GEP20146001B - Cancer prophylactic/therapeutic agent - Google Patents
Cancer prophylactic/therapeutic agentInfo
- Publication number
- GEP20146001B GEP20146001B GEAP200912275A GEAP2009012275A GEP20146001B GE P20146001 B GEP20146001 B GE P20146001B GE AP200912275 A GEAP200912275 A GE AP200912275A GE AP2009012275 A GEAP2009012275 A GE AP2009012275A GE P20146001 B GEP20146001 B GE P20146001B
- Authority
- GE
- Georgia
- Prior art keywords
- therapeutic agent
- cancer prophylactic
- prophylactic
- cancer
- cer
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000003098 androgen Substances 0.000 abstract 1
- KAHDONZOCXSKII-NJVVDGNHSA-N kisspeptin Chemical class C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H]1N(CCC1)C(=O)[C@H]1N(CCC1)C(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)O)C1=CN=CN1 KAHDONZOCXSKII-NJVVDGNHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20388708P | 2008-12-29 | 2008-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20146001B true GEP20146001B (en) | 2014-01-10 |
Family
ID=42025816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP200912275A GEP20146001B (en) | 2008-12-29 | 2009-12-28 | Cancer prophylactic/therapeutic agent |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US20110312898A1 (enExample) |
| EP (1) | EP2379053A1 (enExample) |
| JP (1) | JP2012513982A (enExample) |
| KR (1) | KR20110111420A (enExample) |
| CN (1) | CN102333520B (enExample) |
| AR (1) | AR074918A1 (enExample) |
| AU (1) | AU2009334235A1 (enExample) |
| BR (1) | BRPI0923663A2 (enExample) |
| CA (1) | CA2748517A1 (enExample) |
| CL (1) | CL2011001519A1 (enExample) |
| CO (1) | CO6382105A2 (enExample) |
| CR (1) | CR20110374A (enExample) |
| DO (1) | DOP2011000163A (enExample) |
| EA (1) | EA019738B1 (enExample) |
| EC (1) | ECSP11011166A (enExample) |
| GE (1) | GEP20146001B (enExample) |
| IL (1) | IL212913A0 (enExample) |
| MA (1) | MA32935B1 (enExample) |
| MX (1) | MX2011006170A (enExample) |
| NZ (1) | NZ593381A (enExample) |
| PE (1) | PE20110939A1 (enExample) |
| TN (1) | TN2011000250A1 (enExample) |
| TW (1) | TW201029660A (enExample) |
| UY (1) | UY32367A (enExample) |
| WO (1) | WO2010076896A1 (enExample) |
| ZA (1) | ZA201103627B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2275433B1 (en) * | 2008-04-30 | 2017-06-07 | Kyoto University | Metastin derivative and use thereof |
| MX2012006441A (es) * | 2009-12-22 | 2012-06-28 | Takeda Pharmaceutical | Formulacion de liberacion sostenida. |
| EP2585091B1 (en) * | 2010-06-25 | 2014-09-10 | Takeda Pharmaceutical Company Limited | Sustained-release formulation comprising a metastin derivative |
| JP6253146B2 (ja) * | 2014-02-04 | 2017-12-27 | 国立大学法人山口大学 | 新規なペプチド誘導体及びこれを含有する医薬 |
| WO2016099232A2 (ru) * | 2014-10-20 | 2016-06-23 | Товарищество С Ограниченной Ответственностью "Фармацевтическая Компания "Ромат" | Фармацевтический состав лечебно-профилактического действия и способ его приготовления |
| CA3038865A1 (en) | 2016-09-30 | 2018-04-05 | Myovant Sciences Gmbh | Methods of treating female infertility |
| WO2024206577A1 (en) * | 2023-03-28 | 2024-10-03 | Radionetics Oncology, Inc. | Kisspeptin receptor (kiss1r) targeted therapeutics and uses thereof |
| WO2025217074A1 (en) | 2024-04-08 | 2025-10-16 | Radionetics Oncology, Inc. | Kisspeptin receptor (kiss1r) targeted therapeutics and uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004063221A1 (ja) * | 2002-12-26 | 2004-07-29 | Takeda Pharmaceutical Company Limited | メタスチン誘導体およびその用途 |
