GB898590A - New octahydroindole derivatives - Google Patents
New octahydroindole derivativesInfo
- Publication number
- GB898590A GB898590A GB9703/61A GB970361A GB898590A GB 898590 A GB898590 A GB 898590A GB 9703/61 A GB9703/61 A GB 9703/61A GB 970361 A GB970361 A GB 970361A GB 898590 A GB898590 A GB 898590A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- new
- formula
- aralkylation
- alkylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Abstract
The invention comprises compounds of general formula <FORM:0898590/IV (b)/1> in which R1 is a phenyl radical which may be substituted by a halogen atom, a hydroxyl or alkyl group, or up to three times by an alkoxy group; and R2 is an alkyl or aralkyl group; also acid addition salts, optical isomers, and iso-compounds thereof; also processes for their preparation from compounds of formula <FORM:0898590/IV (b)/2> by alkylation or aralkylation of the nitrogen atom, or from compounds of formula <FORM:0898590/IV (b)/3> by alkylation or aralkylation of the nitrogen atom followed by hydrogenation, and, if desired, separation of the product into optical isomers and iso-compounds.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEB0057253 | 1960-03-28 | ||
DEB0057630 | 1960-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB898590A true GB898590A (en) | 1962-06-14 |
Family
ID=25965609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB9703/61A Expired GB898590A (en) | 1960-03-28 | 1961-03-16 | New octahydroindole derivatives |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE601654A (en) |
CH (1) | CH389609A (en) |
GB (1) | GB898590A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4042707A (en) * | 1976-02-19 | 1977-08-16 | E. I. Du Pont De Nemours And Company | 3α-Arylhydroisoindoles |
US4529736A (en) * | 1982-07-28 | 1985-07-16 | American Cyanamid Company | 3a-(Substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals |
-
1961
- 1961-03-16 GB GB9703/61A patent/GB898590A/en not_active Expired
- 1961-03-22 BE BE601654A patent/BE601654A/en unknown
- 1961-03-23 CH CH346061A patent/CH389609A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4042707A (en) * | 1976-02-19 | 1977-08-16 | E. I. Du Pont De Nemours And Company | 3α-Arylhydroisoindoles |
US4529736A (en) * | 1982-07-28 | 1985-07-16 | American Cyanamid Company | 3a-(Substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals |
Also Published As
Publication number | Publication date |
---|---|
CH389609A (en) | 1965-03-31 |
BE601654A (en) | 1961-09-22 |
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