GB908282A - Coated pharmaceutical granules and tablets thereof - Google Patents
Coated pharmaceutical granules and tablets thereofInfo
- Publication number
- GB908282A GB908282A GB523358A GB523358A GB908282A GB 908282 A GB908282 A GB 908282A GB 523358 A GB523358 A GB 523358A GB 523358 A GB523358 A GB 523358A GB 908282 A GB908282 A GB 908282A
- Authority
- GB
- United Kingdom
- Prior art keywords
- granules
- coated
- tabletted
- medicament
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008187 granular material Substances 0.000 title abstract 15
- 239000003814 drug Substances 0.000 abstract 4
- CPJSUEIXXCENMM-UHFFFAOYSA-N phenacetin Chemical compound CCOC1=CC=C(NC(C)=O)C=C1 CPJSUEIXXCENMM-UHFFFAOYSA-N 0.000 abstract 4
- 239000000126 substance Substances 0.000 abstract 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 3
- 229930006000 Sucrose Natural products 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000005720 sucrose Substances 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 2
- 239000001856 Ethyl cellulose Substances 0.000 abstract 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 2
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 230000001079 digestive effect Effects 0.000 abstract 2
- 229920001249 ethyl cellulose Polymers 0.000 abstract 2
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 239000008101 lactose Substances 0.000 abstract 2
- 229940113116 polyethylene glycol 1000 Drugs 0.000 abstract 2
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 abstract 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 abstract 1
- 239000001836 Dioctyl sodium sulphosuccinate Substances 0.000 abstract 1
- BALXUFOVQVENIU-GNAZCLTHSA-N Ephedrine hydrochloride Chemical compound Cl.CN[C@@H](C)[C@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-GNAZCLTHSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000001506 calcium phosphate Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 229920002301 cellulose acetate Polymers 0.000 abstract 1
- 229920003086 cellulose ether Polymers 0.000 abstract 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 abstract 1
- 229940038472 dicalcium phosphate Drugs 0.000 abstract 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 235000019329 dioctyl sodium sulphosuccinate Nutrition 0.000 abstract 1
- 229960002534 ephedrine hydrochloride Drugs 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 abstract 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE575775D BE575775A (enrdf_load_stackoverflow) | 1958-02-18 | ||
| GB523358A GB908282A (en) | 1958-02-18 | 1958-02-18 | Coated pharmaceutical granules and tablets thereof |
| ES0247237A ES247237A1 (es) | 1958-02-18 | 1959-02-14 | UN MÉTODO PARA LA PREPARACION DE GRáNULOS DE ACCIoN PROLONGADA |
| BR10848459A BR5908484D0 (pt) | 1958-02-18 | 1959-02-16 | Aperfeicoamentos em ou relativos a preparacoes farmaceuticas |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB523358A GB908282A (en) | 1958-02-18 | 1958-02-18 | Coated pharmaceutical granules and tablets thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB908282A true GB908282A (en) | 1962-10-17 |
Family
ID=9792213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB523358A Expired GB908282A (en) | 1958-02-18 | 1958-02-18 | Coated pharmaceutical granules and tablets thereof |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE575775A (enrdf_load_stackoverflow) |
| BR (1) | BR5908484D0 (enrdf_load_stackoverflow) |
| ES (1) | ES247237A1 (enrdf_load_stackoverflow) |
| GB (1) | GB908282A (enrdf_load_stackoverflow) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4101651A (en) * | 1975-09-29 | 1978-07-18 | Meiji Seika Kaisha, Ltd. | Process for preparing preparations for oral administration |
| FR2385388A1 (enrdf_load_stackoverflow) * | 1977-04-01 | 1978-10-27 | Hoechst Ag | |
| FR2430766A1 (fr) * | 1978-07-15 | 1980-02-08 | Boehringer Sohn Ingelheim | Forme retard de medicaments, comportant une enveloppe de diffusion poreuse insoluble |
| EP0355247A3 (en) * | 1988-08-22 | 1990-12-12 | Ss Pharmaceutical Co., Ltd. | Compressed-molded preparations |
| GB2241168A (en) * | 1990-02-26 | 1991-08-28 | Int Medical Research Limited | Controlled release product containing salicylate |
| WO2005084457A1 (en) * | 2004-03-04 | 2005-09-15 | Goekhan Cem | Artificial fruit |
| EP1286662A4 (en) * | 2000-05-19 | 2009-08-05 | Yamanouchi Pharma Tech Inc | TABLETS AND METHODS FOR THE MODIFIED RELEASE OF HYDROPHILERS AND OTHER ACTIVE SUBSTANCES |
| CN110882281A (zh) * | 2019-11-30 | 2020-03-17 | 江苏艾兰得营养品有限公司 | 一种益生菌肠溶片剂及其制备方法 |
-
0
- BE BE575775D patent/BE575775A/xx unknown
-
1958
- 1958-02-18 GB GB523358A patent/GB908282A/en not_active Expired
-
1959
- 1959-02-14 ES ES0247237A patent/ES247237A1/es not_active Expired
- 1959-02-16 BR BR10848459A patent/BR5908484D0/pt unknown
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4101651A (en) * | 1975-09-29 | 1978-07-18 | Meiji Seika Kaisha, Ltd. | Process for preparing preparations for oral administration |
| FR2385388A1 (enrdf_load_stackoverflow) * | 1977-04-01 | 1978-10-27 | Hoechst Ag | |
| FR2430766A1 (fr) * | 1978-07-15 | 1980-02-08 | Boehringer Sohn Ingelheim | Forme retard de medicaments, comportant une enveloppe de diffusion poreuse insoluble |
| US4578264A (en) * | 1978-07-15 | 1986-03-25 | Boehringer Ingelheim Gmbh | Retard form of pharmaceuticals with insoluble porous diffusion coatings |
| US5186943A (en) * | 1988-08-22 | 1993-02-16 | Ss Pharmaceutical Co., Ltd. | Compressed-molded preparations |
| EP0355247A3 (en) * | 1988-08-22 | 1990-12-12 | Ss Pharmaceutical Co., Ltd. | Compressed-molded preparations |
| US5275825A (en) * | 1988-08-22 | 1994-01-04 | Ss Pharmaceutical Co., Ltd. | Compressed-molded preparations |
| US5156849A (en) * | 1990-02-26 | 1992-10-20 | Byrne Rynne Holdings Limited | Pharmaceutical composition |
| GB2241168A (en) * | 1990-02-26 | 1991-08-28 | Int Medical Research Limited | Controlled release product containing salicylate |
| EP1286662A4 (en) * | 2000-05-19 | 2009-08-05 | Yamanouchi Pharma Tech Inc | TABLETS AND METHODS FOR THE MODIFIED RELEASE OF HYDROPHILERS AND OTHER ACTIVE SUBSTANCES |
| WO2005084457A1 (en) * | 2004-03-04 | 2005-09-15 | Goekhan Cem | Artificial fruit |
| GB2427993A (en) * | 2004-03-04 | 2007-01-17 | Cem Goekhan | Artificial fruit |
| GB2427993B (en) * | 2004-03-04 | 2008-06-11 | Cem Goekhan | Low glycaemic index sugar |
| CN110882281A (zh) * | 2019-11-30 | 2020-03-17 | 江苏艾兰得营养品有限公司 | 一种益生菌肠溶片剂及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE575775A (enrdf_load_stackoverflow) | |
| ES247237A1 (es) | 1959-06-16 |
| BR5908484D0 (pt) | 1973-06-12 |
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