| US6800611B2 (en) * | 2003-01-06 | 2004-10-05 | Takeda Chemical Industries, Ltd. | Metastin derivatives and their use |
| WO2006001499A2 (en) * | 2004-06-25 | 2006-01-05 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| CN1972959A (zh) * | 2004-06-25 | 2007-05-30 | 武田药品工业株式会社 | 转移素衍生物及其用途 |
| AR058584A1 (es) * | 2005-12-22 | 2008-02-13 | Takeda Pharmaceutical | Derivados de metastina y uso de los mismos |
-
2009
- 2009-12-28 GE GEAP200912275A patent/GEP20146001B/en unknown
- 2009-12-28 BR BRPI0923663A patent/BRPI0923663A2/pt not_active IP Right Cessation
- 2009-12-28 AR ARP090105129A patent/AR074918A1/es not_active Application Discontinuation
- 2009-12-28 AU AU2009334235A patent/AU2009334235A1/en not_active Abandoned
- 2009-12-28 PE PE2011001293A patent/PE20110939A1/es not_active Application Discontinuation
- 2009-12-28 NZ NZ593381A patent/NZ593381A/xx not_active IP Right Cessation
- 2009-12-28 EA EA201100882A patent/EA019738B1/ru not_active IP Right Cessation
- 2009-12-28 JP JP2011543072A patent/JP2012513982A/ja active Pending
- 2009-12-28 US US13/142,414 patent/US20110312898A1/en not_active Abandoned
- 2009-12-28 CN CN2009801575361A patent/CN102333520B/zh not_active Expired - Fee Related
- 2009-12-28 KR KR1020117017317A patent/KR20110111420A/ko not_active Withdrawn
- 2009-12-28 CA CA2748517A patent/CA2748517A1/en not_active Abandoned
- 2009-12-28 UY UY0001032367A patent/UY32367A/es not_active Application Discontinuation
- 2009-12-28 WO PCT/JP2009/071919 patent/WO2010076896A1/en not_active Ceased
- 2009-12-28 TW TW098145251A patent/TW201029660A/zh unknown
- 2009-12-28 EP EP09801574A patent/EP2379053A1/en not_active Withdrawn
- 2009-12-28 MA MA33959A patent/MA32935B1/fr unknown
- 2009-12-28 MX MX2011006170A patent/MX2011006170A/es not_active Application Discontinuation
-
2011
- 2011-05-16 IL IL212913A patent/IL212913A0/en unknown
- 2011-05-17 TN TN2011000250A patent/TN2011000250A1/fr unknown
- 2011-05-17 ZA ZA2011/03627A patent/ZA201103627B/en unknown
- 2011-05-31 DO DO2011000163A patent/DOP2011000163A/es unknown
- 2011-06-20 CL CL2011001519A patent/CL2011001519A1/es unknown
- 2011-06-23 CO CO11078830A patent/CO6382105A2/es not_active Application Discontinuation
- 2011-06-29 EC EC2011011166A patent/ECSP11011166A/es unknown
- 2011-06-29 CR CR20110374A patent/CR20110374A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN102333520A (zh) | 2012-01-25 |
| TN2011000250A1 (en) | 2012-12-17 |
| JP2012513982A (ja) | 2012-06-21 |
| AU2009334235A1 (en) | 2010-07-08 |
| UY32367A (es) | 2010-07-30 |
| EP2379053A1 (en) | 2011-10-26 |
| AR074918A1 (es) | 2011-02-23 |
| CO6382105A2 (es) | 2012-02-15 |
| BRPI0923663A2 (pt) | 2016-01-19 |
| NZ593381A (en) | 2013-01-25 |
| IL212913A0 (en) | 2011-07-31 |
| EA201100882A1 (ru) | 2011-12-30 |
| KR20110111420A (ko) | 2011-10-11 |
| CL2011001519A1 (es) | 2012-03-16 |
| ZA201103627B (en) | 2012-09-26 |
| WO2010076896A1 (en) | 2010-07-08 |
| CN102333520B (zh) | 2013-11-06 |
| MA32935B1 (fr) | 2012-01-02 |
| PE20110939A1 (es) | 2012-01-19 |
| CR20110374A (es) | 2011-09-19 |
| MX2011006170A (es) | 2011-06-27 |
| US20110312898A1 (en) | 2011-12-22 |
| DOP2011000163A (es) | 2011-07-31 |
| TW201029660A (en) | 2010-08-16 |
| ECSP11011166A (es) | 2011-07-29 |
| CA2748517A1 (en) | 2010-07-08 |
| EA019738B1 (ru) | 2014-05-30 |
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