GB2134791A - Antibacterial dressing - Google Patents
Antibacterial dressing Download PDFInfo
- Publication number
- GB2134791A GB2134791A GB08403619A GB8403619A GB2134791A GB 2134791 A GB2134791 A GB 2134791A GB 08403619 A GB08403619 A GB 08403619A GB 8403619 A GB8403619 A GB 8403619A GB 2134791 A GB2134791 A GB 2134791A
- Authority
- GB
- United Kingdom
- Prior art keywords
- moss
- dressing
- sphagnum
- antibacterial
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A surgical dressing comprises Sphagnum moss treated with an effective quantity of an antibacterial agent comprising for example, one or more of metallic silver, gold, palladium, platinum and tin. A silver/carbon composite may also be used.
Description
SPECIFICATION
Antibacterial dressing
This invention relates to an antibacterial surgical dressing.
Sphagnum moss possesses a unique structure with leaves which contain wide, elongated cells having perforated walls. These cells provide a very high liquid absorptive capacity for the moss. A leaf may retain 20 to 25 times its own weight of water. The elongate cells are interconnected by short stalks, which facilitate ingress of liquid by capillary action. The cells are strengthened by spiral rings of resilient material which make the leaves elastic, this being a vital property for use in surgical dressings. Moss is also effective in wound healing since blood constituents are transmitted to adjacent leaf cells. In addition there is a concentration of leucocytes and the interface between the moss and the wound.
According to the present invention an antibacterial dressing comprises sphagnum moss treated with an effective quantity of an antibacterial agent.
In comparison to artificial fibres, moss has a vast inherent surface area. Very effective impregnation of moss with antibacterial agents may be achieved with thorough dissemination of the agent.
Particularly preferred antibacterial agents may comprise metallic silver, gold, palladium, platinum and tin or mixtures or composites containing these metals. Silver/carbon complexes may also be used. These may be applied by vacuum deposition or by sputtering onto dried specimens of the moss. Silver is especially preferred, this metal having been found to release silver ions at a sufficiently slow rate to be effective without risk of harming the patient. The slow release is believed to be facilitated by a galvanic interaction with the moss or with added metallic or non-metallic compounds.
The moss may comprise one or more species selected from: Sphagnum papillosum, Sphagnum palustre, Sphagnum magellanicum and
Sphagnum imbricatum although alternative mosses may be used.
The moss is preferably crimped to break any large stalks prior to treatment with the bactericide. The moss may be mixed with other natural or man-made fibres to produce a composite dressing.
A discontinuous coating of metal has been found to be advantageous in that wound-healing properties of the moss are not inhibited.
The dressing has been found to be effective against both gram positive and gram negative bacteria.
The dressing may incorporate a membrane which is permeable to air and vapours but is impermeable to liquids.
Such a membrane facilitates oxygen transfer but does allow penetration of bacteria to the wound.
Claims
1. An antibacterial surgical dressing comprising Sphagnum moss treated with an effective quantity of an antibacterial agent.
2. A dressing as claimed in claim 1, wherein the antibacterial agent is selected from: metallic silver, gold, palladium, platinum or tin or mixtures thereof.
3. A dressing as claimed in claim 1 or 2, comprising a silver/carbon composite material.
4. A dressing as claimed in claim 2, wherein the agent is applied to dried moss by vacuum disposition or by sputtering.
5. A dressing as claimed in any preceding claim, wherein the moss comprises one or more species selected from Sphagnum papillosum,
Sphagnum palustre, Sphagnum magellanicum and Sphagnum imbricatum.
6. A dressing as claimed in any preceding claim, wherein the moss is crimped prior to treatment with the antibacterial agent.
7. A dressing as claimed in any preceding claim, further comprising a man made or natural fibre.
8. A dressing as claimed in any preceding claim, comprising a membrane which is permeable to air but impermeable to liquids.
9. A dressing substantially as hereinbefore described.
**WARNING** end of DESC field may overlap start of CLMS **.
Claims (9)
1. An antibacterial surgical dressing comprising Sphagnum moss treated with an effective quantity of an antibacterial agent.
2. A dressing as claimed in claim 1, wherein the antibacterial agent is selected from: metallic silver, gold, palladium, platinum or tin or mixtures thereof.
3. A dressing as claimed in claim 1 or 2, comprising a silver/carbon composite material.
4. A dressing as claimed in claim 2, wherein the agent is applied to dried moss by vacuum disposition or by sputtering.
5. A dressing as claimed in any preceding claim, wherein the moss comprises one or more species selected from Sphagnum papillosum,
Sphagnum palustre, Sphagnum magellanicum and Sphagnum imbricatum.
