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Expired
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GB926/42A
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of GB553190ApublicationCriticalpatent/GB553190A/en
C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
C07C51/41—Preparation of salts of carboxylic acids
C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
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Organic Chemistry
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Engineering & Computer Science
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Oil, Petroleum & Natural Gas
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
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Abstract
553,190. Abietic acid derivatives. HOFFMANN-LA-ROCHE & CO. AKT.-GES., F. Jan. 22, 1942, Nos. 926 and 927. Convention dates, March 26, 1941, and April 3, 1941. [Class 2 (iii)] Derivatives of abietic acid having therapeutic properties are made by treating one molecule of halogen-trihydroxy - abietic acid with 1¢ molecules of alkali, or tetrahydroxy-abietic acid with half the quantity of alkali required for neutralisation, or 2 molecules of tetrahydroxyabietic acid alkali salt with one molecule of acid. A complex compound is obtained containing one free carboxylic acid group and one alkali carboxylate group. Bromo-trihydroxyabietic acid, which is prepared in the same way as chloro-trihydroxy abietic acid but using HBe instead of HCl, may be used as starting material. Both the sodium and potassium compounds are prepared using the corresponding alcoholic alkali hydroxide.
GB926/42A1941-03-261942-01-22Process for the manufacture of therapeutically valuable derivatives of abietic acid
ExpiredGB553190A
(en)
Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -noroximorphone new. (Machine-translation by Google Translate, not legally binding)