DE69811723D1 - Trennung von chiralen aminen - Google Patents
Trennung von chiralen aminenInfo
- Publication number
- DE69811723D1 DE69811723D1 DE69811723T DE69811723T DE69811723D1 DE 69811723 D1 DE69811723 D1 DE 69811723D1 DE 69811723 T DE69811723 T DE 69811723T DE 69811723 T DE69811723 T DE 69811723T DE 69811723 D1 DE69811723 D1 DE 69811723D1
- Authority
- DE
- Germany
- Prior art keywords
- enantiomer
- chiral amines
- separation
- ester
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Optical Integrated Circuits (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9726229.9A GB9726229D0 (en) | 1997-12-12 | 1997-12-12 | Resolution of chiral amines |
PCT/GB1998/003679 WO1999031264A1 (en) | 1997-12-12 | 1998-12-09 | Resolution of chiral amines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69811723D1 true DE69811723D1 (de) | 2003-04-03 |
DE69811723T2 DE69811723T2 (de) | 2003-12-18 |
Family
ID=10823474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69811723T Expired - Fee Related DE69811723T2 (de) | 1997-12-12 | 1998-12-09 | Trennung von chiralen aminen |
Country Status (9)
Country | Link |
---|---|
US (1) | US6335187B1 (de) |
EP (1) | EP1036189B1 (de) |
JP (1) | JP2002508189A (de) |
AT (1) | ATE233324T1 (de) |
AU (1) | AU1495999A (de) |
CA (1) | CA2313684A1 (de) |
DE (1) | DE69811723T2 (de) |
GB (1) | GB9726229D0 (de) |
WO (1) | WO1999031264A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6624311B2 (en) | 2000-10-27 | 2003-09-23 | Bristol-Myers Squibb Pharma Company | Enantioselective enzymatic aminolysis of a racemic 2-isoxazolylacetate alkyl ester |
WO2003022785A2 (en) * | 2001-09-12 | 2003-03-20 | Anormed Inc. | Synthesis of enantiomerically pure amino-substituted fused bicyclic rings |
US7067291B2 (en) | 2002-12-20 | 2006-06-27 | Pfizer Inc. | Biocatalytic preparation of enantiomerically enriched aminopentanenitrile |
KR100929437B1 (ko) | 2007-08-02 | 2009-12-03 | 포항공과대학교 산학협력단 | 광학 활성을 갖는 아민의 제조방법 |
GB201020026D0 (en) | 2010-11-25 | 2011-01-12 | Cambrex Karlskoga Ab | New process |
CN109069426B (zh) | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
DK3393468T3 (da) | 2015-12-22 | 2022-12-19 | X4 Pharmaceuticals Inc | Fremgangsmåder til behandling af en immundefektsygdom |
JP2019510785A (ja) | 2016-04-08 | 2019-04-18 | エックス4 ファーマシューティカルズ, インコーポレイテッド | 癌を処置する方法 |
ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
JP7084624B2 (ja) | 2016-06-21 | 2022-06-15 | エックス4 ファーマシューティカルズ, インコーポレイテッド | Cxcr4阻害剤およびその使用 |
US11332470B2 (en) | 2016-06-21 | 2022-05-17 | X4 Pharmaceuticals, Inc. | CXCR4 inhibitors and uses thereof |
US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
CN109234352A (zh) * | 2018-10-30 | 2019-01-18 | 江苏理工学院 | 一种酶法拆分制备(r)-1-(1-萘基)乙胺的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991019002A1 (en) | 1990-06-01 | 1991-12-12 | Carlbiotech Ltd. A/S | A process for chiral enrichment of asymmetric primary amines |
DE4332738A1 (de) | 1993-09-25 | 1995-03-30 | Basf Ag | Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung |
DE19523151A1 (de) * | 1995-02-03 | 1996-08-14 | Basf Ag | Racematspaltung primärer und sekundärer heteroatomsubstituierter Amine durch Enzym-katalysierte Acylierung |
-
1997
- 1997-12-12 GB GBGB9726229.9A patent/GB9726229D0/en not_active Ceased
-
1998
- 1998-12-09 DE DE69811723T patent/DE69811723T2/de not_active Expired - Fee Related
- 1998-12-09 AU AU14959/99A patent/AU1495999A/en not_active Abandoned
- 1998-12-09 CA CA002313684A patent/CA2313684A1/en not_active Abandoned
- 1998-12-09 US US09/555,924 patent/US6335187B1/en not_active Expired - Fee Related
- 1998-12-09 JP JP2000539162A patent/JP2002508189A/ja not_active Withdrawn
- 1998-12-09 AT AT98959022T patent/ATE233324T1/de not_active IP Right Cessation
- 1998-12-09 WO PCT/GB1998/003679 patent/WO1999031264A1/en active IP Right Grant
- 1998-12-09 EP EP98959022A patent/EP1036189B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1999031264A1 (en) | 1999-06-24 |
DE69811723T2 (de) | 2003-12-18 |
ATE233324T1 (de) | 2003-03-15 |
EP1036189B1 (de) | 2003-02-26 |
GB9726229D0 (en) | 1998-02-11 |
EP1036189A1 (de) | 2000-09-20 |
US6335187B1 (en) | 2002-01-01 |
CA2313684A1 (en) | 1999-06-24 |
JP2002508189A (ja) | 2002-03-19 |
AU1495999A (en) | 1999-07-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |