GB474614A - Method of producing therapeutically and disinfectantly active substances - Google Patents

Method of producing therapeutically and disinfectantly active substances

Info

Publication number
GB474614A
GB474614A GB12517/36A GB1251736A GB474614A GB 474614 A GB474614 A GB 474614A GB 12517/36 A GB12517/36 A GB 12517/36A GB 1251736 A GB1251736 A GB 1251736A GB 474614 A GB474614 A GB 474614A
Authority
GB
United Kingdom
Prior art keywords
solution
silver
chlorauric acid
gold
alkaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12517/36A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SYNGALA FABRIK fur CHEMISCH S
Original Assignee
SYNGALA FABRIK fur CHEMISCH S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SYNGALA FABRIK fur CHEMISCH S filed Critical SYNGALA FABRIK fur CHEMISCH S
Publication of GB474614A publication Critical patent/GB474614A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/23Solid substances, e.g. granules, powders, blocks, tablets
    • A61L2/238Metals or alloys, e.g. oligodynamic metals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Substances containing gold and silver having therapeutic, disinfectant and sterilizing properties are produced by reacting compounds yielding gold and silver ions, in aqueous or other suitable liquid medium, in the presence of alkaline substances with compounds of multivalent metals, a compound of a metal in a lower valency, present as a cation, being employed. Suitable metal compounds are manganous, cobaltous, nickelous, ferrous and cerous salts. The silver salt of chlorauric acid may be used as a compound supplying both silver and gold ions. The alkaline substance may consist of alkalies, alkali carbonates, organic bases, or the oxides, hydroxides or alkaline salts of the multivalent metallic compound used in the reaction. The product comprises finely divided metallic gold and silver and the higher oxide or hydroxide of the multivalent metal used. The reaction may be carried out in the presence of protective colloids, e.g. albuminous bodies, vegetable mucilages, lecithin, whereby colloidal solutions suitable for the treatment of various diseases are obtained. In an example, a gelatin solution is admixed with a solution of silver and manganese nitrates, and a solution of chlorauric acid is then added with stirring. The resultant colloidal solution of the silver salt of chlorauric acid is rendered alkaline with caustic soda solution. The solution is then dialyzed for several days in parchment containers to remove electrolytes. In another example, chlorauric acid solution is added to a solution of manganese and silver nitrates. The silver salt of chlorauric acid precipitates. Excess caustic soda solution is then added and the precipitate filtered, washed and dried. The Specification as open to inspection under Sect. 91 comprises also the precipitation of gold solutions only. This subject-matter does not appear in the Specification as accepted.ALSO:Substances containing gold and silver having therapeutic, disinfectant and sterilizing properties are produced by reacting compounds yielding gold and silver ions, in aqueous or other suitable liquid medium, in the presence of alkaline substances with compounds of multivalent metals, a compound of a metal in a lower valency, present as a cation, being employed. Suitable metal compounds are manganous, cobaltous, nickelous, ferrous and cerous salts. The silver salt of chlorauric acid may be used as a compound supplying both silver and gold ions. The alkaline substance may consist of alkalies, alkali carbonates organic bases, or the oxides, hydroxides or alkaline salts of the multivalent metallic compound used in the reaction. The product comprises finely divided metallic gold and silver, and the higher oxide or hydroxide of the multivalent metal used. The precipitated subsubstance may be deposited directly on carrier material, e.g. surgical dressings, textile fibres, cotton, fabrics, animal charcoal, silica gels, bole and other pulverulent materials. The carrier material may supply the hydroxyl ions, for which purpose it may be of itself alkaline, e.g. alkaline earth carbonates, magnesium or zinc oxide, or it may be pretreated with alkaline substances. The reaction may be carried out in the presence of protective colloids, e.g. albuminous bodies, vegetable mucilages, lecithin, whereby colloidal solutions suitable for the treatment of various diseases are obtained. In an example, a gelatin solution is admixed with a solution of silver and manganese nitrates, and a solution of chlorauric acid is then added with stirring. The resultant colloidal solution of the silver salt of chlorauric acid is rendered alkaline with caustic soda solution. The solution is then dialyzed for several days in parchment containers to remove electrolytes. In other examples: (1) chlorauric acid solution is added to a solution of manganese and silver nitrates. The silver salt of chlorauric acid precipitates. Excess caustic soda solution is then added, and the precipitate filtered, washed and dried; (2) gauze is dipped in a solution of chlorauric acid and manganese nitrate, squeezed out, immersed in a solution of silver and manganese nitrates, expressed, introduced into caustic soda solution, washed and dried. The Specification as open to inspection under Sect. 91 comprises also the precipitation of gold solutions only, and the impregnation of the carrier materials with the precipitate. The gold preparations are stated to activate other oligodynamically active substances, for example, argentiferous substances. In examples: (1) a solution of chlorauric acid and manganese nitrate is admixed with caustic soda solution; a precipitate 2Au.3MnO2 results; (2) a solution of chlorauric acid and cerous nitrate is admixed with caustic potash solution; a precipitate Au.3CeO results; (3) a suspension of precipitated calcium carbonate in a solution of gold chloride and manganese nitrate is boiled; (4) gauze is dipped into a solution of chlorauric acid and manganese nitrate, expressed, and introduced into caustic soda solution; (5) gauze is dipped into a solution of chlorauric acid and manganese nitrate, expressed, introduced into caustic soda solution, washed, immersed in a solution of manganese nitrate and silver nitrate, expressed, bathed in the caustic soda solution, washed and dried; (6) gauze is treated as at (5) above, except that precipitation of silver precedes that of the gold. This subject-matter does not appear in the Specification as accepted.
GB12517/36A 1935-05-03 1936-05-02 Method of producing therapeutically and disinfectantly active substances Expired GB474614A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT474614X 1935-05-03

