GB755225A - Improvements in or relating to a pyrimidine compound - Google Patents

Improvements in or relating to a pyrimidine compound

Info

Publication number
GB755225A
GB755225A GB258/54A GB25854A GB755225A GB 755225 A GB755225 A GB 755225A GB 258/54 A GB258/54 A GB 258/54A GB 25854 A GB25854 A GB 25854A GB 755225 A GB755225 A GB 755225A
Authority
GB
United Kingdom
Prior art keywords
relating
pyrimidine compound
pyrimidine
phosphorus oxychloride
phosphorus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB258/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of GB755225A publication Critical patent/GB755225A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises 2,4-dichloropyrido (3,2-d) pyrimidine of the formula <FORM:0755225/IV(a)/1> and the preparation thereof by heating 3-aminopicolinic acid with urea and chlorinating the resulting 2,4-dihydroxypyrido(3,2-d)pyrimidine e.g., with phosphorus oxychloride. One detailed example is given using a mixture of phosphorus oxychloride and phosphorus pentachloride for the chlorination step.
GB258/54A 1953-01-14 1954-01-05 Improvements in or relating to a pyrimidine compound Expired GB755225A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US755225XA 1953-01-14 1953-01-14

Publications (1)

Publication Number Publication Date
GB755225A true GB755225A (en) 1956-08-22

Family

ID=22126322

Family Applications (1)

Application Number Title Priority Date Filing Date
GB258/54A Expired GB755225A (en) 1953-01-14 1954-01-05 Improvements in or relating to a pyrimidine compound

Country Status (1)

Country Link
GB (1) GB755225A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0404355A1 (en) * 1989-05-30 1990-12-27 Smithkline Beecham Intercredit B.V. Pyridopyrimidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0404355A1 (en) * 1989-05-30 1990-12-27 Smithkline Beecham Intercredit B.V. Pyridopyrimidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them

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