GB879901A - New water-insoluble salts of basic antihistaminics - Google Patents
New water-insoluble salts of basic antihistaminicsInfo
- Publication number
- GB879901A GB879901A GB22820/60A GB2282060A GB879901A GB 879901 A GB879901 A GB 879901A GB 22820/60 A GB22820/60 A GB 22820/60A GB 2282060 A GB2282060 A GB 2282060A GB 879901 A GB879901 A GB 879901A
- Authority
- GB
- United Kingdom
- Prior art keywords
- basic
- antihistaminics
- stearyl
- cetyl
- new water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001387 anti-histamine Effects 0.000 title abstract 3
- 239000000739 antihistaminic agent Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 229940125715 antihistaminic agent Drugs 0.000 title abstract 2
- HVWGGPRWKSHASF-UHFFFAOYSA-N Sulfuric acid, monooctadecyl ester Chemical class CCCCCCCCCCCCCCCCCCOS(O)(=O)=O HVWGGPRWKSHASF-UHFFFAOYSA-N 0.000 abstract 2
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000002191 fatty alcohols Chemical class 0.000 abstract 2
- ZCDCYZJXPRHZJC-UHFFFAOYSA-N 1-methyl-2-[[(2-methylphenyl)-phenylmethoxy]-phenylmethyl]benzene Chemical compound CC1=CC=CC=C1C(C=1C=CC=CC=1)OC(C=1C(=CC=CC=1)C)C1=CC=CC=C1 ZCDCYZJXPRHZJC-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- VQUHJCXEMYESBB-UHFFFAOYSA-N dihexadecyl sulfate Chemical compound CCCCCCCCCCCCCCCCOS(=O)(=O)OCCCCCCCCCCCCCCCC VQUHJCXEMYESBB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- MXHODDGKGSGCDI-UHFFFAOYSA-N histapyrrodine Chemical class C=1C=CC=CC=1CN(C=1C=CC=CC=1)CCN1CCCC1 MXHODDGKGSGCDI-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C305/00—Esters of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C305/00—Esters of sulfuric acids
- C07C305/02—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton
- C07C305/04—Esters of sulfuric acids having oxygen atoms of sulfate groups bound to acyclic carbon atoms of a carbon skeleton being acyclic and saturated
- C07C305/06—Hydrogenosulfates
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB54098A DE1103924B (de) | 1959-07-21 | 1959-07-21 | Verfahren zur Herstellung wasserunloeslicher Salze von basischen Antihistaminica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB879901A true GB879901A (en) | 1961-10-11 |
Family
ID=6970487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22820/60A Expired GB879901A (en) | 1959-07-21 | 1960-06-29 | New water-insoluble salts of basic antihistaminics |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE592585A (en, 2012) |
| CH (1) | CH381685A (en, 2012) |
| DE (1) | DE1103924B (en, 2012) |
| FR (1) | FR977M (en, 2012) |
| GB (1) | GB879901A (en, 2012) |
| LU (1) | LU38913A1 (en, 2012) |
-
1959
- 1959-07-21 DE DEB54098A patent/DE1103924B/de active Pending
-
1960
- 1960-06-17 CH CH692360A patent/CH381685A/de unknown
- 1960-06-29 GB GB22820/60A patent/GB879901A/en not_active Expired
- 1960-07-04 LU LU38913D patent/LU38913A1/xx unknown
- 1960-07-04 BE BE592585A patent/BE592585A/fr unknown
- 1960-10-11 FR FR840818A patent/FR977M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE1103924B (de) | 1961-04-06 |
| BE592585A (fr) | 1960-10-31 |
| LU38913A1 (en, 2012) | 1960-09-05 |
| FR977M (en, 2012) | 1961-12-04 |
| CH381685A (de) | 1964-09-15 |
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