Publications (1)

Publication Number Publication Date
GB474614A true GB474614A (en) 1937-11-02

Family

ID=3674813

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12517/36A Expired GB474614A (en) 1935-05-03 1936-05-02 Method of producing therapeutically and disinfectantly active substances

Country Status (1)

Country Link
GB (1) GB474614A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134791A (en) * 1983-02-11 1984-08-22 Vernon Carus Ltd Antibacterial dressing
US9872501B2 (en) 2007-10-08 2018-01-23 Johnson & Johnson Vision Care, Inc. Methods for forming stabilized metal salt particles

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134791A (en) * 1983-02-11 1984-08-22 Vernon Carus Ltd Antibacterial dressing
US9872501B2 (en) 2007-10-08 2018-01-23 Johnson & Johnson Vision Care, Inc. Methods for forming stabilized metal salt particles

Similar Documents

Publication Publication Date Title
GB478134A (en) A process for removing salts from solutions
US2040806A (en) Substances containing silver and methods of producing the same
US2180637A (en) Amino acids product and method of manufacture
US4053568A (en) Process for the preparation of antacid aluminum hydroxycarbonate hydrate
ES460664A1 (en) Cerium sulfadiazine for treating burns
GB474614A (en) Method of producing therapeutically and disinfectantly active substances
GB476376A (en) Method of producing therapeutically and disinfectantly active substances
US2192285A (en) Substance containing gold and methods of producing the same
GB422948A (en) Method of producing therapeutically and disinfectantly active substances
NL70666C (en)
GB450575A (en) Improvements relating to the treatment of water and aqueous solutions
GB269909A (en) Improvements in or relating to treating residual liquors accruing from the treatment of cellulose material
SU364625A1 (en) METHOD OF OBTAINING COMPLEX COMPOUNDS
AT99936B (en) Process for the preparation of complex silver compounds of sulfur-containing carboxylic acids.
GB748283A (en) Improvements in or relating to organic metal compounds and processes for making such compounds
SU144988A1 (en) Method for extracting molybdenum from poor acid solutions by coprecipitation with ferrous hydroxide
GB169758A (en) Method of preparing colloidal metallic elements and compounds thereof
GB481164A (en) Process for the manufacture of therapeutically valuable gold compounds
GB1310788A (en) Process for the production of dopa
GB766992A (en) Improvements in or relating to the production of heparin
GB396456A (en) Improvements in or relating to the treatment of caustic soda solutions for the removal of sulphate therefrom
GB634566A (en) Preparation for treating the human body and process for the manufacture of such preparations
US1296344A (en) Method of producing zinc arsenite.
GB749512A (en) Improvements in or relating to the manufacture of pantetheine-4-phosphate and pantethine-4-phosphate
GB568182A (en) Improvements relating to the treatment of skin and leather materials