BR112016022880B1 - Novo uso de n,n-bis-2-mercaptoetil isoftalamida - Google Patents

Novo uso de n,n-bis-2-mercaptoetil isoftalamida Download PDF

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Publication number
BR112016022880B1
BR112016022880B1 BR112016022880-4A BR112016022880A BR112016022880B1 BR 112016022880 B1 BR112016022880 B1 BR 112016022880B1 BR 112016022880 A BR112016022880 A BR 112016022880A BR 112016022880 B1 BR112016022880 B1 BR 112016022880B1
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BR
Brazil
Prior art keywords
nbmi
ascorbate
patient
copd
exposure
Prior art date
Application number
BR112016022880-4A
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English (en)
Portuguese (pt)
Other versions
BR112016022880A2 (https=
Inventor
Boyd Eugene Haley
Ragnar Axel Theodor Klingberg
Original Assignee
Emeramed Limited
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Application filed by Emeramed Limited filed Critical Emeramed Limited
Publication of BR112016022880A2 publication Critical patent/BR112016022880A2/pt
Publication of BR112016022880B1 publication Critical patent/BR112016022880B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112016022880-4A 2014-04-04 2015-03-31 Novo uso de n,n-bis-2-mercaptoetil isoftalamida BR112016022880B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1406115.4A GB2524831A (en) 2014-04-04 2014-04-04 New pharmaceutical use
GB1406115.4 2014-04-04
PCT/GB2015/050999 WO2015150793A1 (en) 2014-04-04 2015-03-31 New use of n,n-bis-2-mercaptoethyl isophthalamide

Publications (2)

Publication Number Publication Date
BR112016022880A2 BR112016022880A2 (https=) 2017-08-15
BR112016022880B1 true BR112016022880B1 (pt) 2022-09-13

Family

ID=50776843

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016022880-4A BR112016022880B1 (pt) 2014-04-04 2015-03-31 Novo uso de n,n-bis-2-mercaptoetil isoftalamida

Country Status (36)

Country Link
US (1) US9782368B2 (https=)
EP (1) EP3125876B8 (https=)
JP (1) JP6474423B2 (https=)
KR (1) KR102482699B1 (https=)
CN (1) CN106132405B (https=)
AU (1) AU2015242374B2 (https=)
BR (1) BR112016022880B1 (https=)
CA (1) CA2944113C (https=)
CL (1) CL2016002499A1 (https=)
CY (1) CY1121235T1 (https=)
DK (1) DK3125876T3 (https=)
EA (1) EA032116B1 (https=)
EC (1) ECSP16078100A (https=)
ES (1) ES2659174T3 (https=)
GB (1) GB2524831A (https=)
HR (1) HRP20180325T1 (https=)
HU (1) HUE036206T2 (https=)
IL (1) IL248027B (https=)
LT (1) LT3125876T (https=)
MA (1) MA39833B1 (https=)
ME (1) ME03012B (https=)
MX (1) MX2016012591A (https=)
NO (1) NO3125876T3 (https=)
NZ (1) NZ724678A (https=)
PE (1) PE20170586A1 (https=)
PH (1) PH12016501975A1 (https=)
PL (1) PL3125876T3 (https=)
PT (1) PT3125876T (https=)
RS (1) RS56905B1 (https=)
SA (1) SA516371966B1 (https=)
SG (1) SG11201607478RA (https=)
SI (1) SI3125876T1 (https=)
SM (1) SMT201800116T1 (https=)
UA (1) UA119558C2 (https=)
WO (1) WO2015150793A1 (https=)
ZA (1) ZA201606406B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202005057D0 (en) * 2020-04-06 2020-05-20 Emeramed Ltd New Use
CN114778234B (zh) * 2022-03-18 2025-08-15 武汉新烽光电股份有限公司 一种用于微流控总磷测试的抗坏血酸溶液的保存方法及保存结构
WO2026037909A1 (en) * 2024-08-16 2026-02-19 Emeramed Limited N,n-bis-2-mercaptoethyl isophthalamide for use in the treatment of pain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586600B2 (en) * 2000-12-06 2003-07-01 University Of Kentucky Research Foundation Multidentate sulfur-containing ligands
JP2011026204A (ja) * 2007-11-26 2011-02-10 Rei Furukawa タバコの煙を吸入することにより引き起こされる疾患の予防及び/又は治療用組成物
US8950583B2 (en) * 2008-12-06 2015-02-10 Ermes Medical Company Limited Method to remove heavy metals from a mammal
JP2013505963A (ja) * 2009-09-28 2013-02-21 ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデイション 汚染された環境から元素を除去するチオール含有化合物およびその使用方法
US8575218B2 (en) * 2009-09-28 2013-11-05 The University Of Kentucky Research Foundation Thiol-containing compounds for the removal of elements from tissues and formulations therefor
US20110237776A1 (en) 2010-03-25 2011-09-29 Haley Boyd E Aromatic compounds with sulfur containing ligands
US8426368B2 (en) * 2010-03-25 2013-04-23 The University Of Kentucky Research Foundation Method of ameliorating oxidative stress and supplementing the diet

Also Published As

Publication number Publication date
KR102482699B1 (ko) 2022-12-28
EP3125876B8 (en) 2018-01-24
PE20170586A1 (es) 2017-05-20
GB201406115D0 (en) 2014-05-21
ZA201606406B (en) 2018-04-25
US20170157072A1 (en) 2017-06-08
US9782368B2 (en) 2017-10-10
CY1121235T1 (el) 2020-05-29
DK3125876T3 (en) 2018-01-15
JP6474423B2 (ja) 2019-02-27
HRP20180325T1 (hr) 2018-04-06
MX2016012591A (es) 2017-04-06
PT3125876T (pt) 2018-02-22
RS56905B1 (sr) 2018-05-31
NZ724678A (en) 2022-12-23
AU2015242374A1 (en) 2016-10-13
SA516371966B1 (ar) 2019-04-14
ME03012B (me) 2018-10-20
CL2016002499A1 (es) 2017-01-27
PL3125876T3 (pl) 2018-05-30
EP3125876A1 (en) 2017-02-08
PH12016501975A1 (en) 2017-01-09
SG11201607478RA (en) 2016-10-28
EA201692013A1 (ru) 2017-03-31
UA119558C2 (uk) 2019-07-10
ES2659174T3 (es) 2018-03-14
LT3125876T (lt) 2018-02-12
KR20160140929A (ko) 2016-12-07
JP2017511307A (ja) 2017-04-20
CN106132405A (zh) 2016-11-16
GB2524831A (en) 2015-10-07
EA032116B1 (ru) 2019-04-30
SMT201800116T1 (it) 2018-03-08
SI3125876T1 (en) 2018-04-30
NO3125876T3 (https=) 2018-04-28
BR112016022880A2 (https=) 2017-08-15
CN106132405B (zh) 2019-06-18
EP3125876B1 (en) 2017-11-29
AU2015242374B2 (en) 2019-10-10
MA39833B1 (fr) 2018-04-30
ECSP16078100A (es) 2018-03-31
CA2944113A1 (en) 2015-10-08
WO2015150793A1 (en) 2015-10-08
CA2944113C (en) 2022-06-21
IL248027B (en) 2019-03-31
HUE036206T2 (hu) 2018-06-28
MA39833A (fr) 2017-02-08

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: EMERAMED LIMITED (IE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/03/2015, OBSERVADAS AS CONDICOES LEGAIS