GB942226A - Article and the preparation thereof - Google Patents

Article and the preparation thereof

Info

Publication number
GB942226A
GB942226A GB3826561A GB3826561A GB942226A GB 942226 A GB942226 A GB 942226A GB 3826561 A GB3826561 A GB 3826561A GB 3826561 A GB3826561 A GB 3826561A GB 942226 A GB942226 A GB 942226A
Authority
GB
United Kingdom
Prior art keywords
collagen
mass
acid
dispersion
series
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3826561A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of GB942226A publication Critical patent/GB942226A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A method of making a collagen sponge, having interconnected pores, comprises freezing an aqueous dispersion of collagen fibres, removing the water by immersing the frozen mass in a water-miscible, dehydrating solvent, and drying the resulting collagen mass. The dehydrating bath contains sufficient quantity of a base, such as ammonium hydroxide, to neutralize the acid present in the collagen dispersion. In one example, cattle tendon is cleaned and sliced and then treated with an enzyme solution to dissolve elastin. It is then swollen by the addition of cyano-acetic acid and forced through a series of screens. After being frozen in steel moulds the blocks are removed and immersed in a series of baths of isopropanol containing a small proportion of ammonium hydroxide, to dehydrate the mass, which is finally air dried. Acetic acid, cyanoacetic acid and lactic acid are referred to as suitable for use in producing the collagen dispersion and either acetone or isopropanol may be used for dehydration.
GB3826561A 1960-10-25 1961-10-25 Article and the preparation thereof Expired GB942226A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6470360A 1960-10-25 1960-10-25

Publications (1)

Publication Number Publication Date
GB942226A true GB942226A (en) 1963-11-20

Family

ID=22057741

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3826561A Expired GB942226A (en) 1960-10-25 1961-10-25 Article and the preparation thereof

Country Status (2)

Country Link
BR (1) BR6133695D0 (en)
GB (1) GB942226A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2108068A1 (en) * 1970-09-29 1972-05-12 Fmc Corp
FR2393581A1 (en) * 1977-06-09 1979-01-05 Pikok Ind Trading Co PROCESS FOR PREPARING A COLLAGEN-BASED DRESSING FOR THE SKIN, AND DRESSINGS OBTAINED
FR2449400A1 (en) * 1979-02-21 1980-09-19 Pfrimmer Pharma PROCESS FOR OBTAINING STOCKABLE GRAFTS
EP0419111A1 (en) * 1989-09-15 1991-03-27 Organogenesis Inc. Collagen compositions and methods for preparation thereof
EP2459244A1 (en) * 2009-07-27 2012-06-06 National Cheng Kung University Method for preparing porous collagen matrices
CN105343928A (en) * 2015-11-30 2016-02-24 江南大学 Technology for preparing collagen sponge

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2108068A1 (en) * 1970-09-29 1972-05-12 Fmc Corp
FR2393581A1 (en) * 1977-06-09 1979-01-05 Pikok Ind Trading Co PROCESS FOR PREPARING A COLLAGEN-BASED DRESSING FOR THE SKIN, AND DRESSINGS OBTAINED
FR2449400A1 (en) * 1979-02-21 1980-09-19 Pfrimmer Pharma PROCESS FOR OBTAINING STOCKABLE GRAFTS
US4300243A (en) * 1979-02-21 1981-11-17 Pfrimmer & Co., Pharmazeutische Werke Erlangen Gmbh Process for the preparation of preserved transplants
EP0419111A1 (en) * 1989-09-15 1991-03-27 Organogenesis Inc. Collagen compositions and methods for preparation thereof
EP2459244A1 (en) * 2009-07-27 2012-06-06 National Cheng Kung University Method for preparing porous collagen matrices
EP2459244A4 (en) * 2009-07-27 2012-12-19 Univ Nat Cheng Kung Method for preparing porous collagen matrices
CN105343928A (en) * 2015-11-30 2016-02-24 江南大学 Technology for preparing collagen sponge

Also Published As

Publication number Publication date
BR6133695D0 (en) 1973-06-14

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