GB879014A - Water-soluble derivatives of estriol - Google Patents

Water-soluble derivatives of estriol

Info

Publication number
GB879014A
GB879014A GB18667/60A GB1866760A GB879014A GB 879014 A GB879014 A GB 879014A GB 18667/60 A GB18667/60 A GB 18667/60A GB 1866760 A GB1866760 A GB 1866760A GB 879014 A GB879014 A GB 879014A
Authority
GB
United Kingdom
Prior art keywords
estriol
esters
salts
hemiesters
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18667/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Laboratories Ltd
Original Assignee
Organon Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Laboratories Ltd filed Critical Organon Laboratories Ltd
Publication of GB879014A publication Critical patent/GB879014A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 16 : 17-di-hemiesters of estriol with dicarboxylic acids and water soluble salts thereof, and their preparation by reacting estriol with a dicarboxylic acid or a functional derivative thereof and converting the thus obtained 16 : 17-di-hemiesters into salts thereof if desired. Suitable acids are oxalic, malonic, succinic, glutaric, pimelic, fumaric, maleic, malic, tartaric, aspartic, glutamic and phthalic acids, preferably used as anhydrides or halides in the esterification process, and the esters are preferably converted into the alkali metal, ammonium or substituted ammonium salts. Examples are given, the required di-esters being separated from concomitantly formed mono-esters by, for example, fractional crystallization.
GB18667/60A 1959-05-29 1960-05-26 Water-soluble derivatives of estriol Expired GB879014A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL879014X 1959-05-29

Publications (1)

Publication Number Publication Date
GB879014A true GB879014A (en) 1961-10-04

Family

ID=19851508

Family Applications (1)

Application Number Title Priority Date Filing Date
GB18667/60A Expired GB879014A (en) 1959-05-29 1960-05-26 Water-soluble derivatives of estriol

Country Status (1)

Country Link
GB (1) GB879014A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163596A1 (en) * 1984-05-16 1985-12-04 Schering Aktiengesellschaft Estriol esters
EP0196268A2 (en) * 1985-03-21 1986-10-01 Schering Aktiengesellschaft Estriol esters
FR2806725A1 (en) * 2000-03-27 2001-09-28 Oreal DEHYDROEPIANDROSTERONE DERIVATIVES, PROCESS FOR PREPARING THEM AND USES THEREOF, ESPECIALLY COSMETIC

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163596A1 (en) * 1984-05-16 1985-12-04 Schering Aktiengesellschaft Estriol esters
AU571090B2 (en) * 1984-05-16 1988-03-31 Schering Aktiengesellschaft 3, 17beta-estriol diesters
EP0196268A2 (en) * 1985-03-21 1986-10-01 Schering Aktiengesellschaft Estriol esters
EP0196268A3 (en) * 1985-03-21 1987-01-14 Schering Aktiengesellschaft Berlin Und Bergkamen Estriol esters
FR2806725A1 (en) * 2000-03-27 2001-09-28 Oreal DEHYDROEPIANDROSTERONE DERIVATIVES, PROCESS FOR PREPARING THEM AND USES THEREOF, ESPECIALLY COSMETIC
WO2001072767A1 (en) * 2000-03-27 2001-10-04 L'oreal Dehydroepiandrosterone derivatives, preparation method and uses thereof, in particular for cosmetics

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