃ４ｂｐコアタンパク質及び単量体抗原を含む生成物及びその使用
WO2005034350A1 (ja) * 2003-09-30 2005-04-14 Mitsubishi Denki Kabushiki Kaisha 可変電力分配器並びにその誤差検出方法及び設定値補正方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929756A (en) * 1973-11-21 1975-12-30 Univ Brandeis Synthetically produced tridecapeptide having the same activity as the hypothalamic substance, neurotensin
US4132746A (en) * 1976-07-09 1979-01-02 University Of Alabama, Birmingham Medical & Education Foundation Synthetic elastomeric insoluble cross-linked polypentapeptide
SE453510B (sv) * 1980-12-29 1988-02-08 Toyo Jozo Kk Peptid for analys av humant paratyroidhormon
US4707357A (en) * 1984-06-26 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor
NZ213303A (en) * 1984-09-12 1988-09-29 Univ New York Plasmodium protein, dna sequence and vaccine
ES8800273A1 (es) * 1985-03-28 1987-11-01 Univ New York Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
IT1187710B (it) * 1985-07-25 1987-12-23 Eniricerche Spa Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche
IT1198225B (it) * 1986-12-04 1988-12-21 Eniricerche Spa Polipeptidi immunologicamente attivi utili per la preparazione di vaccini antimalaria e di kits diagnostici per la determinazione di anticorpi antisporozoita

Also Published As

Publication number Publication date
GB2209755B (en) 1991-06-05
DE3830565C2 (el) 1991-08-14
US5219987A (en) 1993-06-15
BE1003232A3 (fr) 1992-02-04
OA08951A (en) 1990-11-30
CA1335320C (en) 1995-04-18
NL8802201A (nl) 1989-04-03
ES2011679A6 (es) 1990-02-01
FR2621919B1 (fr) 1991-12-06
GB8819030D0 (en) 1988-09-14
DE3830565A1 (de) 1989-03-23
GB2209755A (en) 1989-05-24
FR2621919A1 (fr) 1989-04-21
IT1223301B (it) 1990-09-19
IT8721892A0 (it) 1987-09-11
GR880100576A (en) 1989-06-22
ZA885744B (en) 1989-04-26
AT398427B (de) 1994-12-27
ATA221488A (de) 1994-04-15
SE8803062D0 (sv) 1988-09-01
SE8803062L (sv) 1989-03-12
CH676989A5 (el) 1991-03-28

Similar Documents

Publication Publication Date Title
IT1164858B (it) Procedimento per la preparazione di vaccini a base di virus con proteine superficiali ricombinanti e prodotto ottenuto
IT8967503A0 (it) Procedimento e dispositivo di rico noscimento del contorno di immaginiin movimento
IT1226861B (it) Vaccini contenenti antigeni tumorali e coadiuvanti e relativo procedimento di preparazione
FI903292A0 (fi) T-cellepitop som baerarmolekyler foer konjugerade vacciner.
NO912825D0 (no) Fremgangsmaate for fremstilling av cokonjugate vaksiner omfattende immunogenisk protein, hiv-beslektede peptider og anioniske grupper.
DK646688A (da) Farmaceutiske praeparater
BR9610679A (pt) Antígenos de leishmania para uso na terapia e disgnose da leishmaniose
NZ233085A (en) Eimeria tenella 100kd immunogenic peptide, vectors, antibodies and vaccines
GR1000251B (el) Πολυπεπτιδικες σειρες προικισμενες με ανοσολογικη δραση.
ES553425A0 (es) Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
IL83324A0 (en) Polypeptides useful in diagnosis of mycoplasma infections in swine and recombinant-dna methods for manufacturing same
DE3879968D1 (de) Malaria-impfstoff aus copolymerem protein.
ATE132754T1 (de) Coccidiosis-impfstoff
ES2005753A6 (es) Procedimiento para la preparacion de polipeptidos inmunologicamente activos utiles para la obtencion de vacunas antimalaria y para la deteccion de enfermedades paludicas.
DE69230106T2 (de) Peptid-antigene bestehend aus multi-determinanten, die die t-helfer lymphozyten-antwort gegen hiv in einem weiten bereich von betroffenen menschen stimulieren
DE69229899D1 (de) Schützendes malaria sporozoiten-oberflächenprotein immunogen und gen
IT1233419B (it) Peptidi sintetici immunologicamente attivi utili per la preparazione di un vaccino antimalaria
DE68922896D1 (de) RHOPTRY-MEMBRAN-ANTIGEN VON -i(PLASMODIUM FALCIPARUM).
ATE201046T1 (de) Polypeptide und dafür kodierende dns, die mit humanen malariaparasiten assoziiert sind
TH809EX (th) โปรโตโซลแอนติเจล (กรรมวิธี)
IT8919110A0 (it) Peptidi sintetici e loro uso come carriers universali per la preparazione di coniugati immunogenici adatti per lo sviluppo di vaccini sintetici.
GR900100595A (en) Cytokine and hormone carriers for conjugate vaccines
IT8922409A0 (it) Peptidi sintetici e loro uso come carriers universali per la preparazione di coniugati immunogenici adatti per lo sviluppo di vaccini sintetici
ATE102252T1 (de) Rekombinantes gefluegelpockenvirus, expressionsvektoren fuer heterologische proteine und davon derivierte gefluegelvakzine.
ATE87937T1 (de) Malaria-impfstoff aus copolymerem protein.