6. A dressing as claimed in any preceding claim, wherein the moss is crimped prior to treatment with the antibacterial agent.
7. A dressing as claimed in any preceding claim, further comprising a man made or natural fibre.
8. A dressing as claimed in any preceding claim, comprising a membrane which is permeable to air but impermeable to liquids.
9. A dressing substantially as hereinbefore described.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08403619A GB2134791B (en) | 1983-02-11 | 1984-02-10 | Antibacterial dressing |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838303841A GB8303841D0 (en) | 1983-02-11 | 1983-02-11 | Antibacterial dressing |
GB08403619A GB2134791B (en) | 1983-02-11 | 1984-02-10 | Antibacterial dressing |
Publications (3)
Publication Number | Publication Date |
---|---|
GB8403619D0 GB8403619D0 (en) | 1984-03-14 |
GB2134791A true GB2134791A (en) | 1984-08-22 |
GB2134791B GB2134791B (en) | 1987-05-20 |
Family
ID=26285208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB08403619A Expired GB2134791B (en) | 1983-02-11 | 1984-02-10 | Antibacterial dressing |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB2134791B (en) |
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0255248A2 (en) * | 1986-07-24 | 1988-02-03 | Minnesota Mining And Manufacturing Company | Antimicrobial wound dressing |
DE4324994C1 (en) * | 1993-07-26 | 1995-02-23 | Demetron Gmbh | Equipment and sanitary articles for hospitals |
WO1995013704A1 (en) * | 1993-11-18 | 1995-05-26 | Westaim Technologies Inc. | Anti-microbial materials |
US5531726A (en) * | 1993-09-21 | 1996-07-02 | Johnson & Johnson, Inc. | Sphagnum moss composition for the production of sheeted absorbent and method for evaluating the potential of sphagnum moss material for absorbing liquid |
US5681575A (en) * | 1992-05-19 | 1997-10-28 | Westaim Technologies Inc. | Anti-microbial coating for medical devices |
US6017553A (en) * | 1992-05-19 | 2000-01-25 | Westaim Technologies, Inc. | Anti-microbial materials |
US6080490A (en) * | 1990-12-24 | 2000-06-27 | Westaim Technologies Inc. | Actively sterile surfaces |
US6365220B1 (en) | 1997-11-03 | 2002-04-02 | Nucryst Pharmaceuticals Corp. | Process for production of actively sterile surfaces |
US6897349B2 (en) | 1997-11-14 | 2005-05-24 | Acrymed | Silver-containing compositions, devices and methods for making |
WO2007077459A2 (en) * | 2006-01-05 | 2007-07-12 | Ntnu Technology Transfer As | Moss-derived antimicrobial composition |
EP1864634A3 (en) * | 1997-09-22 | 2009-09-30 | Argentum International, LLC | Multilayer conductive appliance having wound healing and analgesic properties |
US8192764B2 (en) | 2006-01-13 | 2012-06-05 | 3M Innovative Properties Company | Silver-containing antimicrobial articles and methods of manufacture |
US8227365B2 (en) | 2005-06-08 | 2012-07-24 | Ramachandran Nageswaran | Biocidal ceramic compositions, methods and articles of manufacture |
US8293965B2 (en) | 2006-04-28 | 2012-10-23 | Kimberly-Clark Worldwide, Inc. | Antimicrobial site dressings |
US8361553B2 (en) | 2004-07-30 | 2013-01-29 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for metal nanoparticle treated surfaces |
US8399027B2 (en) | 2005-04-14 | 2013-03-19 | 3M Innovative Properties Company | Silver coatings and methods of manufacture |
US8486426B2 (en) | 2002-07-29 | 2013-07-16 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for treatment of dermal conditions |
US8574610B2 (en) | 2006-09-07 | 2013-11-05 | Biolargo Life Technologies, Inc. | Material having antimicrobial activity when wet |
US8679523B2 (en) | 1999-12-30 | 2014-03-25 | Kimberly-Clark Worldwide, Inc. | Oxygen-delivery closed cell foam matrix for wound treatment |
US8900624B2 (en) | 2004-07-30 | 2014-12-02 | Kimberly-Clark Worldwide, Inc. | Antimicrobial silver compositions |
US9005449B2 (en) | 2011-09-07 | 2015-04-14 | Embro Corporation | Use of moss to reduce disinfection by-products in water treated with disinfectants |
US9289378B2 (en) | 2004-09-20 | 2016-03-22 | Avent, Inc. | Antimicrobial amorphous compositions |
US9795809B2 (en) | 2013-12-23 | 2017-10-24 | Embro Corporation | Use of moss to improve dental health |
