GB694497A - Preparation of 2-sulfanilamidoquinoxaline - Google Patents

Preparation of 2-sulfanilamidoquinoxaline

Info

Publication number
GB694497A
GB694497A GB10623/50A GB1062350A GB694497A GB 694497 A GB694497 A GB 694497A GB 10623/50 A GB10623/50 A GB 10623/50A GB 1062350 A GB1062350 A GB 1062350A GB 694497 A GB694497 A GB 694497A
Authority
GB
United Kingdom
Prior art keywords
sulphanilamide
sulphanilamidoquinoxaline
acidified
cooled
sulfanilamidoquinoxaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB10623/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB694497A publication Critical patent/GB694497A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)

Abstract

2-Sulphanilamidoquinoxaline is prepared by heating a mixture of 2-haloquinoxaline, sulphanilamide and an acid-binding agent, particularly an alkali or alkaline earth carbonate, bicarbonate or hydroxide. The temperature may be between 120 DEG and 180 DEG C. In an example, 2-chloroquinoxaline, sulphanilamide and potassium carbonate are heated together to 160-165 DEG C. for five hours, cooled, diluted with water, acidified to pH9 to separate unchanged sulphanilamide, and then acidified and cooled to 0-5 DEG C. to precipitate the 2-sulphanilamidoquinoxaline.
GB10623/50A 1949-05-20 1950-05-01 Preparation of 2-sulfanilamidoquinoxaline Expired GB694497A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US694497XA 1949-05-20 1949-05-20

Publications (1)

Publication Number Publication Date
GB694497A true GB694497A (en) 1953-07-22

Family

ID=22089044

Family Applications (1)

Application Number Title Priority Date Filing Date
GB10623/50A Expired GB694497A (en) 1949-05-20 1950-05-01 Preparation of 2-sulfanilamidoquinoxaline

Country Status (1)

Country Link
GB (1) GB694497A (en)

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