GB755755A - Improvements in or relating to the preparation of long acting insulin - Google Patents
Improvements in or relating to the preparation of long acting insulinInfo
- Publication number
- GB755755A GB755755A GB717054A GB717054A GB755755A GB 755755 A GB755755 A GB 755755A GB 717054 A GB717054 A GB 717054A GB 717054 A GB717054 A GB 717054A GB 755755 A GB755755 A GB 755755A
- Authority
- GB
- United Kingdom
- Prior art keywords
- insulin
- preparation
- isothiocyanate
- relating
- long acting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
An insulin preparation having a protracted effect comprises the reaction product of insulin e.g. amorphous and crystalline insulin, and an isothiocyanate of aliphatic, aromatic, isocyclic, or heterocyclic compounds e.g. phenyl, ethyl, alkyl or octyl isothiocyanate. The isothiocyanate may be stirred into an aqueous alkaline solution of the insulin e.g. in a phosphate or borate buffer solution, at room temperature, and the required product separated as a solid precipitate or aqueous layer. Reference is made to the production of insulin isocyanate. The insulin may be prepared by the process of U.S.A. Specification 2,595,278.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB717054A GB755755A (en) | 1954-03-11 | 1954-03-11 | Improvements in or relating to the preparation of long acting insulin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB717054A GB755755A (en) | 1954-03-11 | 1954-03-11 | Improvements in or relating to the preparation of long acting insulin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB755755A true GB755755A (en) | 1956-08-29 |
Family
ID=9827957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB717054A Expired GB755755A (en) | 1954-03-11 | 1954-03-11 | Improvements in or relating to the preparation of long acting insulin |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB755755A (en) |
-
1954
- 1954-03-11 GB GB717054A patent/GB755755A/en not_active Expired
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