GB432155A - The manufacture of primary phosphates of glycocol alkyl esters and n-alkyl derivatives thereof - Google Patents
The manufacture of primary phosphates of glycocol alkyl esters and n-alkyl derivatives thereofInfo
- Publication number
- GB432155A GB432155A GB2683234A GB2683234A GB432155A GB 432155 A GB432155 A GB 432155A GB 2683234 A GB2683234 A GB 2683234A GB 2683234 A GB2683234 A GB 2683234A GB 432155 A GB432155 A GB 432155A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- primary phosphates
- glycocol
- manufacture
- alkyl esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910019142 PO4 Inorganic materials 0.000 title abstract 3
- 235000021317 phosphate Nutrition 0.000 title abstract 3
- 150000003013 phosphoric acid derivatives Chemical class 0.000 title abstract 3
- 125000005907 alkyl ester group Chemical group 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- VXGABWCSZZWXPC-UHFFFAOYSA-N methyl 2-(methylamino)acetate Chemical compound CNCC(=O)OC VXGABWCSZZWXPC-UHFFFAOYSA-N 0.000 abstract 2
- 239000004471 Glycine Substances 0.000 abstract 1
- NTNZTEQNFHNYBC-UHFFFAOYSA-N ethyl 2-aminoacetate Chemical compound CCOC(=O)CN NTNZTEQNFHNYBC-UHFFFAOYSA-N 0.000 abstract 1
- 235000011007 phosphoric acid Nutrition 0.000 abstract 1
- 108700027361 sarcosine methyl ester Proteins 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
Abstract
Alkyl esters of glycine and of its N-alkyl derivatives are converted into their primary phosphates by reaction with substantially an equimolecular amount of orthophosphoric acid. The reaction is preferably effected at about 5 DEG C. in a solvent such as methanol, ethanol or ether. Examples are given of the preparation of the primary phosphates of glycine ethyl ester and sarcosine methyl ester. The products are of therapeutic value.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2683234A GB432155A (en) | 1934-09-18 | 1934-09-18 | The manufacture of primary phosphates of glycocol alkyl esters and n-alkyl derivatives thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2683234A GB432155A (en) | 1934-09-18 | 1934-09-18 | The manufacture of primary phosphates of glycocol alkyl esters and n-alkyl derivatives thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB432155A true GB432155A (en) | 1935-07-22 |
Family
ID=10249971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2683234A Expired GB432155A (en) | 1934-09-18 | 1934-09-18 | The manufacture of primary phosphates of glycocol alkyl esters and n-alkyl derivatives thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB432155A (en) |
-
1934
- 1934-09-18 GB GB2683234A patent/GB432155A/en not_active Expired
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