GB706177A - Improvements in and relating to the manufacture of p-aminosalicylic acid - Google Patents

Improvements in and relating to the manufacture of p-aminosalicylic acid

Info

Publication number
GB706177A
GB706177A GB15818/50A GB1581850A GB706177A GB 706177 A GB706177 A GB 706177A GB 15818/50 A GB15818/50 A GB 15818/50A GB 1581850 A GB1581850 A GB 1581850A GB 706177 A GB706177 A GB 706177A
Authority
GB
United Kingdom
Prior art keywords
relating
manufacture
aminosalicylic acid
ethylene glycol
per cent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15818/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew Nominee Services Ltd
Original Assignee
Herts Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Herts Pharmaceuticals Ltd filed Critical Herts Pharmaceuticals Ltd
Priority to GB15818/50A priority Critical patent/GB706177A/en
Publication of GB706177A publication Critical patent/GB706177A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/56—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Potassium 2-hydroxy-4-aminobenzoate is obtained by heating m-aminophenol at atmospheric pressure with carbon dioxide and at least 2 mols. of potassium carbonate above 160 DEG C. in the absence of water, but with up to 50 per cent. of ethylene glycol. In an example a temperature of 175 DEG C. and about 10 per cent. of the charge of ethylene glycol was used. Specification 636,347 is referred to.
GB15818/50A 1950-06-24 1950-06-24 Improvements in and relating to the manufacture of p-aminosalicylic acid Expired GB706177A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB15818/50A GB706177A (en) 1950-06-24 1950-06-24 Improvements in and relating to the manufacture of p-aminosalicylic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15818/50A GB706177A (en) 1950-06-24 1950-06-24 Improvements in and relating to the manufacture of p-aminosalicylic acid

Publications (1)

Publication Number Publication Date
GB706177A true GB706177A (en) 1954-03-24

Family

ID=10066065

Family Applications (1)

Application Number Title Priority Date Filing Date
GB15818/50A Expired GB706177A (en) 1950-06-24 1950-06-24 Improvements in and relating to the manufacture of p-aminosalicylic acid

Country Status (1)

Country Link
GB (1) GB706177A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012083753A1 (en) * 2010-12-25 2012-06-28 浙江华海药业股份有限公司 Preparation of 5-aminosalicylic acid by gas phase catalytic carboxylation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012083753A1 (en) * 2010-12-25 2012-06-28 浙江华海药业股份有限公司 Preparation of 5-aminosalicylic acid by gas phase catalytic carboxylation
CN103201255A (en) * 2010-12-25 2013-07-10 浙江华海药业股份有限公司 Preparation of 5-aminosalicylic acid by gas phase catalytic carboxylation
CN103201255B (en) * 2010-12-25 2014-11-19 浙江华海药业股份有限公司 Preparation of 5-aminosalicylic acid by gas phase catalytic carboxylation
US9067867B2 (en) 2010-12-25 2015-06-30 Zhejiang Huahai Pharmaceutical Co., Ltd. Preparation of 5-aminosalicylic acid by gas phase catalytic carboxylation

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