US10251392B2 (en) | 2004-07-30 | 2019-04-09 | Avent, Inc. | Antimicrobial devices and compositions |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8801681B2 (en) | 1995-09-05 | 2014-08-12 | Argentum Medical, Llc | Medical device |
US8455710B2 (en) | 1997-09-22 | 2013-06-04 | Argentum Medical, Llc | Conductive wound dressings and methods of use |
US5814094A (en) | 1996-03-28 | 1998-09-29 | Becker; Robert O. | Iontopheretic system for stimulation of tissue healing and regeneration |
US6861570B1 (en) | 1997-09-22 | 2005-03-01 | A. Bart Flick | Multilayer conductive appliance having wound healing and analgesic properties |
US7214847B1 (en) | 1997-09-22 | 2007-05-08 | Argentum Medical, L.L.C. | Multilayer conductive appliance having wound healing and analgesic properties |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB422948A (en) * | 1933-05-15 | 1935-01-22 | Dozent Dr Fritz Feigl | Method of producing therapeutically and disinfectantly active substances |
GB474614A (en) * | 1935-05-03 | 1937-11-02 | Syngala Fabrik Fuer Chemisch S | Method of producing therapeutically and disinfectantly active substances |
GB863875A (en) * | 1957-05-11 | 1961-03-29 | Gustav Adolf Barth | Improved metallized wound dressing |
GB1270410A (en) * | 1969-09-25 | 1972-04-12 | Allor Corp | Colloidal composition and method of preparing the same |
-
1984
- 1984-02-10 GB GB08403619A patent/GB2134791B/en not_active Expired
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB422948A (en) * | 1933-05-15 | 1935-01-22 | Dozent Dr Fritz Feigl | Method of producing therapeutically and disinfectantly active substances |
GB474614A (en) * | 1935-05-03 | 1937-11-02 | Syngala Fabrik Fuer Chemisch S | Method of producing therapeutically and disinfectantly active substances |
GB863875A (en) * | 1957-05-11 | 1961-03-29 | Gustav Adolf Barth | Improved metallized wound dressing |
GB1270410A (en) * | 1969-09-25 | 1972-04-12 | Allor Corp | Colloidal composition and method of preparing the same |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4728323A (en) * | 1986-07-24 | 1988-03-01 | Minnesota Mining And Manufacturing Company | Antimicrobial wound dressings |
EP0255248A3 (en) * | 1986-07-24 | 1988-12-14 | Minnesota Mining And Manufacturing Company | Antimicrobial wound dressing |
EP0255248A2 (en) * | 1986-07-24 | 1988-02-03 | Minnesota Mining And Manufacturing Company | Antimicrobial wound dressing |
US6080490A (en) * | 1990-12-24 | 2000-06-27 | Westaim Technologies Inc. | Actively sterile surfaces |
US5681575A (en) * | 1992-05-19 | 1997-10-28 | Westaim Technologies Inc. | Anti-microbial coating for medical devices |
US5770255A (en) * | 1992-05-19 | 1998-06-23 | Westaim Technologies, Inc. | Anti-microbial coating for medical devices |
US6017553A (en) * | 1992-05-19 | 2000-01-25 | Westaim Technologies, Inc. | Anti-microbial materials |
DE4324994C1 (en) * | 1993-07-26 | 1995-02-23 | Demetron Gmbh | Equipment and sanitary articles for hospitals |
US5531726A (en) * | 1993-09-21 | 1996-07-02 | Johnson & Johnson, Inc. | Sphagnum moss composition for the production of sheeted absorbent and method for evaluating the potential of sphagnum moss material for absorbing liquid |
WO1995013704A1 (en) * | 1993-11-18 | 1995-05-26 | Westaim Technologies Inc. | Anti-microbial materials |
EP1864634A3 (en) * | 1997-09-22 | 2009-09-30 | Argentum International, LLC | Multilayer conductive appliance having wound healing and analgesic properties |
US6365220B1 (en) | 1997-11-03 | 2002-04-02 | Nucryst Pharmaceuticals Corp. | Process for production of actively sterile surfaces |
US6897349B2 (en) | 1997-11-14 | 2005-05-24 | Acrymed | Silver-containing compositions, devices and methods for making |
US8203029B2 (en) | 1997-11-14 | 2012-06-19 | Kimberly-Clark Worldwide, Inc. | Silver-containing compositions, devices and methods for making |
US7576255B2 (en) | 1997-11-14 | 2009-08-18 | Acrymed, Inc. | Silver-containing compositions, devices, and methods for making |
US8679523B2 (en) | 1999-12-30 | 2014-03-25 | Kimberly-Clark Worldwide, Inc. | Oxygen-delivery closed cell foam matrix for wound treatment |
