GB470925A - Improvements in or relating to the manufacture of pharmaceutical solutions - Google Patents

Improvements in or relating to the manufacture of pharmaceutical solutions

Info

Publication number
GB470925A
GB470925A GB552436A GB552436A GB470925A GB 470925 A GB470925 A GB 470925A GB 552436 A GB552436 A GB 552436A GB 552436 A GB552436 A GB 552436A GB 470925 A GB470925 A GB 470925A
Authority
GB
United Kingdom
Prior art keywords
quinine
fatty acids
added
morrhuate
oils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB552436A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB552436A priority Critical patent/GB470925A/en
Publication of GB470925A publication Critical patent/GB470925A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Quinine is added to heated cod-liver oil fatty acids (morrhuic acid) forming quinine morrhuate. Fatty acids of other animal or vegetable oils, e.g. olive, cottonseed or castor oil, or oleic acid may be used similarly.ALSO:A solution for injection in the treatment of varicose veins is prepared by making a solution of free quinine in an aqueous medium containing the sodium salt of a fatty acid obtainable from natural fats and oils. The quinine may be dissolved in hot benzyl alcohol and the solution mixed with hot aqueous sodium morrhuate, the product containing 5 or 10 per cent sodium morrhuate, and 2 per cent each of quinine and alcohol. Alternatively, the quinine is added to the free fatty acids of cod-liver oil and aqueous sodium hydroxide added to give a pH of 8-10. Benzyl alcohol may be added. Fatty acids of vegetable or animal oils, e.g. olive, cottonseed or castor oil, or oleic acid, or their sodium salts may be used similarly.
GB552436A 1936-02-24 1936-02-24 Improvements in or relating to the manufacture of pharmaceutical solutions Expired GB470925A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB552436A GB470925A (en) 1936-02-24 1936-02-24 Improvements in or relating to the manufacture of pharmaceutical solutions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB552436A GB470925A (en) 1936-02-24 1936-02-24 Improvements in or relating to the manufacture of pharmaceutical solutions

Publications (1)

Publication Number Publication Date
GB470925A true GB470925A (en) 1937-08-24

Family

ID=9797807

Family Applications (1)

Application Number Title Priority Date Filing Date
GB552436A Expired GB470925A (en) 1936-02-24 1936-02-24 Improvements in or relating to the manufacture of pharmaceutical solutions

Country Status (1)

Country Link
GB (1) GB470925A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009040381A1 (en) * 2009-09-07 2011-03-17 Kallimopoulos, Thomas, Dr. Process for the isolation of alkaloids from plants

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009040381A1 (en) * 2009-09-07 2011-03-17 Kallimopoulos, Thomas, Dr. Process for the isolation of alkaloids from plants
WO2011026637A3 (en) * 2009-09-07 2011-04-28 Thomas Kallimopoulos Methods for isolating alkaloids from plants

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