GB9919957D0 - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
GB9919957D0
GB9919957D0 GBGB9919957.2A GB9919957A GB9919957D0 GB 9919957 D0 GB9919957 D0 GB 9919957D0 GB 9919957 A GB9919957 A GB 9919957A GB 9919957 D0 GB9919957 D0 GB 9919957D0
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
therapeutic agents
substituted
alpha2
convulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9919957.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Priority to GBGB9919957.2A priority Critical patent/GB9919957D0/en
Publication of GB9919957D0 publication Critical patent/GB9919957D0/en
Priority to CA002380452A priority patent/CA2380452C/en
Priority to EP00954717A priority patent/EP1212324B1/en
Priority to DE60006260T priority patent/DE60006260T2/de
Priority to JP2001518708A priority patent/JP2003507479A/ja
Priority to AT00954717T priority patent/ATE253066T1/de
Priority to US10/069,437 priority patent/US6608062B1/en
Priority to ES00954717T priority patent/ES2208404T3/es
Priority to PCT/GB2000/003199 priority patent/WO2001014377A1/en
Priority to AU67077/00A priority patent/AU775008B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
GBGB9919957.2A 1999-08-23 1999-08-23 Therapeutic agents Ceased GB9919957D0 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
GBGB9919957.2A GB9919957D0 (en) 1999-08-23 1999-08-23 Therapeutic agents
AU67077/00A AU775008B2 (en) 1999-08-23 2000-08-17 Imidazo-triazine derivatives as ligands for gaba receptors
JP2001518708A JP2003507479A (ja) 1999-08-23 2000-08-17 Ｇａｂａ受容体リガンドとしてのイミダゾ−トリアジン誘導体
EP00954717A EP1212324B1 (en) 1999-08-23 2000-08-17 Imidazo-triazine derivatives as ligands for gaba receptors
DE60006260T DE60006260T2 (de) 1999-08-23 2000-08-17 Imidazotriazinderivate als gaba rezeptor-liganden
CA002380452A CA2380452C (en) 1999-08-23 2000-08-17 Imidazo-triazine derivatives as ligands for gaba receptors
AT00954717T ATE253066T1 (de) 1999-08-23 2000-08-17 Imidazotriazinderivate als gaba rezeptor-liganden
US10/069,437 US6608062B1 (en) 1999-08-23 2000-08-17 Imidazo-triazine derivatives as ligands for GABA receptors
ES00954717T ES2208404T3 (es) 1999-08-23 2000-08-17 Derivados de imidazo-triazina como ligandos de los receptores de3 gaba.
PCT/GB2000/003199 WO2001014377A1 (en) 1999-08-23 2000-08-17 Imidazo-triazine derivatives as ligands for gaba receptors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9919957.2A GB9919957D0 (en) 1999-08-23 1999-08-23 Therapeutic agents

Publications (1)

Publication Number Publication Date
GB9919957D0 true GB9919957D0 (en) 1999-10-27

Family

ID=10859670

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9919957.2A Ceased GB9919957D0 (en) 1999-08-23 1999-08-23 Therapeutic agents

Country Status (10)

Country Link
US (1) US6608062B1 (https=)
EP (1) EP1212324B1 (https=)
JP (1) JP2003507479A (https=)
AT (1) ATE253066T1 (https=)
AU (1) AU775008B2 (https=)
CA (1) CA2380452C (https=)
DE (1) DE60006260T2 (https=)
ES (1) ES2208404T3 (https=)
GB (1) GB9919957D0 (https=)
WO (1) WO2001014377A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0210127D0 (en) * 2002-05-02 2002-06-12 Merck Sharp & Dohme Therapeutic agents
AU2003252499B2 (en) * 2002-07-12 2007-11-08 Japan Science And Technology Agency Drugs for improving the prognosis of brain injury and a method of screening the same
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
AU2006327300A1 (en) 2005-12-20 2007-06-28 Astrazeneca Ab Substituted Cinnoline derivatives as GABAa-receptor modulators and method for their synthesis
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2068872A1 (en) 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
GB0622472D0 (en) * 2006-11-10 2006-12-20 Addex Pharmaceuticals Sa Novel heterocyclic derivatives
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US20240327413A1 (en) * 2021-06-29 2024-10-03 Zomagen Biosciences Ltd Nlrp3 modulators
IL310992A (en) * 2021-08-25 2024-04-01 Ptc Therapeutics Inc NLRP3 inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422194A (en) * 1967-08-15 1969-01-14 Smithkline Corp The treatment of depression with imidazo(1,2-b)-as-triazines and compositions thereof
ES2194205T3 (es) 1996-07-25 2003-11-16 Merck Sharp & Dohme Derivados de triazolo-piridazina sustituidos como ligandos para los receptores gaba.
CA2346289A1 (en) * 1998-10-16 2000-04-27 Merck Sharp & Dohme Limited Pyrazolo-triazine derivatives as ligands for gaba receptors

Also Published As

Publication number Publication date
EP1212324A1 (en) 2002-06-12
ES2208404T3 (es) 2004-06-16
ATE253066T1 (de) 2003-11-15
US6608062B1 (en) 2003-08-19
WO2001014377A1 (en) 2001-03-01
AU775008B2 (en) 2004-07-15
EP1212324B1 (en) 2003-10-29
CA2380452C (en) 2008-10-28
AU6707700A (en) 2001-03-19
DE60006260T2 (de) 2004-07-29
DE60006260D1 (de) 2003-12-04
JP2003507479A (ja) 2003-02-25
CA2380452A1 (en) 2001-03-01

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)