GB8606762D0 - Therapeutic agents - Google Patents
Therapeutic agentsInfo
- Publication number
 - GB8606762D0 GB8606762D0 GB868606762A GB8606762A GB8606762D0 GB 8606762 D0 GB8606762 D0 GB 8606762D0 GB 868606762 A GB868606762 A GB 868606762A GB 8606762 A GB8606762 A GB 8606762A GB 8606762 D0 GB8606762 D0 GB 8606762D0
 - Authority
 - GB
 - United Kingdom
 - Prior art keywords
 - compaction
 - ibuprofen
 - composition
 - therapeutic agents
 - crystalline ibuprofen
 - Prior art date
 - Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
 - Pending
 
Links
- 239000003814 drug Substances 0.000 title 1
 - 229940124597 therapeutic agent Drugs 0.000 title 1
 - HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 abstract 4
 - 229960001680 ibuprofen Drugs 0.000 abstract 4
 - 238000005056 compaction Methods 0.000 abstract 3
 - 239000000203 mixture Substances 0.000 abstract 2
 - 239000008194 pharmaceutical composition Substances 0.000 abstract 2
 - 239000013078 crystal Substances 0.000 abstract 1
 - 238000004090 dissolution Methods 0.000 abstract 1
 - 238000001125 extrusion Methods 0.000 abstract 1
 - 239000008187 granular material Substances 0.000 abstract 1
 - 238000005469 granulation Methods 0.000 abstract 1
 - 230000003179 granulation Effects 0.000 abstract 1
 - 238000000034 method Methods 0.000 abstract 1
 - 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
 - 239000007787 solid Substances 0.000 abstract 1
 
Classifications
- 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
 - A61K9/00—Medicinal preparations characterised by special physical form
 - A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
 - A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
 - A61K31/00—Medicinal preparations containing organic active ingredients
 - A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
 - A61K31/19—Carboxylic acids, e.g. valproic acid
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
 - A61K9/00—Medicinal preparations characterised by special physical form
 - A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
 - A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
 - A61K9/1682—Processes
 - A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
 - A61P25/00—Drugs for disorders of the nervous system
 - A61P25/04—Centrally acting analgesics, e.g. opioids
 
 - 
        
- A—HUMAN NECESSITIES
 - A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
 - A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
 - A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
 
 
Landscapes
- Health & Medical Sciences (AREA)
 - Engineering & Computer Science (AREA)
 - Bioinformatics & Cheminformatics (AREA)
 - Chemical & Material Sciences (AREA)
 - Medicinal Chemistry (AREA)
 - Pharmacology & Pharmacy (AREA)
 - Life Sciences & Earth Sciences (AREA)
 - Animal Behavior & Ethology (AREA)
 - General Health & Medical Sciences (AREA)
 - Public Health (AREA)
 - Veterinary Medicine (AREA)
 - Epidemiology (AREA)
 - Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
 - Chemical Kinetics & Catalysis (AREA)
 - General Chemical & Material Sciences (AREA)
 - Pain & Pain Management (AREA)
 - Organic Chemistry (AREA)
 - Rheumatology (AREA)
 - Biomedical Technology (AREA)
 - Neurology (AREA)
 - Neurosurgery (AREA)
 - Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
 - Medicinal Preparation (AREA)
 - Steroid Compounds (AREA)
 - Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
 - Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
 - Medical Preparation Storing Or Oral Administration Devices (AREA)
 - Medicines Containing Material From Animals Or Micro-Organisms (AREA)
 - Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
 - Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
 - Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
 - Polyurethanes Or Polyureas (AREA)
 
