DK1200601T3 - Fremgangsmåde til fremstilling af L-aminosyrer ud fra deres racemiske N-acetyl-D,L-derivater via enzymatisk racemat-spaltning ved hjælp af isolerede rekombinante enzymer - Google Patents

Fremgangsmåde til fremstilling af L-aminosyrer ud fra deres racemiske N-acetyl-D,L-derivater via enzymatisk racemat-spaltning ved hjælp af isolerede rekombinante enzymer

Info

Publication number
DK1200601T3
DK1200601T3 DK00943826T DK00943826T DK1200601T3 DK 1200601 T3 DK1200601 T3 DK 1200601T3 DK 00943826 T DK00943826 T DK 00943826T DK 00943826 T DK00943826 T DK 00943826T DK 1200601 T3 DK1200601 T3 DK 1200601T3
Authority
DK
Denmark
Prior art keywords
acetyl
amino acids
derivatives
racemic
preparation
Prior art date
Application number
DK00943826T
Other languages
English (en)
Inventor
Klaus Bartsch
Original Assignee
Bayer Cropscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Gmbh filed Critical Bayer Cropscience Gmbh
Application granted granted Critical
Publication of DK1200601T3 publication Critical patent/DK1200601T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK00943826T 1999-07-20 2000-06-17 Fremgangsmåde til fremstilling af L-aminosyrer ud fra deres racemiske N-acetyl-D,L-derivater via enzymatisk racemat-spaltning ved hjælp af isolerede rekombinante enzymer DK1200601T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19933362A DE19933362A1 (de) 1999-07-20 1999-07-20 Verfahren zur Herstellung von L-Aminosäuren aus ihren racemischen N-Acetyl-D,L-Derivaten durch enzymatische Racemat-Spaltung mittels isolierter, rekombinanter Enzyme

Publications (1)

Publication Number Publication Date
DK1200601T3 true DK1200601T3 (da) 2006-07-17

Family

ID=7915003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00943826T DK1200601T3 (da) 1999-07-20 2000-06-17 Fremgangsmåde til fremstilling af L-aminosyrer ud fra deres racemiske N-acetyl-D,L-derivater via enzymatisk racemat-spaltning ved hjælp af isolerede rekombinante enzymer

Country Status (24)

Country Link
US (1) US6686181B1 (da)
EP (1) EP1200601B1 (da)
JP (1) JP4723778B2 (da)
KR (1) KR100672146B1 (da)
CN (1) CN1175108C (da)
AT (1) ATE319836T1 (da)
AU (1) AU778206B2 (da)
BR (1) BR0012572A (da)
CA (1) CA2379849A1 (da)
CO (1) CO5310578A1 (da)
CZ (1) CZ2002224A3 (da)
DE (2) DE19933362A1 (da)
DK (1) DK1200601T3 (da)
ES (1) ES2258011T3 (da)
HU (1) HU229651B1 (da)
IL (1) IL147398A (da)
MX (1) MXPA02000623A (da)
NZ (1) NZ516710A (da)
PL (1) PL203870B1 (da)
RU (1) RU2270869C2 (da)
SK (1) SK402002A3 (da)
TW (1) TWI238193B (da)
UA (1) UA73743C2 (da)
WO (1) WO2001005982A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2287322A1 (en) * 2002-02-26 2011-02-23 Syngenta Limited A method of selectively producing male or female sterile plants
ES2391468T3 (es) * 2005-03-29 2012-11-27 Meiji Seika Pharma Co., Ltd. Procedimiento para la producción de ácido L-2-amino-4-(hidroximetilfosfinil)butanoico
WO2008029754A1 (fr) 2006-09-04 2008-03-13 Meiji Seika Kaisha, Ltd. Procédé de fabrication d'un acide aminophosphinylbutanoïque optiquement actif
EP2065391B1 (en) 2006-09-20 2014-06-18 Meiji Seika Pharma Co., Ltd. Method for producing phosphorus-containing a-amino acid and production intermediate thereof
WO2012154483A1 (en) * 2011-05-06 2012-11-15 Gilead Sciences, Inc. Dry powder fosfomycin/tobramycin formulation for inhalation
CN109988806B (zh) * 2017-12-29 2023-02-28 弈柯莱生物科技(上海)股份有限公司 一种n-乙酰-草铵膦盐的消旋方法
CN108690854B (zh) * 2018-04-16 2022-03-18 浙江工业大学 一种利用化学-酶法生产l-草铵膦的方法
BR112023026056A2 (pt) * 2021-06-11 2024-03-05 Upl Ltd Um método para obter l-glufosinato

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5547630A (en) * 1978-10-02 1980-04-04 Meiji Seika Kaisha Ltd Optical resolution of phosphorus-containing amino acid
US5081024A (en) * 1988-09-05 1992-01-14 Nissan Chemical Industries, Ltd. Process for producing optically active amino acids
DE4308061A1 (de) * 1993-03-13 1994-09-15 Hoechst Ag Neue Aminosäure-Deacetylase mit Spezifität für L-N-Acetyl-Phosphinothricin, ihre Herstellung und Verwendung
DE4422045A1 (de) * 1994-06-26 1996-01-04 Hoechst Schering Agrevo Gmbh Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten
WO1997041214A1 (en) * 1996-04-25 1997-11-06 Novartis Ag Biocatalysts with amine acylase activity
DE19652284A1 (de) * 1996-12-16 1998-06-18 Hoechst Schering Agrevo Gmbh Neue Gene codierend für Aminosäure-Deacetylasen mit Spezifität für N-Acetyl-L-Phosphinothricin, ihre Isolierung und Verwendung

Also Published As

Publication number Publication date
DE19933362A1 (de) 2001-02-08
WO2001005982A1 (de) 2001-01-25
HU229651B1 (hu) 2014-03-28
AU778206B2 (en) 2004-11-25
PL357347A1 (en) 2004-07-26
TWI238193B (en) 2005-08-21
CZ2002224A3 (cs) 2002-06-12
HUP0201850A3 (en) 2005-01-28
BR0012572A (pt) 2002-04-16
RU2270869C2 (ru) 2006-02-27
UA73743C2 (en) 2005-09-15
DE50012368D1 (de) 2006-05-04
CA2379849A1 (en) 2001-01-25
NZ516710A (en) 2002-11-26
EP1200601B1 (de) 2006-03-08
HUP0201850A2 (en) 2002-09-28
US6686181B1 (en) 2004-02-03
ATE319836T1 (de) 2006-03-15
MXPA02000623A (es) 2002-07-02
ES2258011T3 (es) 2006-08-16
IL147398A0 (en) 2002-08-14
IL147398A (en) 2005-12-18
SK402002A3 (en) 2002-04-04
KR20020020943A (ko) 2002-03-16
KR100672146B1 (ko) 2007-01-19
JP4723778B2 (ja) 2011-07-13
CO5310578A1 (es) 2003-08-29
CN1371422A (zh) 2002-09-25
EP1200601A1 (de) 2002-05-02
JP2003505031A (ja) 2003-02-12
PL203870B1 (pl) 2009-11-30
CN1175108C (zh) 2004-11-10
AU5815600A (en) 2001-02-05

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