GB513818A - Improvements in and relating to the manufacture of compounds of p-tolylmethylcarbinol - Google Patents
Improvements in and relating to the manufacture of compounds of p-tolylmethylcarbinolInfo
- Publication number
- GB513818A GB513818A GB23865/38A GB2386538A GB513818A GB 513818 A GB513818 A GB 513818A GB 23865/38 A GB23865/38 A GB 23865/38A GB 2386538 A GB2386538 A GB 2386538A GB 513818 A GB513818 A GB 513818A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salts
- ester
- acids
- tolymethylcarbinol
- converted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
513,818. Tolymethylcarbinol derivatives. CHEMISCH-PHARMAZEUTISCHE AKT.- GES. BAD HOMBURG, and KOHLSTAEDT, E. Aug. 12, 1938, No. 23865. [Class 2 (iii)] Water-soluble compounds of therapeutic use are prepared by partially esterifying a dicarboxylic acid with p-tolymethylcarbinol and converting the ester-acid into a salt with an appropriate organic or inorganic base. The process may be effected by reacting equinolecular proportions of the carbinol and a dicarboxylic acid anhydride in the presence of an atomic proportion of an alkali metal; the ester-acids may then be liberated by addition of a mineral acid and converted into their water-soluble salts, e.g. alkali, alkaline earth metal and ammonium salts or salts with diethylamine or ethylene diamine. Examples are given in which the anhydrides of camphoric, phthalic, succinic and maleic acids are treated with sodium p-tolymethylcarbinolate in benzene solution and the resulting ester-acids converted into salts as above.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB23865/38A GB513818A (en) | 1938-08-12 | 1938-08-12 | Improvements in and relating to the manufacture of compounds of p-tolylmethylcarbinol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB23865/38A GB513818A (en) | 1938-08-12 | 1938-08-12 | Improvements in and relating to the manufacture of compounds of p-tolylmethylcarbinol |
Publications (1)
Publication Number | Publication Date |
---|---|
GB513818A true GB513818A (en) | 1939-10-23 |
Family
ID=10202576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB23865/38A Expired GB513818A (en) | 1938-08-12 | 1938-08-12 | Improvements in and relating to the manufacture of compounds of p-tolylmethylcarbinol |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB513818A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3061634A (en) * | 1959-02-17 | 1962-10-30 | Francesco Angelini | Halo and phenyl substituted phenyl lower alkyl carbinol mono esters of succinic, glutaric, and maleic acids |
-
1938
- 1938-08-12 GB GB23865/38A patent/GB513818A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3061634A (en) * | 1959-02-17 | 1962-10-30 | Francesco Angelini | Halo and phenyl substituted phenyl lower alkyl carbinol mono esters of succinic, glutaric, and maleic acids |
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