GB934712A - New steroid compounds and processes for the production thereof - Google Patents
New steroid compounds and processes for the production thereofInfo
- Publication number
- GB934712A GB934712A GB1645062A GB1645062A GB934712A GB 934712 A GB934712 A GB 934712A GB 1645062 A GB1645062 A GB 1645062A GB 1645062 A GB1645062 A GB 1645062A GB 934712 A GB934712 A GB 934712A
- Authority
- GB
- United Kingdom
- Prior art keywords
- positions
- pregn
- processes
- represent
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises 16-methyl-pregn-11-one derivatives having the formula: <FORM:0934712/IV(a)/1> where R and R1 both designate either the ketonic oxygen atom =O or the residue of a cyclic ketal grouping and X and Y either can represent a double bond between the 16- and 17-positions or alternatively in the case when R and r1 both represent cyclic ketal groups, may also represent an epoxide link between the 16- and 17-positions and processes for the production thereof by condensing pregn-16-en-3,11,20-trione with diazomethane in an inert organic solvent to form the corresponding 16,17-pyrazoline and heating the latter in a high boiling point solvent. Subsequently ketalisation may be effected at the 3- and 20-positions to form 3,20-diketal of 16-methyl-pregn-16-en-3,11,20-trione, which may be epoxidised, e.g. with a peracid at the 16,17-positions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR784845A FR1234733A (en) | 1959-01-23 | 1959-01-23 | Process for preparing 16 alpha-methyl pregnane-diones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB934712A true GB934712A (en) | 1963-08-21 |
Family
ID=8710465
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB243560A Expired GB934703A (en) | 1959-01-23 | 1960-01-22 | Processes for the production of steroid compounds |
| GB1645062A Expired GB934712A (en) | 1959-01-23 | 1960-01-22 | New steroid compounds and processes for the production thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB243560A Expired GB934703A (en) | 1959-01-23 | 1960-01-22 | Processes for the production of steroid compounds |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE586857A (en) |
| CH (1) | CH369757A (en) |
| ES (1) | ES255202A1 (en) |
| FR (1) | FR1234733A (en) |
| GB (2) | GB934703A (en) |
-
1959
- 1959-01-23 FR FR784845A patent/FR1234733A/en not_active Expired
-
1960
- 1960-01-06 CH CH3860A patent/CH369757A/en unknown
- 1960-01-22 ES ES0255202A patent/ES255202A1/en not_active Expired
- 1960-01-22 GB GB243560A patent/GB934703A/en not_active Expired
- 1960-01-22 GB GB1645062A patent/GB934712A/en not_active Expired
- 1960-01-22 BE BE586857A patent/BE586857A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1234733A (en) | 1960-10-19 |
| CH369757A (en) | 1963-06-15 |
| GB934703A (en) | 1963-08-21 |
| BE586857A (en) | 1960-07-22 |
| ES255202A1 (en) | 1960-11-16 |
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