GB993458A - Process for the production of 3-oxo-4-hydroxy-4-cyclopenteno-(1,2-16,17)-steroids - Google Patents
Process for the production of 3-oxo-4-hydroxy-4-cyclopenteno-(1,2-16,17)-steroidsInfo
- Publication number
- GB993458A GB993458A GB11084/64A GB1108464A GB993458A GB 993458 A GB993458 A GB 993458A GB 11084/64 A GB11084/64 A GB 11084/64A GB 1108464 A GB1108464 A GB 1108464A GB 993458 A GB993458 A GB 993458A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- keto
- referred
- acid
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 abstract 4
- KZMGYPLQYOPHEL-UHFFFAOYSA-N Boron trifluoride etherate Chemical compound FB(F)F.CCOCC KZMGYPLQYOPHEL-UHFFFAOYSA-N 0.000 abstract 2
- 229930194542 Keto Natural products 0.000 abstract 2
- 239000002841 Lewis acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 125000000468 ketone group Chemical group 0.000 abstract 2
- 150000007517 lewis acids Chemical class 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- 239000002170 aldosterone antagonist Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000003841 chloride salts Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM56328A DE1214225B (de) | 1963-04-01 | 1963-04-01 | Verfahren zur Herstellung neuer Steroide |
| DED0056328 | 1963-04-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB993458A true GB993458A (en) | 1965-05-26 |
Family
ID=25972632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB11084/64A Expired GB993458A (en) | 1963-04-01 | 1964-03-16 | Process for the production of 3-oxo-4-hydroxy-4-cyclopenteno-(1,2-16,17)-steroids |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3290214A (OSRAM) |
| BE (1) | BE645738A (OSRAM) |
| CH (1) | CH444150A (OSRAM) |
| DK (1) | DK112521B (OSRAM) |
| FR (1) | FR3329M (OSRAM) |
| GB (1) | GB993458A (OSRAM) |
| NL (1) | NL6402401A (OSRAM) |
| SE (1) | SE311155B (OSRAM) |
-
1964
- 1964-02-14 CH CH176664A patent/CH444150A/de unknown
- 1964-03-09 NL NL6402401A patent/NL6402401A/xx unknown
- 1964-03-16 GB GB11084/64A patent/GB993458A/en not_active Expired
- 1964-03-19 US US353255A patent/US3290214A/en not_active Expired - Lifetime
- 1964-03-25 DK DK152664AA patent/DK112521B/da unknown
- 1964-03-26 BE BE645738D patent/BE645738A/xx unknown
- 1964-03-26 SE SE3835/64A patent/SE311155B/xx unknown
- 1964-04-01 FR FR969341A patent/FR3329M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BE645738A (OSRAM) | 1964-09-28 |
| CH444150A (de) | 1967-09-30 |
| DK112521B (da) | 1968-12-23 |
| FR3329M (fr) | 1965-05-24 |
| NL6402401A (OSRAM) | 1964-10-02 |
| SE311155B (OSRAM) | 1969-06-02 |
| US3290214A (en) | 1966-12-06 |
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