GB2524831A - New pharmaceutical use - Google Patents

New pharmaceutical use Download PDF

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Publication number
GB2524831A
GB2524831A GB1406115.4A GB201406115A GB2524831A GB 2524831 A GB2524831 A GB 2524831A GB 201406115 A GB201406115 A GB 201406115A GB 2524831 A GB2524831 A GB 2524831A
Authority
GB
United Kingdom
Prior art keywords
patient
derivative
nbmi
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1406115.4A
Other languages
English (en)
Other versions
GB201406115D0 (en
Inventor
Boyd Eugene Haley
Ragnar Axel Theodor Klingberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EmeraMed Ltd
Original Assignee
Ermes Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50776843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2524831(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ermes Medical Co Ltd filed Critical Ermes Medical Co Ltd
Priority to GB1406115.4A priority Critical patent/GB2524831A/en
Publication of GB201406115D0 publication Critical patent/GB201406115D0/en
Priority to EP15723546.6A priority patent/EP3125876B8/en
Priority to NZ724678A priority patent/NZ724678A/en
Priority to RS20180210A priority patent/RS56905B1/sr
Priority to CN201580017210.4A priority patent/CN106132405B/zh
Priority to BR112016022880-4A priority patent/BR112016022880B1/pt
Priority to EA201692013A priority patent/EA032116B1/ru
Priority to PT157235466T priority patent/PT3125876T/pt
Priority to AU2015242374A priority patent/AU2015242374B2/en
Priority to SI201530158T priority patent/SI3125876T1/en
Priority to NO15723546A priority patent/NO3125876T3/no
Priority to PE2016001785A priority patent/PE20170586A1/es
Priority to US15/129,654 priority patent/US9782368B2/en
Priority to CA2944113A priority patent/CA2944113C/en
Priority to JP2016557313A priority patent/JP6474423B2/ja
Priority to DK15723546.6T priority patent/DK3125876T3/en
Priority to HRP20180325TT priority patent/HRP20180325T1/hr
Priority to SM20180116T priority patent/SMT201800116T1/it
Priority to PL15723546T priority patent/PL3125876T3/pl
Priority to PCT/GB2015/050999 priority patent/WO2015150793A1/en
Priority to MA39833A priority patent/MA39833B1/fr
Priority to KR1020167030801A priority patent/KR102482699B1/ko
Priority to HUE15723546A priority patent/HUE036206T2/hu
Priority to LTEP15723546.6T priority patent/LT3125876T/lt
Priority to MEP-2018-50A priority patent/ME03012B/me
Priority to MX2016012591A priority patent/MX2016012591A/es
Priority to UAA201611073A priority patent/UA119558C2/uk
Priority to ES15723546.6T priority patent/ES2659174T3/es
Priority to SG11201607478RA priority patent/SG11201607478RA/en
Publication of GB2524831A publication Critical patent/GB2524831A/en
Priority to ZA2016/06406A priority patent/ZA201606406B/en
Priority to IL248027A priority patent/IL248027B/en
Priority to CL2016002499A priority patent/CL2016002499A1/es
Priority to ECIEPI201678100A priority patent/ECSP16078100A/es
Priority to SA516371966A priority patent/SA516371966B1/ar
Priority to PH12016501975A priority patent/PH12016501975A1/en
Priority to CY20181100160T priority patent/CY1121235T1/el
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
GB1406115.4A 2014-04-04 2014-04-04 New pharmaceutical use Withdrawn GB2524831A (en)

Priority Applications (36)

