GB914785A - Piperidine ester derivative - Google Patents

Piperidine ester derivative

Info

Publication number
GB914785A
GB914785A GB1435959A GB1435959A GB914785A GB 914785 A GB914785 A GB 914785A GB 1435959 A GB1435959 A GB 1435959A GB 1435959 A GB1435959 A GB 1435959A GB 914785 A GB914785 A GB 914785A
Authority
GB
United Kingdom
Prior art keywords
general formula
carbon atoms
acid addition
ester derivative
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1435959A
Inventor
Jany Renz
Jean-Pierre Bourquin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Priority to GB1435959A priority Critical patent/GB914785A/en
Publication of GB914785A publication Critical patent/GB914785A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Abstract

The invention comprises compounds of the general formula <FORM:0914785/IV (b)/1> together with their acid addition salts, wherein R1 is a C1-4 alkyl group, X is O or NH, A is a straight chain alkylene group containing not more than 3 carbon atoms, R2 is hydrogen, halogen or an O-alkyl group having 1-4 carbon atoms; the preparation thereof by reacting a 1-alkyl-4-hydroxypiperidine derivative of the general formula <FORM:0914785/IV (b)/2> with a benzoic acid derivative having the general formula <FORM:0914785/IV (b)/3> where Z is chlorine, bromine or a C1-3 alkoxy group, preferably carried out in the presence of a condensation agent, and pharmaceutical compositions, useful as local anesthetics, which comprise the esters or an acid addition salt thereof together with an inert carrier.
GB1435959A 1959-04-27 1959-04-27 Piperidine ester derivative Expired GB914785A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1435959A GB914785A (en) 1959-04-27 1959-04-27 Piperidine ester derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1435959A GB914785A (en) 1959-04-27 1959-04-27 Piperidine ester derivative

Publications (1)

Publication Number Publication Date
GB914785A true GB914785A (en) 1963-01-02

Family

ID=10039777

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1435959A Expired GB914785A (en) 1959-04-27 1959-04-27 Piperidine ester derivative

Country Status (1)

Country Link
GB (1) GB914785A (en)

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