GB802622A - Improvements in the production of n-(2-pyrimidylsulphenyl)-morpholines - Google Patents
Improvements in the production of n-(2-pyrimidylsulphenyl)-morpholinesInfo
- Publication number
- GB802622A GB802622A GB19414/57A GB1941457A GB802622A GB 802622 A GB802622 A GB 802622A GB 19414/57 A GB19414/57 A GB 19414/57A GB 1941457 A GB1941457 A GB 1941457A GB 802622 A GB802622 A GB 802622A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrimidylsulphenyl
- morpholines
- mercapto
- aqueous
- halomorpholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/36—Sulfur-, selenium-, or tellurium-containing compounds
- C08K5/43—Compounds containing sulfur bound to nitrogen
Abstract
N - (2 - pyrimidylsulphenyl) - morpholines are prepared by reacting an alkaline solution of a 2-mercaptopyrimidine with a N-halomorpholine. The alkaline medium is preferably an aqueous or alcoholic solution of alkali or alkaline earth metal hydroxides. Suitable 2-mercaptopyrimidines are, for example, 2-mercapto-4-alkyl-, -4,5-dialkyl-, and -4,5,6-trialkylpyrimidines especially the 2-mercapto-4-methyl and 4,6-dimethyl derivatives, or also the corresponding aryl derivatives. The preferred N-halomorpholines are the N-chloro- and N-bromo-morpholines. The reaction is preferably carried out by gradually introducing an aqueous and/or alcoholic solution of an alkali metal salt of a 2-mercaptopyrimidine into a N-halomorpholine. The products are vulcanization accelerators and also intermediates in the synthesis of pharmaceuticals. In examples, N - (4 - methyl - 2 - pyrimidylsulphenyl) - morpholine is prepared by adding an aqueous or methanolic sodium hydroxide solution of 2-mercapto - 4 - methylpyrimidine to N - chloromorpholine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE802622X | 1957-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB802622A true GB802622A (en) | 1958-10-08 |
Family
ID=6719350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19414/57A Expired GB802622A (en) | 1957-01-19 | 1957-06-20 | Improvements in the production of n-(2-pyrimidylsulphenyl)-morpholines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB802622A (en) |
-
1957
- 1957-06-20 GB GB19414/57A patent/GB802622A/en not_active Expired
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