GB9726229D0 - Resolution of chiral amines - Google Patents

Resolution of chiral amines

Info

Publication number
GB9726229D0
GB9726229D0 GBGB9726229.9A GB9726229A GB9726229D0 GB 9726229 D0 GB9726229 D0 GB 9726229D0 GB 9726229 A GB9726229 A GB 9726229A GB 9726229 D0 GB9726229 D0 GB 9726229D0
Authority
GB
United Kingdom
Prior art keywords
enantiomer
chiral amines
resolution
ester
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9726229.9A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Priority to GBGB9726229.9A priority Critical patent/GB9726229D0/en
Publication of GB9726229D0 publication Critical patent/GB9726229D0/en
Priority to AU14959/99A priority patent/AU1495999A/en
Priority to US09/555,924 priority patent/US6335187B1/en
Priority to AT98959022T priority patent/ATE233324T1/de
Priority to DE69811723T priority patent/DE69811723T2/de
Priority to EP98959022A priority patent/EP1036189B1/en
Priority to PCT/GB1998/003679 priority patent/WO1999031264A1/en
Priority to CA002313684A priority patent/CA2313684A1/en
Priority to JP2000539162A priority patent/JP2002508189A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Optical Integrated Circuits (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GBGB9726229.9A 1997-12-12 1997-12-12 Resolution of chiral amines Ceased GB9726229D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB9726229.9A GB9726229D0 (en) 1997-12-12 1997-12-12 Resolution of chiral amines
AU14959/99A AU1495999A (en) 1997-12-12 1998-12-09 Resolution of chiral amines
US09/555,924 US6335187B1 (en) 1997-12-12 1998-12-09 Resolution of chiral amines
AT98959022T ATE233324T1 (de) 1997-12-12 1998-12-09 Trennung von chiralen aminen
DE69811723T DE69811723T2 (de) 1997-12-12 1998-12-09 Trennung von chiralen aminen
EP98959022A EP1036189B1 (en) 1997-12-12 1998-12-09 Resolution of chiral amines
PCT/GB1998/003679 WO1999031264A1 (en) 1997-12-12 1998-12-09 Resolution of chiral amines
CA002313684A CA2313684A1 (en) 1997-12-12 1998-12-09 Resolution of chiral amines
JP2000539162A JP2002508189A (ja) 1997-12-12 1998-12-09 キラルアミン類の分離

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9726229.9A GB9726229D0 (en) 1997-12-12 1997-12-12 Resolution of chiral amines

Publications (1)

Publication Number Publication Date
GB9726229D0 true GB9726229D0 (en) 1998-02-11

Family

ID=10823474

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9726229.9A Ceased GB9726229D0 (en) 1997-12-12 1997-12-12 Resolution of chiral amines

Country Status (9)

Country Link
US (1) US6335187B1 (https=)
EP (1) EP1036189B1 (https=)
JP (1) JP2002508189A (https=)
AT (1) ATE233324T1 (https=)
AU (1) AU1495999A (https=)
CA (1) CA2313684A1 (https=)
DE (1) DE69811723T2 (https=)
GB (1) GB9726229D0 (https=)
WO (1) WO1999031264A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6624311B2 (en) 2000-10-27 2003-09-23 Bristol-Myers Squibb Pharma Company Enantioselective enzymatic aminolysis of a racemic 2-isoxazolylacetate alkyl ester
WO2003022785A2 (en) 2001-09-12 2003-03-20 Anormed Inc. Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
US7067291B2 (en) 2002-12-20 2006-06-27 Pfizer Inc. Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
KR100929437B1 (ko) 2007-08-02 2009-12-03 포항공과대학교 산학협력단 광학 활성을 갖는 아민의 제조방법
GB201020026D0 (en) 2010-11-25 2011-01-12 Cambrex Karlskoga Ab New process
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109069426B (zh) 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
PL3393468T3 (pl) 2015-12-22 2023-01-23 X4 Pharmaceuticals, Inc. Metody leczenia niedoboru odporności
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
WO2017223243A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
CN109234352A (zh) * 2018-10-30 2019-01-18 江苏理工学院 一种酶法拆分制备(r)-1-(1-萘基)乙胺的方法
CA3171250A1 (en) 2020-03-10 2021-09-16 E. Lynne KELLEY Methods for treating neutropenia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019002A1 (en) 1990-06-01 1991-12-12 Carlbiotech Ltd. A/S A process for chiral enrichment of asymmetric primary amines
DE4332738A1 (de) 1993-09-25 1995-03-30 Basf Ag Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung
DE19523151A1 (de) 1995-02-03 1996-08-14 Basf Ag Racematspaltung primärer und sekundärer heteroatomsubstituierter Amine durch Enzym-katalysierte Acylierung

Also Published As

Publication number Publication date
DE69811723D1 (de) 2003-04-03
DE69811723T2 (de) 2003-12-18
CA2313684A1 (en) 1999-06-24
EP1036189A1 (en) 2000-09-20
US6335187B1 (en) 2002-01-01
WO1999031264A1 (en) 1999-06-24
JP2002508189A (ja) 2002-03-19
ATE233324T1 (de) 2003-03-15
EP1036189B1 (en) 2003-02-26
AU1495999A (en) 1999-07-05

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)