GB553190A - Process for the manufacture of therapeutically valuable derivatives of abietic acid - Google Patents

Process for the manufacture of therapeutically valuable derivatives of abietic acid

Info

Publication number
GB553190A
GB553190A GB926/42A GB92642A GB553190A GB 553190 A GB553190 A GB 553190A GB 926/42 A GB926/42 A GB 926/42A GB 92642 A GB92642 A GB 92642A GB 553190 A GB553190 A GB 553190A
Authority
GB
United Kingdom
Prior art keywords
acid
abietic acid
alkali
derivatives
abietic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB926/42A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB553190A publication Critical patent/GB553190A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41Preparation of salts of carboxylic acids
    • C07C51/412Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

553,190. Abietic acid derivatives. HOFFMANN-LA-ROCHE & CO. AKT.-GES., F. Jan. 22, 1942, Nos. 926 and 927. Convention dates, March 26, 1941, and April 3, 1941. [Class 2 (iii)] Derivatives of abietic acid having therapeutic properties are made by treating one molecule of halogen-trihydroxy - abietic acid with 1¢ molecules of alkali, or tetrahydroxy-abietic acid with half the quantity of alkali required for neutralisation, or 2 molecules of tetrahydroxyabietic acid alkali salt with one molecule of acid. A complex compound is obtained containing one free carboxylic acid group and one alkali carboxylate group. Bromo-trihydroxyabietic acid, which is prepared in the same way as chloro-trihydroxy abietic acid but using HBe instead of HCl, may be used as starting material. Both the sodium and potassium compounds are prepared using the corresponding alcoholic alkali hydroxide.
GB926/42A 1941-03-26 1942-01-22 Process for the manufacture of therapeutically valuable derivatives of abietic acid Expired GB553190A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH553190X 1941-03-26

Publications (1)

Publication Number Publication Date
GB553190A true GB553190A (en) 1943-05-11

Family

ID=4519794

Family Applications (1)

Application Number Title Priority Date Filing Date
GB926/42A Expired GB553190A (en) 1941-03-26 1942-01-22 Process for the manufacture of therapeutically valuable derivatives of abietic acid

Country Status (1)

Country Link
GB (1) GB553190A (en)

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