GB932017A - Improvements in or relating to 3-mercaptophenothiazines - Google Patents

Improvements in or relating to 3-mercaptophenothiazines

Info

Publication number
GB932017A
GB932017A GB3054560A GB3054560A GB932017A GB 932017 A GB932017 A GB 932017A GB 3054560 A GB3054560 A GB 3054560A GB 3054560 A GB3054560 A GB 3054560A GB 932017 A GB932017 A GB 932017A
Authority
GB
United Kingdom
Prior art keywords
alkyl
pyrrolidyl
hal
alkyl group
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3054560A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB932017A publication Critical patent/GB932017A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of the general formula: <FORM:0932017/IV(a)/1> and their acid addition salts, wherein R1 represents a C1-C4 alkyl group, and R2 a 1-alkyl-pyrrolidyl-(2), 1-alkyl-pyrrolidyl-(3) or a 1-alkyl-piperidyl-(2) in which each alkyl group contains 1-4 carbon atoms, the preparation thereof by reacting an appropriate 3-mercaptopphenothiazine with a haloalkylamine Hal-CH2-R2 wherein Hal represents a chlorine, bromine or iodine atom, and pharmaceutical compositions (having drug-potentiating and, in some cases, anti-histaminic, adrenaline inhibiting or sedative activity) comprising the compounds of the invention together with an inert carrier. Specifications 863,547 and 863,550 are referred to.
GB3054560A 1959-11-27 1960-09-05 Improvements in or relating to 3-mercaptophenothiazines Expired GB932017A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH8115759A CH378324A (en) 1959-11-27 1959-11-27 Process for the preparation of new phenothiazine derivatives

Publications (1)

Publication Number Publication Date
GB932017A true GB932017A (en) 1963-07-24

Family

ID=4538536

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3054560A Expired GB932017A (en) 1959-11-27 1960-09-05 Improvements in or relating to 3-mercaptophenothiazines

Country Status (6)

Country Link
CH (1) CH378324A (en)
DE (1) DE1156079B (en)
ES (1) ES262783A1 (en)
FI (1) FI40541B (en)
GB (1) GB932017A (en)
NL (1) NL258363A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299217B1 (en) 1996-03-21 2001-10-09 Kikuo Saito Flexible pipe connector

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT199191B (en) * 1957-02-22 1958-08-25 Sandoz Ag Process for the preparation of new mercapto-phenothiazine derivatives substituted in the 3-position

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299217B1 (en) 1996-03-21 2001-10-09 Kikuo Saito Flexible pipe connector

Also Published As

Publication number Publication date
ES262783A1 (en) 1961-06-01
FI40541B (en) 1968-11-30
NL258363A (en)
DE1156079B (en) 1963-10-24
CH378324A (en) 1964-06-15

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