Application Number Priority Date Filing Date Title
GB1406115.4A GB2524831A (en) 2014-04-04 2014-04-04 New pharmaceutical use
ES15723546.6T ES2659174T3 (es) 2014-04-04 2015-03-31 Nuevo uso de N,N-bis-2-mercaptoetil isoftalamida
SG11201607478RA SG11201607478RA (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide
SM20180116T SMT201800116T1 (it) 2014-04-04 2015-03-31 Nuovo uso di n,n-bis-2-mercaptoetil isoftalammide
PCT/GB2015/050999 WO2015150793A1 (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide
RS20180210A RS56905B1 (sr) 2014-04-04 2015-03-31 Nova upotreba n,n-bis-2-merkaptoetil izoftalamida
CN201580017210.4A CN106132405B (zh) 2014-04-04 2015-03-31 N,n-二-2-巯基乙基异邻苯二甲酰胺的用途
BR112016022880-4A BR112016022880B1 (pt) 2014-04-04 2015-03-31 Novo uso de n,n-bis-2-mercaptoetil isoftalamida
KR1020167030801A KR102482699B1 (ko) 2014-04-04 2015-03-31 N,n''-비스-2-머캅토에틸 이소프탈아미드의 용도
PT157235466T PT3125876T (pt) 2014-04-04 2015-03-31 Nova utilização de n, n-bis-2-mercaptoetil isoftalamida
AU2015242374A AU2015242374B2 (en) 2014-04-04 2015-03-31 New use of N,N-bis-2-mercaptoethyl isophthalamide
SI201530158T SI3125876T1 (en) 2014-04-04 2015-03-31 New use of N, N-bis-2-mercaptoethyl isophthalamide
NO15723546A NO3125876T3 (https=) 2014-04-04 2015-03-31
PE2016001785A PE20170586A1 (es) 2014-04-04 2015-03-31 Nuevo uso de n,n-bis-2-mercaptoetil isoftalamida
US15/129,654 US9782368B2 (en) 2014-04-04 2015-03-31 Use of N,N-bis-2-mercaptoethyl isophthalamide
CA2944113A CA2944113C (en) 2014-04-04 2015-03-31 Use of n,n-bis-2-mercaptoethyl isophthalamide in treating chronic obstructive pulmonary disease
JP2016557313A JP6474423B2 (ja) 2014-04-04 2015-03-31 Ｎ，ｎ−ビス−２−メルカプトエチルイソフタルアミドの新規な使用
DK15723546.6T DK3125876T3 (en) 2014-04-04 2015-03-31 NEW USE OF N, N-BIS-2-MERCAPTOETHYL-ISOPHTHALAMIDE
HRP20180325TT HRP20180325T1 (hr) 2014-04-04 2015-03-31 Nova uporaba n,n-bis-2-merkaptoetil izoftalamida
EP15723546.6A EP3125876B8 (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide
PL15723546T PL3125876T3 (pl) 2014-04-04 2015-03-31 Nowe zastosowanie n,n-bis-2-merkaptoetyloizoftalamidu
MA39833A MA39833B1 (fr) 2014-04-04 2015-03-31 Nouvelle utilisation du n,n-bis-2-mercaptoéthyl isophtalamide
NZ724678A NZ724678A (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide
EA201692013A EA032116B1 (ru) 2014-04-04 2015-03-31 Новое применение n,n-бис-2-меркаптоэтил-изофталамида
HUE15723546A HUE036206T2 (hu) 2014-04-04 2015-03-31 N,N-bisz-2-merkaptoetil-izoftálamid új alkalmazása
LTEP15723546.6T LT3125876T (lt) 2014-04-04 2015-03-31 N,n-bis-2-merkaptoetilizoftalamido naujas panaudojimas
MEP-2018-50A ME03012B (me) 2014-04-04 2015-03-31 Nova upotreba n,n-bis-2-merkaptoetil izoftalamida
MX2016012591A MX2016012591A (es) 2014-04-04 2015-03-31 Nuevo uso de n,n- bis-2-mercaptoetil isoftalamida.
UAA201611073A UA119558C2 (uk) 2014-04-04 2015-03-31 Застосування n,n-біс-2-меркаптоетилізофталаміду
ZA2016/06406A ZA201606406B (en) 2014-04-04 2016-09-16 New use of n,n-bis-2-mercaptoethyl isophthalamide
IL248027A IL248027B (en) 2014-04-04 2016-09-25 A new use of n,n-bis-2-mercaptoethyl isophthalamide
CL2016002499A CL2016002499A1 (es) 2014-04-04 2016-09-30 Nuevo uso de n,n - bis-2-mercaptoetil isoftalamida
ECIEPI201678100A ECSP16078100A (es) 2014-04-04 2016-09-30 Nuevo uso de n,n -2-bis- mercaptoetil isoftalamida
SA516371966A SA516371966B1 (ar) 2014-04-04 2016-10-01 استخدام جديد لـ n، n-بس-2- ميركابتو فينيل أيزوفثالاميد
PH12016501975A PH12016501975A1 (en) 2014-04-04 2016-10-04 New use of n,n-bis-2-mercaptoethyl isophthalamide
CY20181100160T CY1121235T1 (el) 2014-04-04 2018-02-09 Νεα χρηση toy ν,ν-δι-2-μερκαπτοαιθυλο ισοφθαλαμιδιου

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1406115.4A GB2524831A (en) 2014-04-04 2014-04-04 New pharmaceutical use

Publications (2)

Publication Number Publication Date
GB201406115D0 GB201406115D0 (en) 2014-05-21
GB2524831A true GB2524831A (en) 2015-10-07

Family

ID=50776843

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1406115.4A Withdrawn GB2524831A (en) 2014-04-04 2014-04-04 New pharmaceutical use

Country Status (36)

