GB898590A - New octahydroindole derivatives - Google Patents

New octahydroindole derivatives

Info

Publication number
GB898590A
GB898590A GB9703/61A GB970361A GB898590A GB 898590 A GB898590 A GB 898590A GB 9703/61 A GB9703/61 A GB 9703/61A GB 970361 A GB970361 A GB 970361A GB 898590 A GB898590 A GB 898590A
Authority
GB
United Kingdom
Prior art keywords
compounds
new
formula
aralkylation
alkylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9703/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB898590A publication Critical patent/GB898590A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Abstract

The invention comprises compounds of general formula <FORM:0898590/IV (b)/1> in which R1 is a phenyl radical which may be substituted by a halogen atom, a hydroxyl or alkyl group, or up to three times by an alkoxy group; and R2 is an alkyl or aralkyl group; also acid addition salts, optical isomers, and iso-compounds thereof; also processes for their preparation from compounds of formula <FORM:0898590/IV (b)/2> by alkylation or aralkylation of the nitrogen atom, or from compounds of formula <FORM:0898590/IV (b)/3> by alkylation or aralkylation of the nitrogen atom followed by hydrogenation, and, if desired, separation of the product into optical isomers and iso-compounds.
GB9703/61A 1960-03-28 1961-03-16 New octahydroindole derivatives Expired GB898590A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB0057253 1960-03-28
DEB0057630 1960-04-28

Publications (1)

Publication Number Publication Date
GB898590A true GB898590A (en) 1962-06-14

Family

ID=25965609

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9703/61A Expired GB898590A (en) 1960-03-28 1961-03-16 New octahydroindole derivatives

Country Status (3)

Country Link
BE (1) BE601654A (en)
CH (1) CH389609A (en)
GB (1) GB898590A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
US4529736A (en) * 1982-07-28 1985-07-16 American Cyanamid Company 3a-(Substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
US4529736A (en) * 1982-07-28 1985-07-16 American Cyanamid Company 3a-(Substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals

Also Published As

Publication number Publication date
CH389609A (en) 1965-03-31
BE601654A (en) 1961-09-22

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