GB937616A - A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids - Google Patents

A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids

Info

Publication number
GB937616A
GB937616A GB1072860A GB1072860A GB937616A GB 937616 A GB937616 A GB 937616A GB 1072860 A GB1072860 A GB 1072860A GB 1072860 A GB1072860 A GB 1072860A GB 937616 A GB937616 A GB 937616A
Authority
GB
United Kingdom
Prior art keywords
steroids
halomethyl
manufacture
new
pregnan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1072860A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of GB937616A publication Critical patent/GB937616A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 16a -bromomethyl-and 16a -chloromethyl-5a -pregnan-3b -ol-20-one, 16a -iodomethyl-5a -pregnan-3b -ol-20-one 3-formate, and 16a -iodomethyl-D 5-pregnen-3b -ol-20-one 3-formate, and a process for the preparation of 16a -monohalomethyl-steroids having at ring D the general formula:- <FORM:0937616/IV(a)/1> wherein R represents hydrogen or a hydroxy, acyloxy or alkyl ether radical and X represents a halogen, by treating a steroid having at ring D the general formula <FORM:0937616/IV(a)/2> wherein R has the above significance, with a hydrogen halide. Specification 874,322 is referred to.
GB1072860A 1959-04-23 1960-03-25 A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids Expired GB937616A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DESCH25936A DE1096903B (en) 1959-04-23 1959-04-23 Process for the preparation of 16a-monohalomethyl steroids

Publications (1)

Publication Number Publication Date
GB937616A true GB937616A (en) 1963-09-25

Family

ID=7430298

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1072860A Expired GB937616A (en) 1959-04-23 1960-03-25 A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids

Country Status (3)

Country Link
CH (1) CH380120A (en)
DE (1) DE1096903B (en)
GB (1) GB937616A (en)

Also Published As

Publication number Publication date
CH380120A (en) 1964-07-31
DE1096903B (en) 1961-01-12

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