GB640477A - Production of hydroxy ketones from acetylenic alcohols - Google Patents
Production of hydroxy ketones from acetylenic alcoholsInfo
- Publication number
- GB640477A GB640477A GB33877/47A GB3387747A GB640477A GB 640477 A GB640477 A GB 640477A GB 33877/47 A GB33877/47 A GB 33877/47A GB 3387747 A GB3387747 A GB 3387747A GB 640477 A GB640477 A GB 640477A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alcohol
- group
- hydroxyketone
- hydration
- butanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/26—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydration of carbon-to-carbon triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/80—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Hydroxyketones are prepared by the hydration of the triple bond of an acetylenic alcohol of the general formula <FORM:0640477/IV (b)/1> wherein R1 and R2 represent alkyl radicals or may together form a hydroaromatic ring, by mixing together an aqueous solution of mercuric sulphate acidified with sulphuric acid with such an alcohol, the mixing being performed wholly at a temperature below 35 DEG C., and the amount of sulphuric acid including that which is in the form of mercuric sulphate being not over 64.4 grams per one gram molecular proportion of such alcohol, heating said mixture for about two hours to complete the said hydration, steam distilling the hydroxy ketone produced, and thereafter separating the hydroxyketone from the steam distillate. The group R1 may contain a plurality of carbon atoms, and the group R2 may represent the methyl group. The hydroxyketone may be isolated from the steam distillate by adsorbtion on active charcoal or silica gel, or by extraction with an ester which is insoluble in water, or by azeotropic dehydration with a solvent such as benzene or carbon tetrachloride. In the examples the following compounds are prepared: 3 : 3-dimethyl-3-hydroxy propanone-2, 1-acetyl-cyclohexanol, 3-isobutyl-3-butanol-2-one, and 3-ethyl-3-butanol-2-one. The last-named compound is obtained from 3-ethinyl-butinol-3 in admixture with methyl ethyl ketone and an unsaturated ketone of the formula <FORM:0640477/IV (b)/2>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US640477XA | 1946-12-23 | 1946-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB640477A true GB640477A (en) | 1950-07-19 |
Family
ID=22053226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB33877/47A Expired GB640477A (en) | 1946-12-23 | 1947-12-22 | Production of hydroxy ketones from acetylenic alcohols |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB640477A (en) |
-
1947
- 1947-12-22 GB GB33877/47A patent/GB640477A/en not_active Expired
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