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| GB868606762A GB8606762D0 (en) | 1986-03-19 | 1986-03-19 | Therapeutic agents | 
| DE8787301825T DE3771544D1 (de) | 1986-03-19 | 1987-03-03 | Ibupropfen-kristallaggregate enthaltendes arzneimittel. | 
| AT87301825T ATE65393T1 (de) | 1986-03-19 | 1987-03-03 | Ibupropfen-kristallaggregate enthaltendes arzneimittel. | 
| GB8704987A GB2187952B (en) | 1986-03-19 | 1987-03-03 | Therapeutic agents | 
| EP87301825A EP0241126B1 (en) | 1986-03-19 | 1987-03-03 | Pharmaceutical composition comprising aggregates of crystals of ibuprofen | 
| NZ219560A NZ219560A (en) | 1986-03-19 | 1987-03-10 | Solid pharmaceutical compositions containing ibuprofen | 
| IN174/MAS/87A IN163939B (en:Method) | 1986-03-19 | 1987-03-12 | |
| IL81884A IL81884A0 (en) | 1986-03-19 | 1987-03-13 | Ibuprofen compositions | 
| FI871112A FI871112A7 (fi) | 1986-03-19 | 1987-03-13 | Terapeuttisia aineita. | 
| ZA871836A ZA871836B (en) | 1986-03-19 | 1987-03-13 | Therapeutic agents | 
| DK136487A DK136487A (da) | 1986-03-19 | 1987-03-17 | Farmaceutisk praeparat indeholdende ibuprofen og fremgangsmaade til fremstilling deraf | 
| DD87300859A DD263232A5 (de) | 1986-03-19 | 1987-03-17 | Therapeutische mittel | 
| KR870002431A KR870008582A (ko) | 1986-03-19 | 1987-03-18 | 치료제의 제조방법 | 
| CS871827A CS182787A2 (en) | 1986-03-19 | 1987-03-18 | Method of ibuprophen granules preparation | 
| JP62063658A JPS62230723A (ja) | 1986-03-19 | 1987-03-18 | イブプロフエン含有医薬組成物 | 
| NO871120A NO871120L (no) | 1986-03-19 | 1987-03-18 | Fremgangsmaate for fremstilling av et fast farmasoeytisk preparat. | 
| HU871184A HU195422B (en) | 1986-03-19 | 1987-03-18 | Process for producing ibuprofene granules | 
| PL1987264695A PL264695A1 (en) | 1986-03-19 | 1987-03-18 | Method for manufacturing a pharmaceutical composition | 
| AU70177/87A AU7017787A (en) | 1986-03-19 | 1987-03-19 | Solid pharmaceutical composition of granules of crystalline aggregates of ibuprofen | 
| PT84526A PT84526B (pt) | 1986-03-19 | 1987-03-19 | Processo para a preparacao de uma composicao solida compreendendo granulos consistindo essencialmente de um agregado de cristais de ibuprofeno | 
| YU00470/87A YU47087A (en) | 1986-03-19 | 1987-03-19 | Process for obtaining granulous ibuprophene | 
| CN198787101974A CN87101974A (zh) | 1986-03-19 | 1987-03-19 | 治疗剂 | 
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| GB868606762A GB8606762D0 (en) | 1986-03-19 | 1986-03-19 | Therapeutic agents | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| GB8606762D0 true GB8606762D0 (en) | 1986-04-23 | 
Family
ID=10594868
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| GB868606762A Pending GB8606762D0 (en) | 1986-03-19 | 1986-03-19 | Therapeutic agents | 
| GB8704987A Revoked GB2187952B (en) | 1986-03-19 | 1987-03-03 | Therapeutic agents | 
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| GB8704987A Revoked GB2187952B (en) | 1986-03-19 | 1987-03-03 | Therapeutic agents | 
Country Status (21)
| Country | Link | 
|---|---|
| EP (1) | EP0241126B1 (en:Method) | 
| JP (1) | JPS62230723A (en:Method) | 
| KR (1) | KR870008582A (en:Method) | 
| CN (1) | CN87101974A (en:Method) | 
| AT (1) | ATE65393T1 (en:Method) | 
| AU (1) | AU7017787A (en:Method) | 
| CS (1) | CS182787A2 (en:Method) | 
| DD (1) | DD263232A5 (en:Method) | 
| DE (1) | DE3771544D1 (en:Method) | 
| DK (1) | DK136487A (en:Method) | 
| FI (1) | FI871112A7 (en:Method) | 
| GB (2) | GB8606762D0 (en:Method) | 
| HU (1) | HU195422B (en:Method) | 
| IL (1) | IL81884A0 (en:Method) | 
| IN (1) | IN163939B (en:Method) | 
| NO (1) | NO871120L (en:Method) | 
| NZ (1) | NZ219560A (en:Method) | 
| PL (1) | PL264695A1 (en:Method) | 
| PT (1) | PT84526B (en:Method) | 
| YU (1) | YU47087A (en:Method) | 
| ZA (1) | ZA871836B (en:Method) | 
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| DE3833448A1 (de) * | 1988-10-01 | 1990-04-12 | Hoechst Ag | Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung | 
| NZ234587A (en) * | 1989-08-04 | 1991-11-26 | Mcneil Ppc Inc | A chewable pharmaceutical tablet of compressed coated granules | 
| CA2063141C (en) * | 1989-08-04 | 1997-03-04 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets | 
| US5191114A (en) * | 1991-10-09 | 1993-03-02 | Sage Pharmaceuticals, Inc. | Process for enhancing the flow characteristics of ibuprofen | 
| US5605930A (en) * | 1991-10-21 | 1997-02-25 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for treating and preventing pathologies including cancer | 
| AU1193092A (en) * | 1992-01-10 | 1993-08-03 | Obschestvo S Ogranichennoi Otvetstvennostju Meditsinsky Nauchno-Proizvodstvenny Komplex Biotiki | Granulated pharmaceutical composition and method of obtaining it | 
| EG20677A (en) * | 1993-10-01 | 1999-11-30 | Astra Ag | Method and an apparatus for micronizing the particle size | 
| IS1736B (is) | 1993-10-01 | 1999-12-30 | Astra Ab | Aðferð og tæki sem stuðla að aukinni samloðun agna | 
| TWI225402B (en) | 1996-03-13 | 2004-12-21 | Biochemie Gmbh | Auxiliary-free agglomerates | 
| FR2804603B1 (fr) * | 2000-02-04 | 2004-01-23 | Rhodia Chimie Sa | Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques | 
| DE102005037630A1 (de) | 2005-08-09 | 2007-02-15 | Glatt Gmbh | Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung | 
| ES2821528T3 (es) | 2012-11-14 | 2021-04-26 | Grace W R & Co | Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado | 
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US4476248A (en) * | 1983-02-28 | 1984-10-09 | The Upjohn Company | Crystallization of ibuprofen | 
| JPS60120616A (ja) * | 1983-12-05 | 1985-06-28 | Yaskawa Electric Mfg Co Ltd | プリセット型可逆カウンタ装置 | 
| US4609675A (en) * | 1984-08-17 | 1986-09-02 | The Upjohn Company | Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing | 
- 
        1986
        