US9687503B2 (en) | 1999-12-30 | 2017-06-27 | Avent, Inc. | Devices for delivering oxygen to the wounds |
US8486426B2 (en) | 2002-07-29 | 2013-07-16 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for treatment of dermal conditions |
US8361553B2 (en) | 2004-07-30 | 2013-01-29 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for metal nanoparticle treated surfaces |
US8900624B2 (en) | 2004-07-30 | 2014-12-02 | Kimberly-Clark Worldwide, Inc. | Antimicrobial silver compositions |
US10251392B2 (en) | 2004-07-30 | 2019-04-09 | Avent, Inc. | Antimicrobial devices and compositions |
US9888691B2 (en) | 2004-07-30 | 2018-02-13 | Avent, Inc. | Antimicrobial silver compositions |
US9289378B2 (en) | 2004-09-20 | 2016-03-22 | Avent, Inc. | Antimicrobial amorphous compositions |
US8399027B2 (en) | 2005-04-14 | 2013-03-19 | 3M Innovative Properties Company | Silver coatings and methods of manufacture |
US8227365B2 (en) | 2005-06-08 | 2012-07-24 | Ramachandran Nageswaran | Biocidal ceramic compositions, methods and articles of manufacture |
WO2007077459A2 (en) * | 2006-01-05 | 2007-07-12 | Ntnu Technology Transfer As | Moss-derived antimicrobial composition |
WO2007077459A3 (en) * | 2006-01-05 | 2007-11-29 | Ntnu Technology Transfer As | Moss-derived antimicrobial composition |
US8192764B2 (en) | 2006-01-13 | 2012-06-05 | 3M Innovative Properties Company | Silver-containing antimicrobial articles and methods of manufacture |
US8293965B2 (en) | 2006-04-28 | 2012-10-23 | Kimberly-Clark Worldwide, Inc. | Antimicrobial site dressings |
US8574610B2 (en) | 2006-09-07 | 2013-11-05 | Biolargo Life Technologies, Inc. | Material having antimicrobial activity when wet |
US9005449B2 (en) | 2011-09-07 | 2015-04-14 | Embro Corporation | Use of moss to reduce disinfection by-products in water treated with disinfectants |
US9795809B2 (en) | 2013-12-23 | 2017-10-24 | Embro Corporation | Use of moss to improve dental health |
Also Published As
Publication number | Publication date |
---|---|
GB8403619D0 (en) | 1984-03-14 |
GB2134791B (en) | 1987-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2134791A (en) | Antibacterial dressing | |
AU643058B2 (en) | Wound-covering materials | |
EP0068777B1 (en) | Composite wound dressing | |
EP2359784B1 (en) | Absorption body for attachment to human or animal skin surfaces | |
US4599226A (en) | Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation | |
EP0901382B1 (en) | Reinforced hydrogels | |
CA2490847C (en) | Antimicrobial, silver-containing wound dressing for continuous release | |
DE4026153C2 (en) | ||
US4446124A (en) | Wound dressing comprising silver sulfadiazine incorporated in animal tissue | |
JPH0824709B2 (en) | Sterilizing wound dressing | |
Smith Jr et al. | Microbiology and healing of the occluded skin-graft donor site | |
MX2008011571A (en) | Methods for producing silver-bonded antimicrobial moist wound dressings and moist wound dressings produced by the methods. | |
IE43853L (en) | Antiseptic compositions | |
Han | Interactive wound dressings | |
CN103074777A (en) | Silver-loaded alginate fiber and preparation method thereof | |
CN106344954A (en) | Bio-antimicrobial bacterial cellulose dressing and preparation method thereof | |
DE212010000186U1 (en) | Bactericidal sorbent material | |
NO162894C (en) | PROCEDURE FOR THE PREPARATION OF A COMPRESSION CONTAINING AIR CLEANING WOUND AND STIMULATING FOR HEALING. | |
DE3228851A1 (en) | Wound dressing | |
DE2635036A1 (en) | BIOLOGICAL DRESSING MATERIAL | |
CN116672488A (en) | Bismuth-containing burn dressing and preparation method thereof | |
RU2004122699A (en) | FIBER FIBER WITH HIGH ADSORPING ABILITY AND METHOD FOR PRODUCING IT | |
FR2392069A1 (en) | Highly absorbent cellulose fibres coated with water-insoluble polymer - swelling in water, e.g. CMC crosslinked with epihalohydrin (NL 28.11.78) | |
KR20140097728A (en) | Wound dressing foam containing cuttlefish bone powder and method for preparing the same | |
JPH1045608A (en) | Zeolite-containing therapeutic agent for wound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19940210 |