GB906452A - N-substituted-dibenzo [b.f.] azepines and their preparation - Google Patents
N-substituted-dibenzo [b.f.] azepines and their preparationInfo
- Publication number
- GB906452A GB906452A GB40483/58A GB4048358A GB906452A GB 906452 A GB906452 A GB 906452A GB 40483/58 A GB40483/58 A GB 40483/58A GB 4048358 A GB4048358 A GB 4048358A GB 906452 A GB906452 A GB 906452A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dibenzo
- preparation
- general formula
- compound
- azepines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001538 azepines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- CKDWPUIZGOQOOM-UHFFFAOYSA-N Carbamyl chloride Chemical compound NC(Cl)=O CKDWPUIZGOQOOM-UHFFFAOYSA-N 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 230000002082 anti-convulsion Effects 0.000 abstract 1
- 230000003556 anti-epileptic effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
The invention comprises 5-dibenzo[b.f.]azepine derivatives of the general formula <FORM:0906452/IV (b)/1> (wherein each X represents a hydrogen or halogen atom, and R1 and R2 each represent a hydrogen atom or an alkyl radical, whilst two such alkyl radicals may be linked directly or through an oxygen atom to form a 5- or 6-membered heterocyclic ring), and the preparation thereof by reacting a compound of the general formula <FORM:0906452/IV (b)/2> with a carbamic acid chloride Cl-CO-NR1R2, or with phosgene followed by reaction of the resulting 5-chlorocarbonyl derivative with a compound HNR1R2. The products are useful as anti-convulsive (particularly anti-epileptic) agents. Specification 820,476 is referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH5402357A CH366541A (en) | 1957-12-20 | 1957-12-20 | Process for the preparation of new N-heterocyclic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB906452A true GB906452A (en) | 1962-09-19 |
Family
ID=4519031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB40483/58A Expired GB906452A (en) | 1957-12-20 | 1958-12-16 | N-substituted-dibenzo [b.f.] azepines and their preparation |
Country Status (5)
Country | Link |
---|---|
CH (1) | CH366541A (en) |
CY (1) | CY330A (en) |
GB (1) | GB906452A (en) |
MY (1) | MY6600030A (en) |
NL (1) | NL107186C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0108715A1 (en) * | 1982-10-15 | 1984-05-16 | Ciba-Geigy Ag | Dibenzazepine carboxamides |
-
1957
- 1957-12-20 CH CH5402357A patent/CH366541A/en unknown
-
1958
- 1958-12-16 GB GB40483/58A patent/GB906452A/en not_active Expired
- 1958-12-19 NL NL234420A patent/NL107186C/nl active
-
1965
- 1965-12-08 CY CY33065A patent/CY330A/en unknown
-
1966
- 1966-12-31 MY MY196630A patent/MY6600030A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0108715A1 (en) * | 1982-10-15 | 1984-05-16 | Ciba-Geigy Ag | Dibenzazepine carboxamides |
Also Published As
Publication number | Publication date |
---|---|
MY6600030A (en) | 1966-12-31 |
NL107186C (en) | 1963-08-15 |
CH366541A (en) | 1963-01-15 |
CY330A (en) | 1965-12-08 |
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