GB703961A - Improvements in derivatives of stilbazoline - Google Patents
Improvements in derivatives of stilbazolineInfo
- Publication number
- GB703961A GB703961A GB5362/52A GB536252A GB703961A GB 703961 A GB703961 A GB 703961A GB 5362/52 A GB5362/52 A GB 5362/52A GB 536252 A GB536252 A GB 536252A GB 703961 A GB703961 A GB 703961A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- iodide
- alkyl
- conversion
- mol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
The invention comprises bis-quaternary stilbazolinium salts of the formula <FORM:0703961/IV(b)/1> where R and R1 are alkyl of 1-4 carbon atoms, one being methyl, S denotes saturation of the ring and X is the anion of an acid. These are made from N-alkyl-41-dimethylamino-g -stil - bazoline hydriodides by (1) conversion to free base and treatment with 2 mols. of methyl iodide to give the product (R1 = methyl); or (2) addition of one mol. of R1, conversion to free base and treatment with one mol. of methyl iodide. Alternatively N-alkyl-41-methylethylamino-stilbazoline hydriodide may be used as starting material; this is obtained from an alkyl-g -picolinium iodide and p-methylethylaminobenzaldehyde followed by catalytic hydrogenation. The above processes yield products where X is iodide; other salts may be obtained by using a different quaternating agent (e.g. a bromide or sulphate) or by subsequent conversion, e.g. into chlorides and nitrates. Examples show the production of compounds (1) R = R1 = methyl, X = iodide, converted into chloride, (2) R = ethyl, R1 = methyl, X = iodide, (3) R = methyl, R1 = ethyl, X = iodide. R or R1 may also be n-propyl or n-butyl.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US703961XA | 1951-03-29 | 1951-03-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB703961A true GB703961A (en) | 1954-02-10 |
Family
ID=22095042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB5362/52A Expired GB703961A (en) | 1951-03-29 | 1952-02-29 | Improvements in derivatives of stilbazoline |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB703961A (en) |
-
1952
- 1952-02-29 GB GB5362/52A patent/GB703961A/en not_active Expired
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