GB460249A - Manufacture of n-(aminoalkyl)-anthranilic acid alkyl esters - Google Patents

Manufacture of n-(aminoalkyl)-anthranilic acid alkyl esters

Info

Publication number
GB460249A
GB460249A GB21162/35A GB2116235A GB460249A GB 460249 A GB460249 A GB 460249A GB 21162/35 A GB21162/35 A GB 21162/35A GB 2116235 A GB2116235 A GB 2116235A GB 460249 A GB460249 A GB 460249A
Authority
GB
United Kingdom
Prior art keywords
anthranilic acid
ethyl ester
chloride
acid ethyl
aminoalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21162/35A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IG Farbenindustrie AG
Original Assignee
IG Farbenindustrie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IG Farbenindustrie AG filed Critical IG Farbenindustrie AG
Publication of GB460249A publication Critical patent/GB460249A/en
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B61RAILWAYS
    • B61FRAIL VEHICLE SUSPENSIONS, e.g. UNDERFRAMES, BOGIES OR ARRANGEMENTS OF WHEEL AXLES; RAIL VEHICLES FOR USE ON TRACKS OF DIFFERENT WIDTH; PREVENTING DERAILING OF RAIL VEHICLES; WHEEL GUARDS, OBSTRUCTION REMOVERS OR THE LIKE FOR RAIL VEHICLES
    • B61F17/00Lubrication specially adapted for axle-boxes of rail vehicles
    • B61F17/02Lubrication specially adapted for axle-boxes of rail vehicles with oil
    • B61F17/14Rotating lubricating devices
    • B61F17/20Rotating lubricating devices with scoops or the like attached to, or coupled with, the axle

Abstract

N-Aminoalkyl-anthranilic acid alkyl esters are prepared by treating an anthranilic acid alkyl ester with an aminoalkyl halide or by esterifying an N-aminoalkyl-anthranilic acid with an alcohol. The products possess therapeutic properties. Examples are given of the preparation of (1) N-b -diethylaminoethylanthranilic acid ethyl ester by heating anthranilic acid ethyl ester with b -diethylaminoethyl chloride in chloroform solution: (2) N-b -diethylaminoethyl - anthranilic acid butyl ester by esterifying N-b -diethylaminoethylanthranilic acid, obtained by reacting anthranilic acid with b -diethylaminoethyl chloride, with butyl alcohol either by heating the acid and excess of alcohol in the presence of hydrogen chloride or by interaction of the alcohol with the hydrochloride of the acid chloride, prepared by treating the acid with phosphorus pentachloride in benzene solution. The Specification as open to inspection under Sect. 91 describes also the preparation of (3) N-b -aminoethyl - anthranilic acid ethyl ester by heating anthranilic acid ethyl ester with the hydrochloride of b -aminoethyl chloride; (4) N-b -butylaminoethyl-anthranilic acid ethyl ester by using b -butylaminoethyl chloride, obtainable from b -butylaminoethanol and hydrochloric acid gas at 200 DEG C. with distillation of the water formed, in the process of (3); (5) N-b -piperidinoethyl - anthranilic acid ethyl ester from b -piperidinoethyl chloride and anthranilic acid ethyl ester. This subject-matter does not appear in the Specification as accepted. Reference has been directed by the Comptroller to French Patent of Addition Specification 22,632.
GB21162/35A 1934-07-26 1935-07-25 Manufacture of n-(aminoalkyl)-anthranilic acid alkyl esters Expired GB460249A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEI50255D DE631855C (en) 1934-07-26 1934-07-26 Process for the preparation of N- (aminoalkyl) -anthranilic acid alkyl esters

Publications (1)

Publication Number Publication Date
GB460249A true GB460249A (en) 1937-01-25

Family

ID=6539699

Family Applications (2)

Application Number Title Priority Date Filing Date
GB20223/28A Expired GB320399A (en) 1934-07-26 1928-07-11 Improvements in or relating to axle boxes
GB21162/35A Expired GB460249A (en) 1934-07-26 1935-07-25 Manufacture of n-(aminoalkyl)-anthranilic acid alkyl esters

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB20223/28A Expired GB320399A (en) 1934-07-26 1928-07-11 Improvements in or relating to axle boxes

Country Status (4)

Country Link
DE (1) DE631855C (en)
FR (1) FR657531A (en)
GB (2) GB320399A (en)
NL (1) NL21797C (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1153050B (en) * 1958-07-08 1963-08-22 Isothermos Sa Soc Gen Axle box, especially for dump trucks
US3870715A (en) * 1972-03-09 1975-03-11 Nikolaus R Hansl Substituted amino ethyl meta benzoic acid esters

Also Published As

Publication number Publication date
DE631855C (en) 1936-06-29
GB320399A (en) 1929-10-11
NL21797C (en)
FR657531A (en) 1929-06-04

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