GB590956A - Improvements in and relating to the production of liver products - Google Patents
Improvements in and relating to the production of liver productsInfo
- Publication number
- GB590956A GB590956A GB1020745A GB1020745A GB590956A GB 590956 A GB590956 A GB 590956A GB 1020745 A GB1020745 A GB 1020745A GB 1020745 A GB1020745 A GB 1020745A GB 590956 A GB590956 A GB 590956A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alumina
- solution
- water
- per cent
- relating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004185 Liver Anatomy 0.000 title 1
- 239000000243 solution Substances 0.000 abstract 4
- PNEYBMLMFCGWSK-UHFFFAOYSA-N AI2O3 Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 abstract 2
- 229940040511 Liver Extract Drugs 0.000 abstract 1
- 239000003463 adsorbent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000010908 decantation Methods 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000003394 haemopoietic Effects 0.000 abstract 1
- 239000004576 sand Substances 0.000 abstract 1
- 239000001187 sodium carbonate Substances 0.000 abstract 1
- 229910000029 sodium carbonate Inorganic materials 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A solution of a liver extract is treated with activated alumina so as to adsorb inactive substances present without adsorbing the haemopoietic principle to any substantial extent, and the alumina is thereafter separated, e.g., by decantation, filtration or centrifugation. Or the solution may perfused through a column of the adsorbent, which may be diluted with an inert granular material such as sand. Aqueous solutions, or water-alcohol solutions containing up to 50 per cent. alcohol, may be employed, at a pH between one and eight. The alumina may be recovered by treatment with say five per cent. sodium carbonate solution, followed by washing with water.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB590956A true GB590956A (en) | 1947-08-01 |
Family
ID=1697077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1020745A Expired GB590956A (en) | 1945-04-23 | Improvements in and relating to the production of liver products |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB590956A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2573702A (en) * | 1948-04-09 | 1951-11-06 | Merck & Co Inc | Alumina chromatographic purification of liver extracts |
| US2582589A (en) * | 1949-05-13 | 1952-01-15 | Abbott Lab | Vitamin b12 purification process |
| US2609325A (en) * | 1948-04-03 | 1952-09-02 | Merck & Co Inc | Recovery of vitamin b12 from liver |
| US2653900A (en) * | 1951-06-07 | 1953-09-29 | Merck & Co Inc | Vitamin b12 purification process |
| US2668137A (en) * | 1949-12-13 | 1954-02-02 | Merck & Co Inc | Vitamin b12 elution from charcoal |
| US2677644A (en) * | 1951-10-25 | 1954-05-04 | American Cyanamid Co | Purification of vitamin b12 solutions |
| US2686750A (en) * | 1950-08-25 | 1954-08-17 | Abbott Lab | Vitamin b12 purification process |
-
1945
- 1945-04-23 GB GB1020745A patent/GB590956A/en not_active Expired
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2609325A (en) * | 1948-04-03 | 1952-09-02 | Merck & Co Inc | Recovery of vitamin b12 from liver |
| US2573702A (en) * | 1948-04-09 | 1951-11-06 | Merck & Co Inc | Alumina chromatographic purification of liver extracts |
| US2582589A (en) * | 1949-05-13 | 1952-01-15 | Abbott Lab | Vitamin b12 purification process |
| US2668137A (en) * | 1949-12-13 | 1954-02-02 | Merck & Co Inc | Vitamin b12 elution from charcoal |
| US2686750A (en) * | 1950-08-25 | 1954-08-17 | Abbott Lab | Vitamin b12 purification process |
| US2653900A (en) * | 1951-06-07 | 1953-09-29 | Merck & Co Inc | Vitamin b12 purification process |
| US2677644A (en) * | 1951-10-25 | 1954-05-04 | American Cyanamid Co | Purification of vitamin b12 solutions |
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