Country Link
US (1) US9782368B2 (https=)
EP (1) EP3125876B8 (https=)
JP (1) JP6474423B2 (https=)
KR (1) KR102482699B1 (https=)
CN (1) CN106132405B (https=)
AU (1) AU2015242374B2 (https=)
BR (1) BR112016022880B1 (https=)
CA (1) CA2944113C (https=)
CL (1) CL2016002499A1 (https=)
CY (1) CY1121235T1 (https=)
DK (1) DK3125876T3 (https=)
EA (1) EA032116B1 (https=)
EC (1) ECSP16078100A (https=)
ES (1) ES2659174T3 (https=)
GB (1) GB2524831A (https=)
HR (1) HRP20180325T1 (https=)
HU (1) HUE036206T2 (https=)
IL (1) IL248027B (https=)
LT (1) LT3125876T (https=)
MA (1) MA39833B1 (https=)
ME (1) ME03012B (https=)
MX (1) MX2016012591A (https=)
NO (1) NO3125876T3 (https=)
NZ (1) NZ724678A (https=)
PE (1) PE20170586A1 (https=)
PH (1) PH12016501975A1 (https=)
PL (1) PL3125876T3 (https=)
PT (1) PT3125876T (https=)
RS (1) RS56905B1 (https=)
SA (1) SA516371966B1 (https=)
SG (1) SG11201607478RA (https=)
SI (1) SI3125876T1 (https=)
SM (1) SMT201800116T1 (https=)
UA (1) UA119558C2 (https=)
WO (1) WO2015150793A1 (https=)
ZA (1) ZA201606406B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005057D0 (en) * 2020-04-06 2020-05-20 Emeramed Ltd New Use
CN114778234B (zh) * 2022-03-18 2025-08-15 武汉新烽光电股份有限公司 一种用于微流控总磷测试的抗坏血酸溶液的保存方法及保存结构
WO2026037909A1 (en) * 2024-08-16 2026-02-19 Emeramed Limited N,n-bis-2-mercaptoethyl isophthalamide for use in the treatment of pain

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227812A1 (en) * 2008-12-06 2010-09-09 Haley Boyd E Method of supplementing the diet and ameliorating oxidative stress

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586600B2 (en) * 2000-12-06 2003-07-01 University Of Kentucky Research Foundation Multidentate sulfur-containing ligands
JP2011026204A (ja) * 2007-11-26 2011-02-10 Rei Furukawa タバコの煙を吸入することにより引き起こされる疾患の予防及び／又は治療用組成物
JP2013505963A (ja) * 2009-09-28 2013-02-21 ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデイション 汚染された環境から元素を除去するチオール含有化合物およびその使用方法
US8575218B2 (en) * 2009-09-28 2013-11-05 The University Of Kentucky Research Foundation Thiol-containing compounds for the removal of elements from tissues and formulations therefor
US20110237776A1 (en) 2010-03-25 2011-09-29 Haley Boyd E Aromatic compounds with sulfur containing ligands
US8426368B2 (en) * 2010-03-25 2013-04-23 The University Of Kentucky Research Foundation Method of ameliorating oxidative stress and supplementing the diet

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227812A1 (en) * 2008-12-06 2010-09-09 Haley Boyd E Method of supplementing the diet and ameliorating oxidative stress

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Thiol-redox antioxidants protect against lung vascular endothelialcytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical and thiol-protectant, N-aetyl-1-cysteine, and novel thiol antioxidant, N,N'-bis-2-mercaptoethyl isophthalamide" *

Also Published As

Publication number Publication date
KR102482699B1 (ko) 2022-12-28
EP3125876B8 (en) 2018-01-24
PE20170586A1 (es) 2017-05-20
GB201406115D0 (en) 2014-05-21
ZA201606406B (en) 2018-04-25
US20170157072A1 (en) 2017-06-08
US9782368B2 (en) 2017-10-10
CY1121235T1 (el) 2020-05-29
DK3125876T3 (en) 2018-01-15
JP6474423B2 (ja) 2019-02-27
HRP20180325T1 (hr) 2018-04-06
MX2016012591A (es) 2017-04-06
PT3125876T (pt) 2018-02-22
RS56905B1 (sr) 2018-05-31
NZ724678A (en) 2022-12-23
AU2015242374A1 (en) 2016-10-13
SA516371966B1 (ar) 2019-04-14
ME03012B (me) 2018-10-20
CL2016002499A1 (es) 2017-01-27
PL3125876T3 (pl) 2018-05-30
EP3125876A1 (en) 2017-02-08
PH12016501975A1 (en) 2017-01-09
SG11201607478RA (en) 2016-10-28
EA201692013A1 (ru) 2017-03-31
UA119558C2 (uk) 2019-07-10
ES2659174T3 (es) 2018-03-14
LT3125876T (lt) 2018-02-12
KR20160140929A (ko) 2016-12-07
JP2017511307A (ja) 2017-04-20
CN106132405A (zh) 2016-11-16
EA032116B1 (ru) 2019-04-30
SMT201800116T1 (it) 2018-03-08
SI3125876T1 (en) 2018-04-30
NO3125876T3 (https=) 2018-04-28
BR112016022880A2 (https=) 2017-08-15
CN106132405B (zh) 2019-06-18
EP3125876B1 (en) 2017-11-29
AU2015242374B2 (en) 2019-10-10
MA39833B1 (fr) 2018-04-30
BR112016022880B1 (pt) 2022-09-13
ECSP16078100A (es) 2018-03-31
CA2944113A1 (en) 2015-10-08
WO2015150793A1 (en) 2015-10-08
CA2944113C (en) 2022-06-21
IL248027B (en) 2019-03-31
HUE036206T2 (hu) 2018-06-28
MA39833A (fr) 2017-02-08

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Legal Events

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COOA Change in applicant's name or ownership of the application

Owner name: ERMES MEDICAL COMPANY LIMITED

Free format text: FORMER OWNER: CTI SCIENCE LTD

WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)