GB906245A - N-propargylbenzylamines and their preparation - Google Patents

N-propargylbenzylamines and their preparation

Info

Publication number
GB906245A
GB906245A GB2037960A GB2037960A GB906245A GB 906245 A GB906245 A GB 906245A GB 2037960 A GB2037960 A GB 2037960A GB 2037960 A GB2037960 A GB 2037960A GB 906245 A GB906245 A GB 906245A
Authority
GB
United Kingdom
Prior art keywords
preparation
propargyl
propargylbenzylamine
phenylethylamine
represents hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2037960A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of GB906245A publication Critical patent/GB906245A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises N-propargylbenzylamine, N-propargyl-a -phenylethylamine, their non-toxic salts, and a process for the preparation of compounds of the general formula:- <FORM:0906245/IV (b)/1> (in which one R represents hydrogen or methyl and the other represents hydrogen) by refluxing an amine C6H5.CHR.NHR with propargyl bromide in anhydrous ethanol and in the presence of a hydrohalide acceptor, e.g. anhydrous sodium carbonate, until the reaction is complete, removing the excess hydrohalide acceptor and ethanol, extracting the residue with dry ether and isolating the desired compound from the ethereal solution. Examples detail the preparation of N-propargylbenzylamine, its N-methyl derivative, N-propargyl-a -phenylethylamine and their hydrochloride salts.
GB2037960A 1959-06-10 1960-06-09 N-propargylbenzylamines and their preparation Expired GB906245A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81923859A 1959-06-10 1959-06-10

Publications (1)

Publication Number Publication Date
GB906245A true GB906245A (en) 1962-09-19

Family

ID=25227577

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2037960A Expired GB906245A (en) 1959-06-10 1960-06-09 N-propargylbenzylamines and their preparation

Country Status (3)

Country Link
BE (1) BE591650A (en)
FR (1) FR257M (en)
GB (1) GB906245A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342661A1 (en) * 1976-03-04 1977-09-30 Schering Ag PESTICIDE PRODUCTS CONTAINING PROPYNE-2 YL-AMINES

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342661A1 (en) * 1976-03-04 1977-09-30 Schering Ag PESTICIDE PRODUCTS CONTAINING PROPYNE-2 YL-AMINES

Also Published As

Publication number Publication date
BE591650A (en) 1960-10-03
FR257M (en) 1961-02-17

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