GB823265A - Novel oxazolidone compounds and methods for producing the same - Google Patents
Novel oxazolidone compounds and methods for producing the sameInfo
- Publication number
- GB823265A GB823265A GB2865656A GB2865656A GB823265A GB 823265 A GB823265 A GB 823265A GB 2865656 A GB2865656 A GB 2865656A GB 2865656 A GB2865656 A GB 2865656A GB 823265 A GB823265 A GB 823265A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- hydrogen
- alkyl radical
- compounds
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
The invention comprises oxazolid-4-one compounds having in free base form the formula <FORM:0823265/IV (a)/1> or <FORM:0823265/IV (a)/2> wherein R2 represents hydrogen or a lower (C1-5) alkyl radical and R3 and R4 are the same or different and represent hydrogen or lower alkyl radicals), and the preparation thereof by reacting, in the presence of an acid catalyst, a glycollamide R-CH(OH)-CONH2 with an aldehyde or ketone R1=C=O (wherein either R represents hydrogen or a lower alkyl radical and R1 represents hydrogen plus CCl3, or R represents CCl3 and R1 represents two hydrogen atoms, a hydrogen atom plus a lower alkyl radical, or two lower alkyl radicals), and, if desired, when the product is a 2-trichloromethyl-oxazolid-4-one, reacting it with a lower alkylating agent under basic conditions. The products are useful as anti-convulsive agents and, in the case of the 5-trichloromethyl compounds (of which there are two isomers when R3 and R4 are different), as hypnotics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2865656A GB823265A (en) | 1956-09-19 | 1956-09-19 | Novel oxazolidone compounds and methods for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2865656A GB823265A (en) | 1956-09-19 | 1956-09-19 | Novel oxazolidone compounds and methods for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB823265A true GB823265A (en) | 1959-11-11 |
Family
ID=10279045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2865656A Expired GB823265A (en) | 1956-09-19 | 1956-09-19 | Novel oxazolidone compounds and methods for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB823265A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116532109A (en) * | 2023-05-04 | 2023-08-04 | 济南大学 | Preparation method of supported catalyst, obtained product and application |
-
1956
- 1956-09-19 GB GB2865656A patent/GB823265A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116532109A (en) * | 2023-05-04 | 2023-08-04 | 济南大学 | Preparation method of supported catalyst, obtained product and application |
| CN116532109B (en) * | 2023-05-04 | 2024-05-28 | 济南大学 | Preparation method of supported catalyst, obtained product and application |
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