GB870395A - Acyl derivatives of 6-aminopenicillanic acid - Google Patents
Acyl derivatives of 6-aminopenicillanic acidInfo
- Publication number
- GB870395A GB870395A GB2460757A GB2460757A GB870395A GB 870395 A GB870395 A GB 870395A GB 2460757 A GB2460757 A GB 2460757A GB 2460757 A GB2460757 A GB 2460757A GB 870395 A GB870395 A GB 870395A
- Authority
- GB
- United Kingdom
- Prior art keywords
- penicillin
- chloride
- acid
- penicillins
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 title abstract 3
- 125000002252 acyl group Chemical group 0.000 title 1
- 229930182555 Penicillin Natural products 0.000 abstract 11
- 229940049954 penicillin Drugs 0.000 abstract 6
- 150000002960 penicillins Chemical class 0.000 abstract 5
- -1 betanaphthoxymethyl penicillin Chemical compound 0.000 abstract 4
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 3
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 150000008065 acid anhydrides Chemical class 0.000 abstract 2
- 238000000855 fermentation Methods 0.000 abstract 2
- 230000004151 fermentation Effects 0.000 abstract 2
- 239000000376 reactant Substances 0.000 abstract 2
- PKUPAJQAJXVUEK-UHFFFAOYSA-N 2-phenoxyacetyl chloride Chemical compound ClC(=O)COC1=CC=CC=C1 PKUPAJQAJXVUEK-UHFFFAOYSA-N 0.000 abstract 1
- VMZCDNSFRSVYKQ-UHFFFAOYSA-N 2-phenylacetyl chloride Chemical compound ClC(=O)CC1=CC=CC=C1 VMZCDNSFRSVYKQ-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000012346 acetyl chloride Substances 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- AOGYCOYQMAVAFD-UHFFFAOYSA-N chlorocarbonic acid Chemical compound OC(Cl)=O AOGYCOYQMAVAFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2460757A GB870395A (en) | 1957-08-02 | 1957-08-02 | Acyl derivatives of 6-aminopenicillanic acid |
| CH6246358A CH382373A (de) | 1957-08-02 | 1958-07-31 | Verfahren zur Herstellung antibiotisch wirksamer Verbindungen |
| CH538364A CH392511A (de) | 1957-08-02 | 1958-07-31 | Verfahren zur Herstellung von N-Acylverbindungen der 6-Amino-penicillansäure |
| DK283858A DK129937B (da) | 1957-08-02 | 1958-08-02 | 6-Aminopenicillansyre og salte deraf til anvendelse ved syntetisk fremstilling af 6-aminopenicillansyrederivater og fremgangsmåde til fremstilling deraf. |
| DK342360A DK110244C (da) | 1957-08-02 | 1958-08-02 | Fremgangsmåde til fremstillin af 6-amino-penicillansyrederivater eller salte deraf. |
| CY32165A CY321A (en) | 1957-08-02 | 1965-10-25 | Acyl derivatives of 6-aminopenicillanic acid |
| MY6500176A MY6500176A (en) | 1957-08-02 | 1965-12-30 | Acyl derivatives of 6-aminopenicillanic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2460757A GB870395A (en) | 1957-08-02 | 1957-08-02 | Acyl derivatives of 6-aminopenicillanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB870395A true GB870395A (en) | 1961-06-14 |
Family
ID=10214322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2460757A Expired GB870395A (en) | 1957-08-02 | 1957-08-02 | Acyl derivatives of 6-aminopenicillanic acid |
Country Status (5)
| Country | Link |
|---|---|
| CH (2) | CH382373A (enrdf_load_stackoverflow) |
| CY (1) | CY321A (enrdf_load_stackoverflow) |
| DK (2) | DK129937B (enrdf_load_stackoverflow) |
| GB (1) | GB870395A (enrdf_load_stackoverflow) |
| MY (1) | MY6500176A (enrdf_load_stackoverflow) |
-
1957
- 1957-08-02 GB GB2460757A patent/GB870395A/en not_active Expired
-
1958
- 1958-07-31 CH CH6246358A patent/CH382373A/de unknown
- 1958-07-31 CH CH538364A patent/CH392511A/de unknown
- 1958-08-02 DK DK283858A patent/DK129937B/da unknown
- 1958-08-02 DK DK342360A patent/DK110244C/da active
-
1965
- 1965-10-25 CY CY32165A patent/CY321A/xx unknown
- 1965-12-30 MY MY6500176A patent/MY6500176A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY321A (en) | 1965-10-25 |
| CH392511A (de) | 1965-05-31 |
| DK129937C (enrdf_load_stackoverflow) | 1975-05-12 |
| DK110244C (da) | 1974-05-20 |
| MY6500176A (en) | 1965-12-31 |
| CH382373A (de) | 1964-09-30 |
| DK129937B (da) | 1974-12-02 |
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