GB660198A - Alkoxyalkanoates of hydroxylated hormones - Google Patents
Alkoxyalkanoates of hydroxylated hormonesInfo
- Publication number
- GB660198A GB660198A GB24006/48A GB2400648A GB660198A GB 660198 A GB660198 A GB 660198A GB 24006/48 A GB24006/48 A GB 24006/48A GB 2400648 A GB2400648 A GB 2400648A GB 660198 A GB660198 A GB 660198A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propoxy
- ethoxyacetate
- butanoate
- testosterone
- hormones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Esters of hydroxylated hormones of the cyclopentanophenanthrene and stilboestrol series are prepared by reacting the hormone in the presence of a base with an alkoxyalkanoyl halide of the general formula R-O-X-CO-Y where R is an alkyl group containing one to four carbon atoms, X is an alkylene group containing one to three carbon atoms and Y is a halogen, or with an alkoxyalkanoic anhydride having the general formula (R-CO-X-CO)2O in which R and X are as above defined. Hormones mentioned include testosterone, oestradiol, oestrone, stilbestrol, and desoxycorticosterone. Esters mentioned include methoxyacetate, ethoxyacetate, n-propoxyacetate, n-butoxyacetate, 3-(2-propoxy)-propanoate, 4-(n-propoxy)-butanoate, 2-methoxypropanoate, 2-ethoxy-butanoate and the 3-(n-propoxy)-butanoate. The preferred basic agent is pyridine. Examples are given of the preparation of the following compounds: testosterone-4-methoxybutanoate; -3-ethoxypropanoate; -n-butoxyacetate; -n-propoxyacetate; and 3-(2-propoxy)-propanoate; testosterone ethoxyacetate; -methoxyacetate; -3-methoxypropanoate; and stilbestrol bis-(ethoxyacetate).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US660198XA | 1947-09-13 | 1947-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB660198A true GB660198A (en) | 1951-10-31 |
Family
ID=22066746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24006/48A Expired GB660198A (en) | 1947-09-13 | 1948-09-13 | Alkoxyalkanoates of hydroxylated hormones |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB660198A (en) |
-
1948
- 1948-09-13 GB GB24006/48A patent/GB660198A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE7613651L (en) | WAY TO PREPARE PHENYLETIC ACID DERIVATIVES | |
| IT1070709B (en) | LIQUID DETERGENT COMPOSITION | |
| GB660198A (en) | Alkoxyalkanoates of hydroxylated hormones | |
| GB660199A (en) | Acyloxyalkanoates of hydroxylated hormones | |
| GB1087920A (en) | Novel 10ª-methyl-9ª-steroids | |
| GB1092194A (en) | Improvements in or relating to ethers of estradiol and its derivatives | |
| GB660197A (en) | Alkyl-mercaptoalkanoates of hydroxylated hormones | |
| GB1135689A (en) | Novel gonane derivatives, processes for their preparation, and compositions incorporation them | |
| GB986579A (en) | 5-ethylidene dibenzocycloheptadienes and the preparation thereof | |
| GB873262A (en) | Stilboestrol and hexoestrol derivatives | |
| GB726786A (en) | New salicyclic acid derivatives | |
| GB911600A (en) | Derivatvies of 17-epi-oestriol and process for the preparation thereof | |
| GB845442A (en) | Manufacture of steroid compounds | |
| ES230580A1 (en) | A procedure for preparing alcohyl transhexahidrotereftalate and steroid hormone (Machine-translation by Google Translate, not legally binding) | |
| GB1016375A (en) | Steroid esters | |
| GB895400A (en) | Pentacyclic steroids and methods of preparing the same | |
| GB686135A (en) | Improvements in cyclopentanophenanthrene derivatives and process for producing the same | |
| GB826953A (en) | New steroid esters and their preparation | |
| NL174344B (en) | PROCESS FOR PREPARING A MIXTURE OF CATECHOL AND HYDROQUINONE. | |
| ES308051A1 (en) | Procedure for the elaboration of new carboxylic acid esters, basically substituted. (Machine-translation by Google Translate, not legally binding) | |
| GB837948A (en) | Reserpic acid diesters and salts thereof and process for their manufacture | |
| GB689825A (en) | Improvements in or relating to trousers or slacks | |
| GB750941A (en) | Steroids | |
| GB937616A (en) | A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids | |
| ES227559A2 (en) | A procedure for the preparation of phenyl carbamates basic. (Machine-translation by Google Translate, not legally binding) |