GB947495A - New derivatives of dialkyl xanthines and the preparation thereof - Google Patents
New derivatives of dialkyl xanthines and the preparation thereofInfo
- Publication number
- GB947495A GB947495A GB14252/60A GB1425260A GB947495A GB 947495 A GB947495 A GB 947495A GB 14252/60 A GB14252/60 A GB 14252/60A GB 1425260 A GB1425260 A GB 1425260A GB 947495 A GB947495 A GB 947495A
- Authority
- GB
- United Kingdom
- Prior art keywords
- preparation
- xanthines
- hydroxyalkyl
- radical
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title abstract 2
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000009090 positive inotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14252/60A GB947495A (en) | 1960-04-22 | 1960-04-22 | New derivatives of dialkyl xanthines and the preparation thereof |
| BE602888A BE602888A (fr) | 1960-04-22 | 1961-04-21 | Nouveaux dérivés de 8-benzylxanthines et leur préparation. |
| LU40045A LU40045A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1960-04-22 | 1961-04-21 | |
| CH471861A CH401070A (fr) | 1960-04-22 | 1961-04-21 | Procédé de préparation de dérivés de 8-benzyl-1.3-dialcoyl-xanthines |
| FR859508A FR1124M (fr) | 1960-04-22 | 1961-04-21 | Nouveaux dérivés de 8-benzylxanthines. |
| ES0266788A ES266788A1 (es) | 1960-04-22 | 1961-04-21 | Un procedimiento de preparar un derivado de 8-bencil dialcohil xantina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB14252/60A GB947495A (en) | 1960-04-22 | 1960-04-22 | New derivatives of dialkyl xanthines and the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB947495A true GB947495A (en) | 1964-01-22 |
Family
ID=10037786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB14252/60A Expired GB947495A (en) | 1960-04-22 | 1960-04-22 | New derivatives of dialkyl xanthines and the preparation thereof |
Country Status (6)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011399A1 (en) * | 1978-11-11 | 1980-05-28 | FISONS plc | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them |
| US6117998A (en) * | 1996-11-19 | 2000-09-12 | Link Technology Incorporated | A1 adenosine receptor antagonists |
| US7202252B2 (en) | 2003-02-19 | 2007-04-10 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US7247639B2 (en) | 2003-06-06 | 2007-07-24 | Endacea, Inc. | A1 adenosine receptor antagonists |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3120909C2 (de) * | 1980-06-05 | 1986-01-02 | A. Christiaens S.A., Brüssel/Bruxelles | Verfahren zur Herstellung von 7-(N-Äthyl-N-β-hydroxyäthylaminoäthyl)-8-benzyltheophyllin (Bamifyllin) |
| BE1006613A3 (fr) * | 1993-01-21 | 1994-11-03 | Nycomed Christiaens Nv Sa | Procede de conversion de cycle xanthine ou derives de cycle xanthine en derives de type dialkylamino-xanthine. |
-
1960
- 1960-04-22 GB GB14252/60A patent/GB947495A/en not_active Expired
-
1961
- 1961-04-21 CH CH471861A patent/CH401070A/fr unknown
- 1961-04-21 BE BE602888A patent/BE602888A/fr unknown
- 1961-04-21 LU LU40045A patent/LU40045A1/xx unknown
- 1961-04-21 ES ES0266788A patent/ES266788A1/es not_active Expired
- 1961-04-21 FR FR859508A patent/FR1124M/fr not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011399A1 (en) * | 1978-11-11 | 1980-05-28 | FISONS plc | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them |
| US6117998A (en) * | 1996-11-19 | 2000-09-12 | Link Technology Incorporated | A1 adenosine receptor antagonists |
| US6489332B1 (en) | 1996-11-19 | 2002-12-03 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US6495687B1 (en) | 1996-11-19 | 2002-12-17 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US7202252B2 (en) | 2003-02-19 | 2007-04-10 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US7423041B2 (en) | 2003-02-19 | 2008-09-09 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US7247639B2 (en) | 2003-06-06 | 2007-07-24 | Endacea, Inc. | A1 adenosine receptor antagonists |
| US7902360B2 (en) | 2003-06-06 | 2011-03-08 | Wilson Constance N | A1 adenosine receptor antagonists |
Also Published As
| Publication number | Publication date |
|---|---|
| CH401070A (fr) | 1965-10-31 |
| FR1124M (fr) | 1962-02-12 |
| ES266788A1 (es) | 1961-11-01 |
| LU40045A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1961-10-21 |
| BE602888A (fr) | 1961-10-23 |
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