GB822797A - Improvements relating to the manufacturing of dl--a-bromo--ß hydroxy-butyric acid - Google Patents

Improvements relating to the manufacturing of dl--a-bromo--ß hydroxy-butyric acid

Info

Publication number
GB822797A
GB822797A GB10469/58A GB1046958A GB822797A GB 822797 A GB822797 A GB 822797A GB 10469/58 A GB10469/58 A GB 10469/58A GB 1046958 A GB1046958 A GB 1046958A GB 822797 A GB822797 A GB 822797A
Authority
GB
United Kingdom
Prior art keywords
water
bromo
organic solvent
hydroxy
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10469/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Charles E Frosst and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Charles E Frosst and Co filed Critical Charles E Frosst and Co
Publication of GB822797A publication Critical patent/GB822797A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DL-a -bromo-b -hydroxybutyric acid is prepared by bringing together in an aqueous medium crotonic acid and N-bromosuccinimide, whereby at least one (preferably substantially one) molecular proportion of hypobromous acid is generated in situ per molecular proportion of crotonic acid, and adds at the double bond thereof; and isolating the product. Preferably the reaction is effected at room temperature; the reaction medium may be water, a homogeneous mixture of water with an organic solvent such as acetone, or a two-phase mixture of water with an organic solvent such as ether. The product may be extracted by saturating the reaction mixture with sodium chloride and extracting with a water-immiscible organic solvent such as ether.
GB10469/58A 1957-04-23 1958-04-01 Improvements relating to the manufacturing of dl--a-bromo--ß hydroxy-butyric acid Expired GB822797A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA822797X 1957-04-23

Publications (1)

Publication Number Publication Date
GB822797A true GB822797A (en) 1959-10-28

Family

ID=4172593

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10469/58A Expired GB822797A (en) 1957-04-23 1958-04-01 Improvements relating to the manufacturing of dl--a-bromo--ß hydroxy-butyric acid

Country Status (1)

Country Link
GB (1) GB822797A (en)

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