GB890732A - Improvements in or relating to diphenylamines - Google Patents

Improvements in or relating to diphenylamines

Info

Publication number
GB890732A
GB890732A GB20753/58A GB2075358A GB890732A GB 890732 A GB890732 A GB 890732A GB 20753/58 A GB20753/58 A GB 20753/58A GB 2075358 A GB2075358 A GB 2075358A GB 890732 A GB890732 A GB 890732A
Authority
GB
United Kingdom
Prior art keywords
phenyl
acid
alkylmercapto
iodo
aniline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20753/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WESTMINSTER BANK Ltd
Original Assignee
WESTMINSTER BANK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WESTMINSTER BANK Ltd filed Critical WESTMINSTER BANK Ltd
Publication of GB890732A publication Critical patent/GB890732A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0890732/IV (b)/1> where R1 represents n-alkyl having from 3 to 6 carbon atoms, or phenyl, and R2 represents an alkyl group having 1 to 4 carbon atoms, and acid addition salts thereof; and the preparation thereof by reacting a compound of the general formula <FORM:0890732/IV (b)/2> with a compound of the general formula <FORM:0890732/IV (b)/3> where X represents chlorine, bromine or iodine, preferably in the presence of an alkaline condensing agent and, if desired, converting the products into salts by reaction with acids in alcoholic solution. The products have pharmacodyanamic and fungicidal properties. N-(m-Alkylmercapto-phenyl)-anilines (II) are prepared by reacting m-alkylmercapto-anilines, obtained by stannous chloride-hydrochloric acid reduction of the corresponding nitro compound, with the potassium salt of o-chlorobenzoic acid and decarboxylating the resulting N-(m-alkylmercapto-phenyl)-anthranilic acid. N-(m-phenylmercapto-phenyl)-aniline is prepared by condensing m-iodo-aniline with the potassium salt of o-chloro-benzoic acid, decarboxylating the resulting N-(m-iodo-phenyl)-anthranilic acid to form N-(m-iodo-phenyl)-aniline and reacting this with sodium thiophenolate.
GB20753/58A 1957-07-19 1958-06-27 Improvements in or relating to diphenylamines Expired GB890732A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH890732X 1957-07-19

Publications (1)

Publication Number Publication Date
GB890732A true GB890732A (en) 1962-03-07

Family

ID=4545736

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20753/58A Expired GB890732A (en) 1957-07-19 1958-06-27 Improvements in or relating to diphenylamines

Country Status (1)

Country Link
GB (1) GB890732A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9862679B2 (en) 2013-03-08 2018-01-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US11365195B2 (en) 2017-11-13 2022-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Atypical inhibitors of monoamine transporters; method of making; and use thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9862679B2 (en) 2013-03-08 2018-01-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US10590074B2 (en) 2013-03-08 2020-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US10913711B2 (en) 2013-03-08 2021-02-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US11555013B2 (en) 2013-03-08 2023-01-17 The Usa, As Represented By The Secretary, Dhhs Potent and selective inhibitors of monoamine transporters; method of making; and use thereof
US11365195B2 (en) 2017-11-13 2022-06-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Atypical inhibitors of monoamine transporters; method of making; and use thereof

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