- 1986-03-19 GB GB868606762A patent/GB8606762D0/en active Pending
 
 - 
        1987
        
- 1987-03-03 AT AT87301825T patent/ATE65393T1/de active
 - 1987-03-03 EP EP87301825A patent/EP0241126B1/en not_active Expired - Lifetime
 - 1987-03-03 GB GB8704987A patent/GB2187952B/en not_active Revoked
 - 1987-03-03 DE DE8787301825T patent/DE3771544D1/de not_active Expired - Fee Related
 - 1987-03-10 NZ NZ219560A patent/NZ219560A/xx unknown
 - 1987-03-12 IN IN174/MAS/87A patent/IN163939B/en unknown
 - 1987-03-13 IL IL81884A patent/IL81884A0/xx unknown
 - 1987-03-13 ZA ZA871836A patent/ZA871836B/xx unknown
 - 1987-03-13 FI FI871112A patent/FI871112A7/fi not_active IP Right Cessation
 - 1987-03-17 DD DD87300859A patent/DD263232A5/de not_active IP Right Cessation
 - 1987-03-17 DK DK136487A patent/DK136487A/da not_active Application Discontinuation
 - 1987-03-18 NO NO871120A patent/NO871120L/no unknown
 - 1987-03-18 CS CS871827A patent/CS182787A2/cs unknown
 - 1987-03-18 PL PL1987264695A patent/PL264695A1/xx unknown
 - 1987-03-18 HU HU871184A patent/HU195422B/hu not_active IP Right Cessation
 - 1987-03-18 KR KR870002431A patent/KR870008582A/ko not_active Withdrawn
 - 1987-03-18 JP JP62063658A patent/JPS62230723A/ja active Pending
 - 1987-03-19 CN CN198787101974A patent/CN87101974A/zh active Pending
 - 1987-03-19 AU AU70177/87A patent/AU7017787A/en not_active Abandoned
 - 1987-03-19 YU YU00470/87A patent/YU47087A/xx unknown
 - 1987-03-19 PT PT84526A patent/PT84526B/pt not_active IP Right Cessation
 
 
Also Published As
| Publication number | Publication date | 
|---|---|
| PT84526B (pt) | 1989-11-10 | 
| IN163939B (en:Method) | 1988-12-10 | 
| GB2187952B (en) | 1990-05-09 | 
| FI871112L (fi) | 1987-09-20 | 
| GB8704987D0 (en) | 1987-04-08 | 
| NO871120D0 (no) | 1987-03-18 | 
| PL264695A1 (en) | 1988-05-12 | 
| ZA871836B (en) | 1987-09-02 | 
| EP0241126A1 (en) | 1987-10-14 | 
| YU47087A (en) | 1988-04-30 | 
| IL81884A0 (en) | 1987-10-20 | 
| EP0241126B1 (en) | 1991-07-24 | 
| PT84526A (en) | 1987-04-01 | 
| KR870008582A (ko) | 1987-10-19 | 
| DK136487D0 (da) | 1987-03-17 | 
| NZ219560A (en) | 1989-05-29 | 
| HU195422B (en) | 1988-05-30 | 
| AU7017787A (en) | 1987-09-24 | 
| DD263232A5 (de) | 1988-12-28 | 
| FI871112A0 (fi) | 1987-03-13 | 
| GB2187952A (en) | 1987-09-23 | 
| DK136487A (da) | 1987-09-20 | 
| FI871112A7 (fi) | 1987-09-20 | 
| DE3771544D1 (de) | 1991-08-29 | 
| NO871120L (no) | 1987-09-21 | 
| JPS62230723A (ja) | 1987-10-09 | 
| CS182787A2 (en) | 1991-05-14 | 
| HUT42939A (en) | 1987-09-28 | 
| CN87101974A (zh) | 1987-10-21 | 
| ATE65393T1 (de) | 1991-08-15 | 
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