GEP19970948B - Method for Production of Imidazolidine - Google Patents

Method for Production of Imidazolidine

Info

Publication number
GEP19970948B
GEP19970948B GEAP19931536A GEAP1993001536A GEP19970948B GE P19970948 B GEP19970948 B GE P19970948B GE AP19931536 A GEAP19931536 A GE AP19931536A GE AP1993001536 A GEAP1993001536 A GE AP1993001536A GE P19970948 B GEP19970948 B GE P19970948B
Authority
GE
Georgia
Prior art keywords
medium
imidazolidine
production
acid
solvent
Prior art date
Application number
GEAP19931536A
Other languages
English (en)
Inventor
Claude Bonne
Pierre Girault
Jacques Perronnet
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of GEP19970948B publication Critical patent/GEP19970948B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electromechanical Clocks (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
GEAP19931536A 1975-10-29 1993-09-09 Method for Production of Imidazolidine GEP19970948B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7533084A FR2329276A1 (fr) 1975-10-29 1975-10-29 Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant

Publications (1)

Publication Number Publication Date
GEP19970948B true GEP19970948B (en) 1997-04-18

Family

ID=9161795

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19931536A GEP19970948B (en) 1975-10-29 1993-09-09 Method for Production of Imidazolidine

Country Status (18)

Country Link
US (1) US4097578A (US07655688-20100202-C00109.png)
JP (1) JPS6011701B2 (US07655688-20100202-C00109.png)
AU (1) AU500542B2 (US07655688-20100202-C00109.png)
BE (1) BE847742A (US07655688-20100202-C00109.png)
BG (1) BG60533B2 (US07655688-20100202-C00109.png)
CA (1) CA1086751A (US07655688-20100202-C00109.png)
CH (1) CH599164A5 (US07655688-20100202-C00109.png)
DE (1) DE2649925C2 (US07655688-20100202-C00109.png)
DK (1) DK152125C (US07655688-20100202-C00109.png)
ES (1) ES452746A1 (US07655688-20100202-C00109.png)
FR (1) FR2329276A1 (US07655688-20100202-C00109.png)
GB (1) GB1518444A (US07655688-20100202-C00109.png)
GE (1) GEP19970948B (US07655688-20100202-C00109.png)
IE (1) IE43875B1 (US07655688-20100202-C00109.png)
LU (2) LU76085A1 (US07655688-20100202-C00109.png)
NL (2) NL187102C (US07655688-20100202-C00109.png)
SE (1) SE430502B (US07655688-20100202-C00109.png)
SU (1) SU596165A3 (US07655688-20100202-C00109.png)

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US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
AU594309B2 (en) * 1984-08-02 1990-03-08 Fernand Labrie Pharmaceutical composition for combination therapy of hormonedependent cancers
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US5084472A (en) * 1986-11-04 1992-01-28 Roussel Application of 1-(3'-trifluoromethyl-4'-nitrophenyl)-4,4'-dimethylimidazoline 2,5-dione in the treatment of hormone-dependent cancers other than that of the prostate
FR2619381B1 (fr) * 1987-08-13 1989-12-08 Roussel Uclaf Nouvelles imidazolidines substituees par un radical hydroxymethyle et un radical phenyl substitue, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant et un intermediaire pour leur preparation
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
FR2656302B1 (fr) * 1989-12-22 1992-05-07 Roussel Uclaf Nouveau procede de preparation de l'anandron et derives de l'anandron.
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR2671348B1 (fr) * 1991-01-09 1993-03-26 Roussel Uclaf Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
USRE35956E (en) * 1991-01-09 1998-11-10 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2685328B1 (fr) * 1991-12-20 1995-12-01 Rhone Poulenc Agrochimie Derives de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides.
US6002016A (en) * 1991-12-20 1999-12-14 Rhone-Poulenc Agrochimie Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones
FR2706456B1 (fr) * 1993-06-18 1996-06-28 Rhone Poulenc Agrochimie Dérivés optiquement actifs de 2-imidazoline-5-ones et 2-imidazoline-5-thiones fongicides.
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US6008370A (en) * 1992-11-25 1999-12-28 Rhone-Poulenc Agrochimie Fungicidal-2-alkoxy/haloalkoxy-1-(mono- or disubstituted)amino-4,4-disubstituted-2-imidazolin-5-ones
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FR2715402B1 (fr) * 1994-01-05 1996-10-04 Roussel Uclaf Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
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FR2725206B1 (fr) * 1994-09-29 1996-12-06 Roussel Uclaf Nouvelles imidazolidines substituees par un heterocycle, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
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IL152719A0 (en) * 2000-06-28 2003-06-24 Bristol Myers Squibb Co Selective androgen receptor modulators and methods for their identification
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EP2656842B1 (en) 2006-03-27 2016-08-10 The Regents of The University of California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
EP3020706A1 (en) 2006-03-29 2016-05-18 The Regents Of The University Of California Diarylthiohydantoin compounds useful for the treatment of a hyperproliferative disorder
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Also Published As

Publication number Publication date
GB1518444A (en) 1978-07-19
JPS6011701B2 (ja) 1985-03-27
DK487476A (da) 1977-04-30
LU88282I2 (fr) 1994-05-04
IE43875B1 (en) 1981-06-17
SU596165A3 (ru) 1978-02-28
LU76085A1 (US07655688-20100202-C00109.png) 1977-05-31
NL187102B (nl) 1991-01-02
FR2329276B1 (US07655688-20100202-C00109.png) 1979-09-14
FR2329276A1 (fr) 1977-05-27
SE7610859L (sv) 1977-04-30
BG60533B2 (bg) 1995-07-28
SE430502B (sv) 1983-11-21
NL187102C (nl) 1991-06-03
AU500542B2 (en) 1979-05-24
NL930079I2 (nl) 1993-10-01
ES452746A1 (es) 1977-10-01
CH599164A5 (US07655688-20100202-C00109.png) 1978-05-12
DE2649925C2 (de) 1986-08-28
BE847742A (fr) 1977-04-28
NL7611576A (nl) 1977-05-03
DE2649925A1 (de) 1977-05-12
US4097578A (en) 1978-06-27
DK152125B (da) 1988-02-01
CA1086751A (fr) 1980-09-30
DK152125C (da) 1988-06-20
AU1909576A (en) 1978-05-04
JPS5257176A (en) 1977-05-11
IE43875L (en) 1977-04-29
NL930079I1 (nl) 1993-09-16

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