GB851951A - Substituted trifluoromethoxy-and trifluoromethylmercapto-phenothiazines - Google Patents
Substituted trifluoromethoxy-and trifluoromethylmercapto-phenothiazinesInfo
- Publication number
- GB851951A GB851951A GB17725/58A GB1772558A GB851951A GB 851951 A GB851951 A GB 851951A GB 17725/58 A GB17725/58 A GB 17725/58A GB 1772558 A GB1772558 A GB 1772558A GB 851951 A GB851951 A GB 851951A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propyl
- methylpropyl
- piperazinyl
- methyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BBRUFMBREYBVQD-UHFFFAOYSA-N 1-(trifluoromethylsulfanyl)-10H-phenothiazine Chemical class FC(F)(F)SC1=CC=CC=2SC3=CC=CC=C3NC12 BBRUFMBREYBVQD-UHFFFAOYSA-N 0.000 title 1
- -1 dialkylaminoalkyl ester Chemical class 0.000 abstract 10
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006569 (C5-C6) heterocyclic group Chemical group 0.000 abstract 1
- UIVRKRXZHKOCSN-UHFFFAOYSA-N 2-(trifluoromethoxy)-10H-phenothiazine Chemical group FC(OC1=CC=2NC3=CC=CC=C3SC2C=C1)(F)F UIVRKRXZHKOCSN-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 150000002990 phenothiazines Chemical class 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US851951XA | 1957-06-18 | 1957-06-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB851951A true GB851951A (en) | 1960-10-19 |
Family
ID=22190062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17725/58A Expired GB851951A (en) | 1957-06-18 | 1958-06-03 | Substituted trifluoromethoxy-and trifluoromethylmercapto-phenothiazines |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE568701A (en:Method) |
| GB (1) | GB851951A (en:Method) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3394131A (en) * | 1961-04-26 | 1968-07-23 | Squibb & Sons Inc | Acid esters of phenothiazine |
| JP2013537881A (ja) * | 2010-09-07 | 2013-10-07 | イムンゲネテイクス・アーゲー | β−アミロイドパシーまたはα−シヌクレオパシーを治療するための２−（Ｒ２−チオ）−１０−［３−（４−Ｒ１−ピペラジン−１−イル）プロピル］−１０Ｈ−フェノチアジン、およびβ−アミロイドパシーまたはα−シヌクレオパシーの診断または事前診断のための方法 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3133917A (en) * | 1964-05-19 | Substituted trifluoromethoxy- and tri- | ||
| US3194733A (en) * | 1961-04-26 | 1965-07-13 | Olin Mathicson Chemical Corp | Phenothiazine compositions and method of treating mental disorders |
-
0
- BE BE568701D patent/BE568701A/xx unknown
-
1958
- 1958-06-03 GB GB17725/58A patent/GB851951A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3394131A (en) * | 1961-04-26 | 1968-07-23 | Squibb & Sons Inc | Acid esters of phenothiazine |
| JP2013537881A (ja) * | 2010-09-07 | 2013-10-07 | イムンゲネテイクス・アーゲー | β−アミロイドパシーまたはα−シヌクレオパシーを治療するための２−（Ｒ２−チオ）−１０−［３−（４−Ｒ１−ピペラジン−１−イル）プロピル］−１０Ｈ−フェノチアジン、およびβ−アミロイドパシーまたはα−シヌクレオパシーの診断または事前診断のための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE568701A (en:Method) |
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