GB300716A - Manufacture of arsenobenzenes - Google Patents
Manufacture of arsenobenzenesInfo
- Publication number
- GB300716A GB300716A GB22463/27A GB2246327A GB300716A GB 300716 A GB300716 A GB 300716A GB 22463/27 A GB22463/27 A GB 22463/27A GB 2246327 A GB2246327 A GB 2246327A GB 300716 A GB300716 A GB 300716A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- arsinic
- semicarbazone
- hydroxy
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000007659 semicarbazones Chemical class 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 4
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- -1 aromatic arsenic compound Chemical class 0.000 abstract 2
- 150000001495 arsenic compounds Chemical class 0.000 abstract 2
- ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical compound O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 abstract 1
- 229940093920 gynecological arsenic compound Drugs 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 229950008475 oxophenarsine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/74—Aromatic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
300,716. Albert, A. Aug. 26,1927. Arsenobenzenesare prepared by the reduction of an aromatic arsenic compound, or a mixture of two different aromatic arsenic compounds, in an acid medium using as reducing agent a mixture of hypophosphorous acid or a salt thereof with sulphurous acid or one of its salts. The proportions of hypophosphorous acid may be widely varied without affecting the nature of the product. but in the case of the sulphurous acid there should not be present more than one-third of a molecular proportion for each molecular proportion of the arsenic compound. If, however, one molecular proportion or more is used for each molecular proportion of the arsenic compound, arsenobenzenes are obtained which contain sulphur. Hydriodic acid or a salt thereof mav also be present. The products, which are crystalline, are useful therapeutically. Examples are given of the reduction of (1) the semicarbazone of 3 - aldehyde - 1 - phenoxyacetic acid-6-arsinic acid, (2) a mixture of the semicarhazones of 3-hydroxy-1-benzaldehyde-4-arsinic acid and of 3-aldehydo-1- phenoxyacetic acid-6- arsinic acid, (3) the semicarbazone of 1-benzaldehyde-3-hydroxy-4-arsinic acid, using various proportions of the reducing mixture, (4) the semicarbazone of 1-acetophenone-3-hydroxy-4-arsenoxide, (5) 3-aminobenzene-4-hydroxy-1-arsinic acid, using sufficient sulphurous acid to produce a sulphur-containing product. Specification 259,245 is referred to. The semicarbazone of 3-aldehydo-1-phenoxyacetic acid-6-arsinic acid is obtained by the action of chloracetic acid on the semicarbazone of 3- hydroxy-1-benzaldehyde-4-arsinic acid, whose preparation is described in Specification 259,245.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB22463/27A GB300716A (en) | 1927-08-26 | 1927-08-26 | Manufacture of arsenobenzenes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB22463/27A GB300716A (en) | 1927-08-26 | 1927-08-26 | Manufacture of arsenobenzenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB300716A true GB300716A (en) | 1928-11-22 |
Family
ID=10179764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22463/27A Expired GB300716A (en) | 1927-08-26 | 1927-08-26 | Manufacture of arsenobenzenes |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB300716A (en) |
-
1927
- 1927-08-26 GB GB22463/27A patent/GB300716A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB300716A (en) | Manufacture of arsenobenzenes | |
| US2164229A (en) | Symmetrical aromatic urea suitable for medicinal purposes | |
| GB444276A (en) | An improved process for the manufacture of medicinal preparations containing chlorophyll or chlorophylline | |
| US1298407A (en) | Salve. | |
| US1588252A (en) | Preparation of solutions of derivatives of dioxydiaminoarsenobenzene | |
| US1920311A (en) | Fungicibe | |
| GB348921A (en) | Manufacture of easily soluble salts of 3-acetylamino-4-hydroxy-benzene-arsonic acid | |
| US1424006A (en) | Manufacture of arsenical compounds | |
| US2262779A (en) | Quinic acid salts of aromatic sulphonamides | |
| GB292253A (en) | The manufacture of new phospho-tungsto-molybdenum compounds and the manufacture of lakes therefrom | |
| GB288370A (en) | The manufacture of new complex antimony compounds | |
| US1893226A (en) | Water soluble di-iodo-hydroxy-mercury fluorescein | |
| GB209768A (en) | ||
| US1581825A (en) | Germicidal composition | |
| GB398020A (en) | Process for the manufacture of complex double compounds of organic heavy metal mercapto compounds | |
| GB347101A (en) | Process for decreasing the inflammability of organic nitro compounds | |
| GB232284A (en) | Improvements in or relating to the manufacture of bread | |
| GB252099A (en) | Improvements in or relating to the preparation of soluble salts of substituted phenyl-arsinic acids | |
| GB468363A (en) | Manufacture of new organic arsenic compounds | |
| GB300538A (en) | Synthesis of aromatic arsenic compounds containing iodine | |
| GB292245A (en) | The manufacture of new complex bodies containing mercury | |
| GB327996A (en) | Process for the manufacture of organic stibinic acids and salts thereof | |
| GB321959A (en) | Process for the manufacture of compounds of diphenolisatins | |
| GB437798A (en) | Manufacture of condensation products of the naphthalene series | |
| GB249584A (en) | A process for the production of unsymmetrical arseno-benzene compounds |