GB967594A - 2-(2,6-dimethyl-3-hydroxy-4-tert-butyl-benzyl)-2-imidazoline,and acid addition salts thereof,and process for their manufacture - Google Patents
2-(2,6-dimethyl-3-hydroxy-4-tert-butyl-benzyl)-2-imidazoline,and acid addition salts thereof,and process for their manufactureInfo
- Publication number
- GB967594A GB967594A GB32237/61A GB3223761A GB967594A GB 967594 A GB967594 A GB 967594A GB 32237/61 A GB32237/61 A GB 32237/61A GB 3223761 A GB3223761 A GB 3223761A GB 967594 A GB967594 A GB 967594A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tert
- dimethyl
- hydroxy
- acid addition
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 6
- 150000003839 salts Chemical class 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000006114 decarboxylation reaction Methods 0.000 abstract 2
- 239000007923 nasal drop Substances 0.000 abstract 2
- 229940100662 nasal drops Drugs 0.000 abstract 2
- 239000007922 nasal spray Substances 0.000 abstract 2
- 229940097496 nasal spray Drugs 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229940073608 benzyl chloride Drugs 0.000 abstract 1
- 150000005524 benzylchlorides Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- KXZJHVJKXJLBKO-UHFFFAOYSA-N chembl1408157 Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=CC=1C1=CC=C(O)C=C1 KXZJHVJKXJLBKO-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000007265 chloromethylation reaction Methods 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000005526 vasoconstrictor agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEM46696A DE1117588B (de) | 1960-09-30 | 1960-09-30 | Verfahren zur Herstellung eines neuen Imidazolinderivates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB967594A true GB967594A (en) | 1964-08-26 |
Family
ID=7305675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32237/61A Expired GB967594A (en) | 1960-09-30 | 1961-09-07 | 2-(2,6-dimethyl-3-hydroxy-4-tert-butyl-benzyl)-2-imidazoline,and acid addition salts thereof,and process for their manufacture |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE608675A (enrdf_load_stackoverflow) |
| CH (1) | CH413848A (enrdf_load_stackoverflow) |
| DE (1) | DE1117588B (enrdf_load_stackoverflow) |
| FR (1) | FR1170M (enrdf_load_stackoverflow) |
| GB (1) | GB967594A (enrdf_load_stackoverflow) |
| SE (1) | SE306088B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099651A1 (de) * | 2005-03-24 | 2006-09-28 | Unipack Ges.M.B.H. | Flüssige, wässrige darreichungsform für sublinguale oder nasale anwendungen von aminorgruppen aufweisenden wirkstoffen |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120225918A1 (en) | 2011-03-03 | 2012-09-06 | Voom, Llc | Compositions and Methods for Non-Surgical Treatment of Ptosis |
| WO2014158118A1 (en) | 2013-03-29 | 2014-10-02 | Santa Farma İlaç Sanayi̇ A.Ş. | Suspension composition containing ipratropium and oxymetazoline |
| EP2978407B1 (en) | 2013-03-29 | 2020-05-06 | Santa Farma Ilaç Sanayi A.S. | Aqueous solution composition containing ipratropium and oxymetazoline |
| US11779553B1 (en) | 2022-11-28 | 2023-10-10 | Atif B. D. Collins | Methods and devices for treatment of eyelid ptosis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1049387B (de) * | 1959-01-29 | Ciba Aktiengesellschaft, Basel (Schweiz) | Verfahren zur Herstellung eines neuen Imidazolins |
-
1960
- 1960-09-30 DE DEM46696A patent/DE1117588B/de active Pending
-
1961
- 1961-05-25 FR FR862827A patent/FR1170M/fr active Active
- 1961-07-11 CH CH811861A patent/CH413848A/de unknown
- 1961-09-07 GB GB32237/61A patent/GB967594A/en not_active Expired
- 1961-09-27 SE SE9563/61A patent/SE306088B/xx unknown
- 1961-09-29 BE BE608675A patent/BE608675A/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099651A1 (de) * | 2005-03-24 | 2006-09-28 | Unipack Ges.M.B.H. | Flüssige, wässrige darreichungsform für sublinguale oder nasale anwendungen von aminorgruppen aufweisenden wirkstoffen |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1117588B (de) | 1961-11-23 |
| FR1170M (fr) | 1962-03-05 |
| BE608675A (fr) | 1962-03-29 |
| CH413848A (de) | 1966-05-31 |
| SE306088B (enrdf_load_stackoverflow) | 1968-11-18 |
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