ES316517A1 - Procedure for preparing compounds of 1,1-difenil-2-methyl-3-aminopropanol. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparing compounds of 1,1-difenil-2-methyl-3-aminopropanol. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES316517A1
ES316517A1 ES0316517A ES316517A ES316517A1 ES 316517 A1 ES316517 A1 ES 316517A1 ES 0316517 A ES0316517 A ES 0316517A ES 316517 A ES316517 A ES 316517A ES 316517 A1 ES316517 A1 ES 316517A1
Authority
ES
Spain
Prior art keywords
translation
methyl
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0316517A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES316517A1 publication Critical patent/ES316517A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C07C215/32—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton containing hydroxy groups and carbon atoms of two six-membered aromatic rings bound to the same carbon atom of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Process for preparing 1,1-diphenyl-2-methyl-3-aminopropanol compounds of the formula: ** (See formula) ** wherein X, X ', X' ', Y, Y' and Y '' are each a member selected from the group consisting of hydrogen, lower alkyl containing from one to four carbon atoms, inclusive, lower alkoxy containing from one to four carbon atoms, inclusive, and halogen, characterized in that benzophenone of the formula is reacted: ** (See formula) ** wherein X, X ', X' ', Y, Y' and Y '' are as described above, with propionitrile in the presence of an alkaline condensing agent in an anhydrous solvent system and reducing the product to the corresponding primary amine of the above mentioned formula. (Machine-translation by Google Translate, not legally binding)
ES0316517A 1964-08-26 1965-08-16 Procedure for preparing compounds of 1,1-difenil-2-methyl-3-aminopropanol. (Machine-translation by Google Translate, not legally binding) Expired ES316517A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39230164A 1964-08-26 1964-08-26

Publications (1)

Publication Number Publication Date
ES316517A1 true ES316517A1 (en) 1966-04-01

Family

ID=23550057

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0316517A Expired ES316517A1 (en) 1964-08-26 1965-08-16 Procedure for preparing compounds of 1,1-difenil-2-methyl-3-aminopropanol. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
BE (1) BE668835A (en)
DE (1) DE1518416A1 (en)
ES (1) ES316517A1 (en)
FR (1) FR5932M (en)
GB (1) GB1114122A (en)

Also Published As

Publication number Publication date
DE1518416A1 (en) 1969-08-07
FR5932M (en) 1968-04-08
BE668835A (en) 1966-02-28
GB1114122A (en) 1968-05-15

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