GB1053843A - - Google Patents
Info
- Publication number
- GB1053843A GB1053843A GB1053843DA GB1053843A GB 1053843 A GB1053843 A GB 1053843A GB 1053843D A GB1053843D A GB 1053843DA GB 1053843 A GB1053843 A GB 1053843A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formula
- alkylamino
- sept
- ketone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002576 ketones Chemical class 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
- C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,053,843. Dibenzazulenes. KONINKLIJKE PHARMACEUTISCHE FABRIEKEN V/H BROCADES - STHEEMAN & PHARMACIA N.V. Sept. 16, 1964 [Sept. 16, 1963], No. 36436/63. Heading C2C. Compounds of the formula and non-toxic acid addition salts thereof. where X is -CH 2 -CH 2 - or -CH=CH-, R 1 and R 2 are each H, halogen or alkyl, and R 3 is amino, alkylamino, dialkylamino, phenyl (alkyl) amino, or N-alkyl-N-phenyl-alkylamino, are prepared by converting, by methods known per se, a compound of the formula wherein at least one of the 4- and 6-positions is unsubstituted, into a ketone of the formula and reducing the ketone in the presence of an amine HR 3 . Pharmaceutical compositions, useful as analgesics, contain the compounds of the invention and may be in standard forms for enteral and parenteral administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3643663 | 1963-09-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1053843A true GB1053843A (en) |
Family
ID=10388134
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1053844D Expired GB1053844A (en) | 1963-09-16 | ||
GB1053843D Active GB1053843A (en) | 1963-09-16 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1053844D Expired GB1053844A (en) | 1963-09-16 |
Country Status (3)
Country | Link |
---|---|
US (1) | US3358027A (en) |
BE (1) | BE653090A (en) |
GB (2) | GB1053843A (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3441567A (en) * | 1965-06-01 | 1969-04-29 | Sandoz Ag | Aminomethyldibenzobicycloalkenes |
US3502686A (en) * | 1966-04-14 | 1970-03-24 | Sandoz Ag | 2-hydroxy-dibenzazulene compounds |
US3624259A (en) * | 1966-04-14 | 1971-11-30 | Sandoz Ag | Tetracyclic compounds |
US3459806A (en) * | 1968-02-07 | 1969-08-05 | Sandoz Ag | Benzobenzazulenes |
US3526665A (en) * | 1968-02-07 | 1970-09-01 | Sandoz Ag | Benzobenzazulenes |
US3491150A (en) * | 1969-02-24 | 1970-01-20 | Sandoz Ag | Aminohydroxyhexahydrocyclopentadibenzocyclooctenes |
US4267192A (en) * | 1980-03-11 | 1981-05-12 | American Home Products Corporation | Method for treating inflammation |
AU2258683A (en) * | 1983-01-03 | 1984-07-05 | American Home Products Corporation | Dibenzocycloheptenylidenes and derivatives theof |
-
0
- GB GB1053844D patent/GB1053844A/en not_active Expired
- BE BE653090D patent/BE653090A/xx unknown
- GB GB1053843D patent/GB1053843A/en active Active
-
1964
- 1964-08-13 US US389471A patent/US3358027A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US3358027A (en) | 1967-12-12 |
BE653090A (en) | |
GB1053844A (en) | 1900-01-01 |
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